Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

by Marie P Fogarty, Maren E Cannon, Swarooparani Vadlamudi, Kyle J Gaulton, Karen L Mohlke
Published 2014-09-01

Association studies with imputed variants using expectation-maximization likelihood-ratio tests.

by Kuan-Chieh Huang, Wei Sun, Ying Wu, Mengjie Chen, Karen L Mohlke, Leslie A Lange, Yun Li
Published 2014-01-01

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

by Markku Laakso, Johanna Kuusisto, Alena Stančáková, Teemu Kuulasmaa, Päivi Pajukanta, Aldons J. Lusis, Francis S. Collins, Karen L. Mohlke, Michael Boehnke
Published 2017-03-01

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

by Yan Liu, Hanna K Sanoff, Hyunsoon Cho, Christin E Burd, Chad Torrice, Karen L Mohlke, Joseph G Ibrahim, Nancy E Thomas, Norman E Sharpless
Published 2009-01-01

Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels[S]

by Ying Wu, Amanda F. Marvelle, Jin Li, Damien C. Croteau-Chonka, Alan B. Feranil, Christopher W. Kuzawa, Yun Li, Linda S. Adair, Karen L. Mohlke
Published 2013-11-01

Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs

by Wujuan Zhong, Li Dong, Taylor B. Poston, Toni Darville, Cassandra N. Spracklen, Di Wu, Di Wu, Karen L. Mohlke, Yun Li, Yun Li, Quefeng Li, Xiaojing Zheng, Xiaojing Zheng
Published 2020-02-01

Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

by Maren E. Cannon, Kevin W. Currin, Kristin L. Young, Hannah J. Perrin, Swarooparani Vadlamudi, Alexias Safi, Lingyun Song, Ying Wu, Martin Wabitsch, Markku Laakso, Gregory E. Crawford, Karen L. Mohlke
Published 2019-08-01

The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance.

by Zong Miao, Marcus Alvarez, Arthur Ko, Yash Bhagat, Elior Rahmani, Brandon Jew, Sini Heinonen, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Carlos Aguilar-Salinas, Teresa Tusie-Luna, Karen L Mohlke, Markku Laakso, Kirsi H Pietiläinen, Eran Halperin, Päivi Pajukanta
Published 2020-09-01

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

by Maren E. Cannon, Qing Duan, Ying Wu, Monica Zeynalzadeh, Zheng Xu, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, Mete Civelek, Aldons J. Lusis, Johanna Kuusisto, Francis S. Collins, Michael Boehnke, Hua Tang, Markku Laakso, Yun Li, Karen L. Mohlke
Published 2017-09-01

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published 2018-08-01

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published 2018-04-01

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

by James P Davis, Jeroen R Huyghe, Adam E Locke, Anne U Jackson, Xueling Sim, Heather M Stringham, Tanya M Teslovich, Ryan P Welch, Christian Fuchsberger, Narisu Narisu, Peter S Chines, Antti J Kangas, Pasi Soininen, Mika Ala-Korpela, Johanna Kuusisto, Francis S Collins, Markku Laakso, Michael Boehnke, Karen L Mohlke
Published 2017-10-01

Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.

by Cassandra N Spracklen, Jinxiu Shi, Swarooparani Vadlamudi, Ying Wu, Meng Zou, Chelsea K Raulerson, James P Davis, Monica Zeynalzadeh, Kayla Jackson, Wentao Yuan, Haifeng Wang, Weihua Shou, Ying Wang, Jingchun Luo, Leslie A Lange, Ethan M Lange, Barry M Popkin, Penny Gordon-Larsen, Shufa Du, Wei Huang, Karen L Mohlke
Published 2018-04-01

Identification of Novel Candidate Genes and Variants for Hearing Loss and Temporal Bone Anomalies

by Regie Lyn P. Santos-Cortez, Talitha Karisse L. Yarza, Tori C. Bootpetch, Ma. Leah C. Tantoco, Karen L. Mohlke, Teresa Luisa G. Cruz, Mary Ellen Chiong Perez, Abner L. Chan, Nanette R. Lee, Celina Ann M. Tobias-Grasso, Maria Rina T. Reyes-Quintos, Eva Maria Cutiongco-de la Paz, Charlotte M. Chiong
Published 2021-04-01

Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

by David Z. Pan, Zong Miao, Caroline Comenho, Sandhya Rajkumar, Amogha Koka, Seung Hyuk T. Lee, Marcus Alvarez, Dorota Kaminska, Arthur Ko, Janet S. Sinsheimer, Karen L. Mohlke, Nicholas Mancuso, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Maria Teresa Tusié-Luna, Carlos Aguilar-Salinas, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Markku Laakso, Kristina M. Garske, Päivi Pajukanta
Published 2021-08-01

Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

by David Z. Pan, Zong Miao, Caroline Comenho, Sandhya Rajkumar, Amogha Koka, Seung Hyuk T. Lee, Marcus Alvarez, Dorota Kaminska, Arthur Ko, Janet S. Sinsheimer, Karen L. Mohlke, Nicholas Mancuso, Linda Liliana Muñoz-Hernandez, Miguel Herrera-Hernandez, Maria Teresa Tusié-Luna, Carlos Aguilar-Salinas, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Markku Laakso, Kristina M. Garske, Päivi Pajukanta
Published 2021-08-01

Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

by Amy R. Johnson, Yuanyuan Qin, Alyssa J. Cozzo, Alex J. Freemerman, Megan J. Huang, Liyang Zhao, Brante P. Sampey, J. Justin Milner, Melinda A. Beck, Blossom Damania, Naim Rashid, Joseph A. Galanko, Douglas P. Lee, Matthew L. Edin, Darryl C. Zeldin, Patrick T. Fueger, Brittney Dietz, Andreas Stahl, Ying Wu, Karen L. Mohlke, Liza Makowski
Published 2016-07-01

Fine-mapping and initial characterization of QT interval loci in African Americans.

by Christy L Avery, Praveen Sethupathy, Steven Buyske, Qianchuan He, Dan-Yu Lin, Dan E Arking, Cara L Carty, David Duggan, Megan D Fesinmeyer, Lucia A Hindorff, Janina M Jeff, Liviu Klein, Kristen K Patton, Ulrike Peters, Ralph V Shohet, Nona Sotoodehnia, Alicia M Young, Charles Kooperberg, Christopher A Haiman, Karen L Mohlke, Eric A Whitsel, Kari E North
Published 2012-01-01

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.

by Cassandra N Spracklen, Apoorva K Iyengar, Swarooparani Vadlamudi, Chelsea K Raulerson, Anne U Jackson, Sarah M Brotman, Ying Wu, Maren E Cannon, James P Davis, Aaron T Crain, Kevin W Currin, Hannah J Perrin, Narisu Narisu, Heather M Stringham, Christian Fuchsberger, Adam E Locke, Ryan P Welch, Johanna K Kuusisto, Päivi Pajukanta, Laura J Scott, Yun Li, Francis S Collins, Michael Boehnke, Markku Laakso, Karen L Mohlke
Published 2020-09-01

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

by Laura J. Scott, Michael R. Erdos, Jeroen R. Huyghe, Ryan P. Welch, Andrew T. Beck, Brooke N. Wolford, Peter S. Chines, John P. Didion, Narisu Narisu, Heather M. Stringham, D. Leland Taylor, Anne U. Jackson, Swarooparani Vadlamudi, Lori L. Bonnycastle, Leena Kinnunen, Jouko Saramies, Jouko Sundvall, Ricardo D'Oliveira Albanus, Anna Kiseleva, John Hensley, Gregory E. Crawford, Hui Jiang, Xiaoquan Wen, Richard M. Watanabe, Timo A. Lakka, Karen L. Mohlke, Markku Laakso, Jaakko Tuomilehto, Heikki A. Koistinen, Michael Boehnke, Francis S. Collins, Stephen C. J. Parker
Published 2016-06-01