A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum

by Karen V. Lithgow, Rebecca Hof, Charmaine Wetherell, Drew Phillips, Simon Houston, Caroline E. Cameron
Published 2017-02-01

Identification of the Neuroinvasive Pathogen Host Target, LamR, as an Endothelial Receptor for the Treponema pallidum Adhesin Tp0751

by Karen V. Lithgow, Brigette Church, Alloysius Gomez, Emily Tsao, Simon Houston, Leigh Anne Swayne, Caroline E. Cameron
Published 2020-04-01

Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism

by Karen V. Lithgow, Emily Tsao, Ethan Schovanek, Alloysius Gomez, Leigh Anne Swayne, Caroline E. Cameron, Caroline E. Cameron
Published 2021-07-01

Characterizing the Syphilis-Causing Treponema pallidum ssp. pallidum Proteome Using Complementary Mass Spectrometry.

by Kara K Osbak, Simon Houston, Karen V Lithgow, Conor J Meehan, Michal Strouhal, David Šmajs, Caroline E Cameron, Xaveer Van Ostade, Chris R Kenyon, Geert A Van Raemdonck
Published 2016-09-01

The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host...

by Michelle L Parker, Simon Houston, Helena Pětrošová, Karen V Lithgow, Rebecca Hof, Charmaine Wetherell, Wei-Chien Kao, Yi-Pin Lin, Tara J Moriarty, Rhodaba Ebady, Caroline E Cameron, Martin J Boulanger
Published 2016-09-01

Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

by Wei-Chien Andrew Kao, Helena Pětrošová, Rhodaba Ebady, Karen V. Lithgow, Pablo Rojas, Yang Zhang, Yae-Eun Kim, Yae-Ram Kim, Tanya Odisho, Nupur Gupta, Annette Moter, Caroline E. Cameron, Tara J. Moriarty
Published 2017-05-01