Abnormal Expression of YAP Is Associated With Proliferation, Differentiation, Neutrophil Infiltration, and Adverse Outcome in Patients With Nasal Inverted Papilloma

by Tian Yuan, Tian Yuan, Rui Zheng, Xiang-min Zhou, Peng Jin, Zhi-qun Huang, Xiao-xue Zi, Qing-wu Wu, Wei-hao Wang, Hui-yi Deng, Wei-feng Kong, Hui-jun Qiu, Sui-zi Zhou, Qian-min Chen, Yan-yi Tu, Tao Li, Jing Liu, Jing Liu, Kai Sen Tan, Kai Sen Tan, Kai Sen Tan, Kai Sen Tan, Hsiao Hui Ong, Hsiao Hui Ong, Li Shi, Zhuang-gui Chen, Xue-kun Huang, Qin-tai Yang, De-yun Wang, De-yun Wang
Published 2021-04-01

Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics

by Joe Wee Jian Ong, Kai Sen Tan, Siok Ghee Ler, Jayantha Gunaratne, Hyungwon Choi, Ju Ee Seet, Vincent Tak-Kwong Chow
Published 2019-08-01

FGF2, an Immunomodulatory Factor in Asthma and Chronic Obstructive Pulmonary Disease (COPD)

by Yuanyang Tan, Yongkang Qiao, Zhuanggui Chen, Jing Liu, Yanrong Guo, Thai Tran, Kai Sen Tan, De-Yun Wang, Yan Yan, Yan Yan
Published 2020-04-01

Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps

by Haiyu Hong, Dan Wang, Kai Sen Tan, Rui Zheng, Fenghong Chen, Wenxiang Gao, Haixin He, Jianbo Shi, Yunping Fan, Qintai Yang, Yueqi Sun
Published 2018-07-01

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status

by Yan-Rong Guo, Qing-Dong Cao, Zhong-Si Hong, Yuan-Yang Tan, Shou-Deng Chen, Hong-Jun Jin, Kai-Sen Tan, De-Yun Wang, Yan Yan
Published 2020-03-01

Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures

by Kai Sen Tan, Yan Yan, Yan Yan, Wai Ling Hiromi Koh, Liang Li, Hyungwon Choi, Hyungwon Choi, Thai Tran, Richard Sugrue, De Yun Wang, Vincent T. Chow
Published 2018-11-01

p63+Krt5+ basal cells are increased in the squamous metaplastic epithelium of patients with radiation-induced chronic Rhinosinusitis

by Hongming Huang, Kai Sen Tan, Suizi Zhou, Tian Yuan, Jing Liu, Hsiao Hui Ong, Qianmin Chen, Junxiao Gao, Minghong Xu, Zhenchao Zhu, Qianhui Qiu, De Yun Wang
Published 2020-09-01

Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection

by Zhuang Gui Chen, Zhao Ni Wang, Yan Yan, Jing Liu, Ting Ting He, Kim Thye Thong, Yew Kwang Ong, Vincent T. K. Chow, Kai Sen Tan, De Yun Wang
Published 2019-07-01

Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium

by Kai Sen Tan, Rachel Liyu Lim, Jing Liu, Hsiao Hui Ong, Vivian Jiayi Tan, Hui Fang Lim, Hui Fang Lim, Kian Fan Chung, Ian M. Adcock, Vincent T. Chow, De Yun Wang
Published 2020-02-01

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles.

by Akshamal M Gamage, Kai Sen Tan, Wharton O Y Chan, Jing Liu, Chee Wah Tan, Yew Kwang Ong, Mark Thong, Anand K Andiappan, Danielle E Anderson, De Yun Wang, Lin-Fa Wang
Published 2020-12-01

Host Antiviral Response Suppresses Ciliogenesis and Motile Ciliary Functions in the Nasal Epithelium

by Qianmin Chen, Qianmin Chen, Kai Sen Tan, Jing Liu, Hsiao Hui Ong, Suizi Zhou, Suizi Zhou, Hongming Huang, Hongming Huang, Hailing Chen, Yew Kwang Ong, Mark Thong, Vincent T. Chow, Qianhui Qiu, De-Yun Wang
Published 2020-12-01

Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps

by Yang Peng, Wei-jie Guan, Kai Sen Tan, Zhenchao Zhu, Zhuo Chen, Haiyu Hong, Zhaoni Wang, Tengfei Tian, Xiaoxue Zi, Yew Kwang Ong, Mark Thong, Li Shi, Qintai Yang, Qianhui Qiu, De-Yun Wang
Published 2018-11-01

An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps

by Xiao-xue Zi, Xiao-xue Zi, Wei-jie Guan, Wei-jie Guan, Yang Peng, Yang Peng, Kai Sen Tan, Jing Liu, Ting-ting He, Yew-kwang Ong, Mark Thong, Li Shi, De-yun Wang
Published 2019-11-01

A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

by Annika Luukkainen, Annika Luukkainen, Kia Joo Puan, Nurhashikin Yusof, Bernett Lee, Kai Sen Tan, Jing Liu, Yan Yan, Sanna Toppila-Salmi, Sanna Toppila-Salmi, Risto Renkonen, Risto Renkonen, Vincent T. Chow, Olaf Rotzschke, De Yun Wang
Published 2018-11-01

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications

by Kai Sen Tan, Anand Kumar Andiappan, Bernett Lee, Yan Yan, Jing Liu, See Aik Tang, Josephine Lum, Ting Ting He, Yew Kwang Ong, Mark Thong, Hui Fang Lim, Hyung Won Choi, Olaf Rotzschke, Vincent T Chow, De Yun Wang
Published 2019-08-01

Interleukin-13 Alters Tight Junction Proteins Expression Thereby Compromising Barrier Function and Dampens Rhinovirus Induced Immune Responses in Nasal Epithelium

by Zhi-Qun Huang, Zhi-Qun Huang, Zhi-Qun Huang, Jing Liu, Hsiao Hui Ong, Tian Yuan, Tian Yuan, Xiang-Min Zhou, Xiang-Min Zhou, Jun Wang, Kai Sen Tan, Vincent T. Chow, Qin-Tai Yang, Li Shi, Jing Ye, De-Yun Wang
Published 2020-09-01