The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders

by Rob J. W. Arts, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea
Published 2018-02-01

Conceptualization of population-specific human functional immune-genomics projects to identify factors that contribute to variability in immune and infectious diseases

by Collins K. Boahen, Leo A.B. Joosten, Mihai G. Netea, Vinod Kumar
Published 2021-04-01

Innate Immune Recognition of Mycobacterium tuberculosis

by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel
Published 2011-01-01

An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo

by Marlies P. Noz, Adelina S. Plachokova, Esther M.M. Smeets, Erik H. J. G. Aarntzen, Siroon Bekkering, Prya Vart, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Niels P. Riksen
Published 2021-08-01

Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species.

by Teske Schoffelen, Maria-Teresa Illnait-Zaragozi, Leo A B Joosten, Mihai G Netea, Teun Boekhout, Jacques F Meis, Tom Sprong
Published 2013-01-01

Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides

by Michel Neidhart, Agnieszka Pajak, Katerina Laskari, Niels P. Riksen, Niels P. Riksen, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Mihai G. Netea, Mihai G. Netea, Esther Lutgens, Esther Lutgens, Eric S. G. Stroes, Adrian Ciurea, Oliver Distler, Mariam Grigorian, Emmanuel Karouzakis
Published 2019-04-01

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

by Noa Bossel Ben-Moshe, Shelly Hen-Avivi, Natalia Levitin, Dror Yehezkel, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Roi Avraham
Published 2019-07-01

IL-1beta processing in host defense: beyond the inflammasomes.

by Mihai G Netea, Anna Simon, Frank van de Veerdonk, Bart-Jan Kullberg, Jos W M Van der Meer, Leo A B Joosten
Published 2010-02-01

Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome.

by Theo S Plantinga, Esther van de Vosse, Angelique Huijbers, Mihai G Netea, Leo A B Joosten, Jan W A Smit, Romana T Netea-Maier
Published 2014-01-01

Circulating lipoproteins are a crucial component of host defense against invasive Salmonella typhimurium infection.

by Mihai G Netea, Leo A B Joosten, Monique Keuter, Frank Wagener, Anton F H Stalenhoef, Jos W M van der Meer, Bart Jan Kullberg
Published 2009-01-01

NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis

by Carlo Marchetti, Benjamin Swartzwelter, Marije I. Koenders, Tania Azam, Isak W. Tengesdal, Nick Powers, Dennis M. de Graaf, Charles A. Dinarello, Leo A. B. Joosten
Published 2018-08-01

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

by Marije Oosting, Hadewych Ter Hofstede, Patrick Sturm, Gosse J Adema, Bart-Jan Kullberg, Jos W M van der Meer, Mihai G Netea, Leo A B Joosten
Published 2011-01-01

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment

by Megan E. Roerink, Hans Knoop, Ewald M. Bronkhorst, Henk A. Mouthaan, Luuk J. A. C. Hawinkels, Leo A. B. Joosten, Jos W. M. van der Meer
Published 2017-12-01

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G

by Marloes van Splunter, Thijs L. J. van Osch, Sylvia Brugman, Huub F. J. Savelkoul, Leo A. B. Joosten, Mihai G. Netea, R. J. Joost van Neerven
Published 2018-09-01

Pro-inflammatory Monocyte Phenotype During Acute Progression of Cerebral Small Vessel Disease

by Marlies P. Noz, Annemieke ter Telgte, Kim Wiegertjes, Anil M. Tuladhar, Charlotte Kaffa, Simone Kersten, Simone Kersten, Siroon Bekkering, Charlotte D. C. C. van der Heijden, Alexander Hoischen, Alexander Hoischen, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Marco Duering, Marco Duering, Marco Duering, Frank-Erik de Leeuw, Niels P. Riksen
Published 2021-05-01

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents

by Xiang Zhang, Adil Mardinoglu, Adil Mardinoglu, Leo A. B. Joosten, Jan A. Kuivenhoven, Yang Li, Mihai G. Netea, Mihai G. Netea, Albert K. Groen, Albert K. Groen
Published 2018-02-01

TLR-3 is present in human adipocytes, but its signalling is not required for obesity-induced inflammation in adipose tissue in vivo.

by Dov B Ballak, Edwin J P van Asseldonk, Janna A van Diepen, Henry Jansen, Anneke Hijmans, Leo A B Joosten, Cees J Tack, Mihai G Netea, Rinke Stienstra
Published 2015-01-01

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression

by Isak W. Tengesdal, Isak W. Tengesdal, Alberto Dinarello, Alberto Dinarello, Nicholas E. Powers, Matthew A. Burchill, Leo A. B. Joosten, Carlo Marchetti, Charles A. Dinarello, Charles A. Dinarello
Published 2021-08-01

Prevalence and associated risk factors for Kaposi’s sarcoma among HIV-positive patients in a referral hospital in Northern Tanzania: a retrospective hospital-based study

by George P. Semango, Renard M. Charles, Consolata I. Swai, Alex Mremi, Patrick Amsi, Tolbert Sonda, Elichilia R. Shao, Daudi R. Mavura, Leo A. B. Joosten, Elingarami Sauli, Mramba Nyindo
Published 2018-12-01

Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis.

by Renoud J Marijnissen, Marije I Koenders, Frank L van de Veerdonk, John Dulos, Mihai G Netea, Annemieke M H Boots, Leo A B Joosten, Wim B van den Berg
Published 2012-01-01