Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non‐small cell lung cancer

by Hiroyuki Sayama, Diana Marcantonio, Takeyuki Nagashima, Masashi Shimazaki, Tsuyoshi Minematsu, Joshua F Apgar, John M. Burke, Lucia Wille, Yasuhisa Nagasaka, Daniel C. Kirouac
Published 2021-08-01

Quantitative modeling predicts competitive advantages of a next generation anti‐NKG2A monoclonal antibody over monalizumab for the treatment of cancer

by Phillip Spinosa, Monika Musial‐Siwek, Marc Presler, Alison Betts, Emily Rosentrater, Janice Villali, Lucia Wille, Yang Zhao, Tom McCaughtry, Kalyanasundaram Subramanian, Hanlan Liu
Published 2021-03-01

A systems pharmacology model for gene therapy in sickle cell disease

by Bo Zheng, Lucia Wille, Karsten Peppel, David Hagen, Andrew Matteson, Jeffrey Ahlers, James Schaff, Fei Hua, Theresa Yuraszeck, Enoch Cobbina, Joshua F. Apgar, John M. Burke, John Roberts, Raibatak Das
Published 2021-07-01