B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade.

by Katherine J Nicholas, Emily K Zern, Louise Barnett, Rita M Smith, Shelly L Lorey, Courtney A Copeland, Shanmugalakshmi Sadagopal, Spyros A Kalams
Published 2013-01-01

Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.

by Jennifer Currenti, Abha Chopra, Mina John, Shay Leary, Elizabeth McKinnon, Eric Alves, Mark Pilkinton, Rita Smith, Louise Barnett, Wyatt J McDonnell, Michaela Lucas, Francine Noel, Simon Mallal, Joseph A Conrad, Spyros A Kalams, Silvana Gaudieri
Published 2019-12-01

Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG.

by Shanmugalakshmi Sadagopal, Miriam Braunstein, Cynthia C Hager, Jie Wei, Alexandria K Daniel, Markian R Bochan, Ian Crozier, Nathaniel E Smith, Hiriam O Gates, Louise Barnett, Luc Van Kaer, James O Price, Timothy S Blackwell, Spyros A Kalams, Douglas S Kernodle
Published 2009-01-01

Increased Frequency of Memory CD4+ T-Cell Responses in Individuals With Previously Treated Extrapulmonary Tuberculosis

by Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Timothy R. Sterling, Timothy R. Sterling, Christina T. Fiske, Christina T. Fiske, Alexandre Almeida, Cynthia H. Nochowicz, Cynthia H. Nochowicz, Rita M. Smith, Rita M. Smith, Louise Barnett, Louise Barnett, Christian Warren, Christian Warren, Amondrea Blackman, Amondrea Blackman, Jose Roberto Lapa e Silva, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Spyros A. Kalams, Spyros A. Kalams
Published 2020-12-01

Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome

by Michaela Lucas, Pooja Deshpande, Ian James, Andri Rauch, Katja Pfafferott, Elouise Gaylard, Shahzma Merani, Anne Plauzolles, Andrew Lucas, Wyatt McDonnell, Spyros Kalams, Mark Pilkinton, Cody Chastain, Louise Barnett, Amy Prosser, Simon Mallal, Karen Fitzmaurice, Heidi Drummer, M. Azim Ansari, Vincent Pedergnana, Ellie Barnes, Mina John, Dermot Kelleher, Paul Klenerman, Silvana Gaudieri
Published 2018-05-01

Adipose Tissue in Persons With HIV Is Enriched for CD4+ T Effector Memory and T Effector Memory RA+ Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression W...

by Celestine N. Wanjalla, Celestine N. Wanjalla, Wyatt J. McDonnell, Wyatt J. McDonnell, Wyatt J. McDonnell, Wyatt J. McDonnell, Louise Barnett, Joshua D. Simmons, Briana D. Furch, Briana D. Furch, Morgan C. Lima, Morgan C. Lima, Beverly O. Woodward, Beverly O. Woodward, Run Fan, Ye Fei, Paxton G. Baker, Ramesh Ram, Mark A. Pilkinton, Mark A. Pilkinton, Mona Mashayekhi, Mona Mashayekhi, Nancy J. Brown, Simon A. Mallal, Simon A. Mallal, Simon A. Mallal, Simon A. Mallal, Simon A. Mallal, Spyros A. Kalams, Spyros A. Kalams, Spyros A. Kalams, John R. Koethe, John R. Koethe
Published 2019-03-01