NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment

by Lei Yin, Fangping Bao, Jing Wu, Kuanyu Li
Published 2018-09-01

Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage

by Shuangying Hao, Chuanhui Song, Longcheng Shang, Jiang Yu, Tong Qiao, Kuanyu Li
Published 2016-03-01

Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet.

by Meng Zhang, Hongting Zhao, Jing Cai, Huihui Li, Qi Wu, Tong Qiao, Kuanyu Li
Published 2017-01-01

Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits

by Jing Wu, Jian-Jun Yang, Yan Cao, Huihui Li, Hongting Zhao, Shuofei Yang, Kuanyu Li
Published 2020-04-01

Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW...

by Shuangying Hao, Jiajie Ji, Hongting Zhao, Longcheng Shang, Jing Wu, Huihui Li, Tong Qiao, Kuanyu Li
Published 2015-12-01

A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.

by Jing Wu, Huihui Li, Xiaoru Sun, Hui Zhang, Shuangying Hao, Muhuo Ji, Jianjun Yang, Kuanyu Li
Published 2015-01-01

Expression of human frataxin is regulated by transcription factors SRF and TFAP2.

by Kuanyu Li, Anamika Singh, Daniel R Crooks, Xiaoman Dai, Zhuangzhuang Cong, Liang Pan, Dung Ha, Tracey A Rouault
Published 2010-08-01

Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis

by Jing Cai, Meng Zhang, Yutong Liu, Huihui Li, Longcheng Shang, Tianze Xu, Zhipeng Chen, Fudi Wang, Tong Qiao, Kuanyu Li
Published 2020-11-01

GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a

by Yuchen Pan, Jiali Wang, Yaxian Xue, Jiaojiao Zhao, Dan Li, Shaolong Zhang, Kuanyu Li, Yayi Hou, Yayi Hou, Hongye Fan
Published 2018-10-01

Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats

by Jian-Jun Yang, Kuanyu Li, Jing Wu, Shuangying Hao, Xiao-Ru Sun, Hui Zhang, Huihui Li, Hongting Zhao, Mu-Huo Ji
Published 2017-04-01

Neuroprotective Effect of Oridonin on Traumatic Brain Injury via Inhibiting NLRP3 Inflammasome in Experimental Mice

by Chaolong Yan, Huiying Yan, Jiannan Mao, Yutong Liu, Li Xu, Hongting Zhao, Jiaqi Shen, Yan Cao, Yongyue Gao, Kuanyu Li, Wei Jin, Wei Jin
Published 2020-11-01

Novel frataxin isoforms may contribute to the pathological mechanism of Friedreich ataxia.

by Haiyan Xia, Yun Cao, Xiaoman Dai, Zvonimir Marelja, Di Zhou, Ran Mo, Sahar Al-Mahdawi, Mark A Pook, Silke Leimkühler, Tracey A Rouault, Kuanyu Li
Published 2012-01-01

Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological Disorder Induced by Deficiency of Irp2

by Jiaqi Shen, Li Xu, Yuxuan Li, Weichen Dong, Jing Cai, Yutong Liu, Hongting Zhao, Tianze Xu, Esther Meyron Holtz, Yanzhong Chang, Tong Qiao, Kuanyu Li
Published 2021-10-01