Immunomodulation as Therapy for Fungal Infection: Are We Closer?

by Qi Hui Sam, Qi Hui Sam, Qi Hui Sam, Wen Shan Yew, Wen Shan Yew, Chaminda J. Seneviratne, Matthew Wook Chang, Matthew Wook Chang, Louis Yi Ann Chai, Louis Yi Ann Chai, Louis Yi Ann Chai, Louis Yi Ann Chai
Published 2018-07-01

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host

by Qi Hui Sam, Matthew Wook Chang, Louis Yi Ann Chai
Published 2017-02-01

Optimizing Outcomes in Immunocompromised Hosts: Understanding the Role of Immunotherapy in Invasive Fungal Diseases

by Sharada eRavikumar, Mar Soe eWin, Louis Yi Ann Chai
Published 2015-11-01

Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions

by Zixi Wang, Zixi Wang, Di Guan, Di Guan, Shu Wang, Louis Yi Ann Chai, Louis Yi Ann Chai, Shengli Xu, Shengli Xu, Kong-Peng Lam, Kong-Peng Lam
Published 2020-02-01

Lactobacillus Plantarum 108 Inhibits Streptococcus mutans and Candida albicans Mixed-Species Biofilm Formation

by Neha Srivastava, Kassapa Ellepola, Nityasri Venkiteswaran, Louis Yi Ann Chai, Tomoko Ohshima, Chaminda Jayampath Seneviratne
Published 2020-08-01

The Divergent Immunomodulatory Effects of Short Chain Fatty Acids and Medium Chain Fatty Acids

by Qi Hui Sam, Hua Ling, Wen Shan Yew, Zhaohong Tan, Sharada Ravikumar, Matthew Wook Chang, Louis Yi Ann Chai
Published 2021-06-01

The costs of an expanded screening criteria for COVID-19: A modelling study

by Jue Tao Lim, Borame L. Dickens, Alex R. Cook, Ai Leng Khoo, Yock Young Dan, Dale Andrew Fisher, Paul Anantharajah Tambyah, Louis Yi Ann Chai
Published 2020-11-01

Melioidosis, Singapore, 2003–2014

by Long Pang, Patrick N.A. Harris, Rachel L. Seiler, Peng Lim Ooi, Jeffrey Cutter, Kee Tai Goh, Alex R. Cook, Dale Fisher, Louis Yi Ann Chai
Published 2018-01-01

Association of Melioidosis Incidence with Rainfall and Humidity, Singapore, 2003–2012

by Xiang Liu, Long Pang, Siew Hoon Sim, Kee Tai Goh, Sharada Ravikumar, Mar Soe Win, Gladys Tan, Alex Richard Cook, Dale Fisher, Louis Yi Ann Chai
Published 2015-01-01

Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis

by Zhaohong Tan, Michelle Meng Huang Mok, Win Mar Soe, Thomas Paulraj Thamboo, Jessamine Geraldine Goh, Qi Hui Sam, Motomi Osato, Sharada Ravikumar, Louis Yi Ann Chai
Published 2021-08-01

Voriconazole or amphotericin B as primary therapy yields distinct early serum galactomannan trends related to outcomes in invasive aspergillosis.

by Louis Yi Ann Chai, Bart Jan Kullberg, Arul Earnest, Elizabeth M Johnson, Steven Teerenstra, Alieke G Vonk, Haran T Schlamm, Raoul Herbrecht, Mihai G Netea, Peter F Troke
Published 2014-01-01

Cost-Effectiveness of Serum Galactomannan Surveillance during Mould-Active Antifungal Prophylaxis

by Ai Leng Khoo, Ying Jiao Zhao, Glorijoy Shi En Tan, Monica Teng, Jenny Yap, Paul Anantharajah Tambyah, Chin Hin Ng, Boon Peng Lim, Louis Yi Ann Chai
Published 2021-05-01

