Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?

by David A. Jans, Kylie M. Wagstaff
Published 2020-09-01

Internalized Functional DNA Aptamers as Alternative Cancer Therapies

by Morgan L. Marshall, Kylie M. Wagstaff
Published 2020-07-01

Nuclear import of β-dystroglycan is facilitated by ezrin-mediated cytoskeleton reorganization.

by Alejandra Vásquez-Limeta, Kylie M Wagstaff, Arturo Ortega, Dorothy H Crouch, David A Jans, Bulmaro Cisneros
Published 2014-01-01

Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.

by Caitlin L Rowe, Kylie M Wagstaff, Sibil Oksayan, Dominic J Glover, David A Jans, Gregory W Moseley
Published 2016-01-01

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus

by Hareth A. Al-Wassiti, David R. Thomas, Kylie M. Wagstaff, Stewart A. Fabb, David A. Jans, Angus P. Johnston, Colin W. Pouton
Published 2021-03-01

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells.

by Lindsay Lundberg, Chelsea Pinkham, Cynthia de la Fuente, Ashwini Brahms, Nazly Shafagati, Kylie M Wagstaff, David A Jans, Sharon Tamir, Kylene Kehn-Hall
Published 2016-11-01

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

by Sundy N. Y. Yang, Sarah C. Atkinson, Johanna E. Fraser, Chunxiao Wang, Belinda Maher, Noelia Roman, Jade K. Forwood, Kylie M. Wagstaff, Natalie A. Borg, David A. Jans
Published 2019-03-01

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

by Bikshapathi Jagga, Megan Edwards, Miriam Pagin, Kylie M. Wagstaff, David Aragão, Noelia Roman, Jeffrey D. Nanson, Shane R. Raidal, Nicole Dominado, Murray Stewart, David A. Jans, Gary R. Hime, Silvia K. Nicolis, Christopher F. Basler, Jade K. Forwood
Published 2021-01-01

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

by Hayley J Newton, Jaclyn S Pearson, Luminita Badea, Michelle Kelly, Mark Lucas, Gavan Holloway, Kylie M Wagstaff, Michelle A Dunstone, Joan Sloan, James C Whisstock, James B Kaper, Roy M Robins-Browne, David A Jans, Gad Frankel, Alan D Phillips, Barbara S Coulson, Elizabeth L Hartland
Published 2010-05-01