Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

by Stanciu, Monica, Lees, Jacqueline
Published 2020

Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation

by Danielian, Paul S., Lees, Jacqueline, Landman, A. S.
Published 2015

Inactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancer

by Bronson, R T, Parisi, Tiziana, Lees, Jacqueline
Published 2016

E2f4 and E2f5 are essential for the development of the male reproductive system

by Hess, Rex A., Lees, Jacqueline, Danielian, Paul S.
Published 2017

The Rb tumor suppressor regulates epithelial cell migration and polarity

by Parisi, Tiziana, Balsamo, Michele, Gertler, Frank, Lees, Jacqueline
Published 2020

The awakening of the CDK10/Cyclin M protein kinase

by Gamble, Carly, Colas, Pierre, Guen, Vincent, Lees, Jacqueline
Published 2017

BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance

by Ferretti, Roberta, Bhutkar, Arjun, McNamara, Molly C., Lees, Jacqueline
Published 2017

Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer

by Maynard, Mindy, Perret, C., Whyte, P., Ferretti, Roberta, Lees, Jacqueline, Hilgendorf, K. I.
Published 2015

E2F4 cooperates with pRB in the development of extra-embryonic tissues

by Lee, Eunice Y., Yuan, Tina L., Danielian, Paul S., West, Julie C., Lees, Jacqueline
Published 2012

Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology

by Perez, Dahlia E., Henle, Andrea M., Amsterdam, Adam, Hagen, Hannah R., Lees, Jacqueline A.
Published 2020

EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling

by Kröger, Cornelia, Ye, Xin, Guen, Vincent, Chavarria, Tony E, Weinberg, Robert A, Lees, Jacqueline
Published 2018

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers

by Zhang, GuangJun, Hoersch, Sebastian, Amsterdam, Adam, Whittaker, Charles A., Lees, Jacqueline, Hopkins, Nancy H.
Published 2014

Rb regulates fate choice and lineage commitment in vivo

by Calo, Eliezer, Quintero-Estades, Jose A., Danielian, Paul S., Nedelcu, Simona, Berman, Seth D., Lees, Jacqueline
Published 2012

Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects

by Lees, Jacqueline, Caron, Alicia M., Danielian, Paul S., West, Julie C., Stone, James R., Berman, Seth D.
Published 2010

Zebrafish Hagoromo mutants upregulate fgf8 post-embryonically and develop neuroblastoma

by Amsterdam, Adam, Lai, Kevin, Komisarczuk, Anna Z., Becker, Thomas S., Bronson, Roderick T., Hopkins, Nancy H., Lees, Jacqueline
Published 2012

Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein

by Ianari, Alessandra, Natale, Tiziana, Calo, Eliezer, Ferretti, Elisabetta, Alesse, Edoardo, Screpanti, Isabella, Haigis, Kevin M., Gulino, Alberto, Lees, Jacqueline
Published 2014

Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

by Percival, Stefanie M., Thomas, Holly R., Amsterdam, Adam, Carroll, Andrew J., Lees, Jacqueline, Yost, H. Joseph, Parant, John M.
Published 2015

Single-molecule transcript counting of stem-cell markers in the mouse intestine

by Itzkovitz, Shaul Shalev, Lyubimova, Anna, Blat, Irene C., Maynard, Mindy, van Es, Johan, Lees, Jacqueline, Jacks, Tyler E., Clevers, Hans, van Oudenaarden, Alexander
Published 2012

Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

by Mori, Munemasa, Mahoney, John E., Li, Huijun, Lu, Jining, Zhu, Xueliang, Cardoso, Wellington V., Hazan, Renin, Miller, Emily Sun Young, Lees, Jacqueline, Danielian, Paul S.
Published 2018

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

by Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R, Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A., Boutz, Paul, Patterson, Jesse C, Yaffe, Michael B, Hemann, Michael, Lees, Jacqueline, Braun, Christian Joerg, Sharp, Phillip A.
Published 2018