Modelling lockdown and exit strategies for COVID-19 in Singapore

by Borame L. Dickens, Joel R. Koo, Jue Tao Lim, Minah Park, Sharon Quaye, Haoyang Sun, Yinxiaohe Sun, Rachael Pung, Annelies Wilder-Smith, Louis Yi Ann Chai, Vernon J. Lee, Alex R. Cook
Published 2020-08-01

Sulphonylurea usage in melioidosis is associated with severe disease and suppressed immune response.

by Xiang Liu, Geraldine Foo, Wan Peng Lim, Sharada Ravikumar, Siew Hoon Sim, Mar Soe Win, Jessamine Geraldine Goh, Joan Hui Juan Lim, Ying Hui Ng, Dale Fisher, Chin Meng Khoo, Gladys Tan, Louis Yi Ann Chai
Published 2014-04-01

Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis

by Win Mar Soe, Joan Hui Juan Lim, David L. Williams, Jessamine Geraldine Goh, Zhaohong Tan, Qi Hui Sam, Sanjay H. Chotirmall, Nur A’tikah Binte Mohamed Ali, Soo Chin Lee, Ju Ee Seet, Sharada Ravikumar, Louis Yi Ann Chai
Published 2020-10-01

Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore

by Gabriel Yan, Long Pang, Alex R. Cook, Hanley J. Ho, Mar Soe Win, Ai Leng Khoo, Joshua G.X. Wong, Chun Kiat Lee, Benedict Yan, Roland Jureen, Siew Seen Ho, David C. Lye, Paul A. Tambyah, Yee Sin Leo, Dale Fisher, Jolene Oon, Natasha Bagdasarian, Angela Chow, Nares Smitasin, Louis Yi Ann Chai
Published 2018-08-01

Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients

by Chek Meng Poh, Guillaume Carissimo, Bei Wang, Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Rhonda Sin-Ling Chee, Siew-Wai Fong, Nicholas Kim-Wah Yeo, Wen-Hsin Lee, Anthony Torres-Ruesta, Yee-Sin Leo, Mark I-Cheng Chen, Seow-Yen Tan, Louis Yi Ann Chai, Shirin Kalimuddin, Shirley Seah Gek Kheng, Siew-Yee Thien, Barnaby Edward Young, David C. Lye, Brendon John Hanson, Cheng-I Wang, Laurent Renia, Lisa F. P. Ng
Published 2020-06-01

Melioidosis in Singapore: Clinical, Veterinary, and Environmental Perspectives

by Siew Hoon Sim, Catherine Ee Ling Ong, Yunn Hwen Gan, Dongling Wang, Victor Wee Hong Koh, Yian Kim Tan, Michelle Su Yen Wong, Janet Seok Wei Chew, Sian Foong Ling, Brian Zi Yan Tan, Agnes Zhengyu Ye, Patrick Chuan Kiat Bay, Wai Kwan Wong, Charlene Judith Fernandez, Shangzhe Xie, Praveena Jayarajah, Tasha Tahar, Pei Yee Oh, Sonja Luz, Jaime Mei Fong Chien, Thuan Tong Tan, Louis Yi Ann Chai, Dale Fisher, Yichun Liu, Jimmy Jin Phang Loh, Gladys Gek Yen Tan
Published 2018-03-01

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

by Ser Hon Puah, Barnaby Edward Young, Po Ying Chia, Vui Kian Ho, Jiashen Loh, Roshni Sadashiv Gokhale, Seow Yen Tan, Duu Wen Sewa, Shirin Kalimuddin, Chee Keat Tan, Surinder K. M. S. Pada, Matthew Edward Cove, Louis Yi Ann Chai, Purnima Parthasarathy, Benjamin Choon Heng Ho, Jensen Jiansheng Ng, Li Min Ling, John A. Abisheganaden, Vernon J. M. Lee, Cher Heng Tan, Raymond T. P. Lin, Yee Sin Leo, David C. Lye, Tsin Wen Yeo, Singapore 2019 novel coronavirus outbreak research team
Published 2021-04-01