Innate immune sensing of DNA.

by Shruti Sharma, Katherine A Fitzgerald
Published 2011-04-01

Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection

by Federica Agliano, Katherine A. Fitzgerald, Anthony T. Vella, Vijay A. Rathinam, Andrei E. Medvedev
Published 2020-01-01

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

by Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, John J. Kaminski, Mikayla R. Thompson
Published 2011-06-01

The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans

by Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard K. Kandasamy, Emiliano Ricci, Katherine A. Fitzgerald
Published 2020-12-01

A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.

by Jeffrey Tomalka, Sandhya Ganesan, Elaheh Azodi, Krupen Patel, Parth Majmudar, Brian A Hall, Katherine A Fitzgerald, Amy G Hise
Published 2011-12-01

Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling.

by Felix Geeraedts, Nadege Goutagny, Veit Hornung, Martina Severa, Aalzen de Haan, Judith Pool, Jan Wilschut, Katherine A Fitzgerald, Anke Huckriede
Published 2008-08-01

Dual Engagement of the NLRP3 and AIM2 Inflammasomes by Plasmodium-Derived Hemozoin and DNA during Malaria

by Parisa Kalantari, Rosane B. DeOliveira, Jennie Chan, Yolanda Corbett, Vijay Rathinam, Andrea Stutz, Eicke Latz, Ricardo T. Gazzinelli, Douglas T. Golenbock, Katherine A. Fitzgerald
Published 2014-01-01

NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.

by Amit K Pandey, Yibin Yang, Zhaozhao Jiang, Sarah M Fortune, Francois Coulombe, Marcel A Behr, Katherine A Fitzgerald, Christopher M Sassetti, Michelle A Kelliher
Published 2009-07-01

Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4

by Warrison A. Andrade, Sarika Agarwal, Shunyan Mo, Scott A. Shaffer, Joseph P. Dillard, Tobias Schmidt, Veit Hornung, Katherine A. Fitzgerald, Evelyn A. Kurt-Jones, Douglas T. Golenbock
Published 2016-06-01

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE

by Mona Motwani, Jason McGowan, Jennifer Antonovitch, Kevin MingJie Gao, Zhaozhao Jiang, Shruti Sharma, Gretchen A. Baltus, Kevin M. Nickerson, Ann Marshak-Rothstein, Katherine A. Fitzgerald
Published 2021-03-01

Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

by Line S. Reinert, Katarína Lopušná, Henriette Winther, Chenglong Sun, Martin K. Thomsen, Ramya Nandakumar, Trine H. Mogensen, Morten Meyer, Christian Vægter, Jens R. Nyengaard, Katherine A. Fitzgerald, Søren R. Paludan
Published 2016-11-01

Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.

by Marco A Ataide, Warrison A Andrade, Dario S Zamboni, Donghai Wang, Maria do Carmo Souza, Bernardo S Franklin, Samir Elian, Flaviano S Martins, Dhelio Pereira, George Reed, Katherine A Fitzgerald, Douglas T Golenbock, Ricardo T Gazzinelli
Published 2014-01-01

Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria

by Larissa M. N. Pereira, Patrícia A. Assis, Natalia M. de Araújo, Danielle F. Durso, Caroline Junqueira, Marco Antônio Ataíde, Dhelio B. Pereira, Egil Lien, Katherine A. Fitzgerald, Dario S. Zamboni, Douglas T. Golenbock, Ricardo T. Gazzinelli
Published 2020-11-01

Caspase-8 mediates inflammation and disease in rodent malaria

by Larissa M. N. Pereira, Patrícia A. Assis, Natalia M. de Araújo, Danielle F. Durso, Caroline Junqueira, Marco Antônio Ataíde, Dhelio B. Pereira, Egil Lien, Katherine A. Fitzgerald, Dario S. Zamboni, Douglas T. Golenbock, Ricardo T. Gazzinelli
Published 2020-09-01

Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

by Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle
Published 2010-11-01

Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2

by Roland Elling, Elektra K. Robinson, Barbara Shapleigh, Stephen C. Liapis, Sergio Covarrubias, Sol Katzman, Abigail F. Groff, Zhaozhao Jiang, Shiuli Agarwal, Mona Motwani, Jennie Chan, Shruti Sharma, Elizabeth J. Hennessy, Garret A. FitzGerald, Michael T. McManus, John L. Rinn, Katherine A. Fitzgerald, Susan Carpenter
Published 2018-11-01

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

by Christian K. Holm, Stine H. Rahbek, Hans Henrik Gad, Rasmus O. Bak, Martin R. Jakobsen, Zhaozaho Jiang, Anne Louise Hansen, Simon K. Jensen, Chenglong Sun, Martin K. Thomsen, Anders Laustsen, Camilla G. Nielsen, Kasper Severinsen, Yingluo Xiong, Dara L. Burdette, Veit Hornung, Robert Jan Lebbink, Mogens Duch, Katherine A. Fitzgerald, Shervin Bahrami, Jakob Giehm Mikkelsen, Rune Hartmann, Søren R. Paludan
Published 2016-02-01

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

by David Olagnier, Aske M. Brandtoft, Camilla Gunderstofte, Nikolaj L. Villadsen, Christian Krapp, Anne L. Thielke, Anders Laustsen, Suraj Peri, Anne Louise Hansen, Lene Bonefeld, Jacob Thyrsted, Victor Bruun, Marie B. Iversen, Lin Lin, Virginia M. Artegoitia, Chenhe Su, Long Yang, Rongtuan Lin, Siddharth Balachandran, Yonglun Luo, Mette Nyegaard, Bernadette Marrero, Raphaela Goldbach-Mansky, Mona Motwani, Dylan G. Ryan, Katherine A. Fitzgerald, Luke A. O’Neill, Anne K. Hollensen, Christian K. Damgaard, Frank v. de Paoli, Hanne C. Bertram, Martin R. Jakobsen, Thomas B. Poulsen, Christian K. Holm
Published 2018-08-01