A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.

by Andrea Wirsing, Sabine Senkel, Ludger Klein-Hitpass, Gerhart U Ryffel
Published 2011-01-01

Aging of Xenopus tropicalis eggs leads to deadenylation of a specific set of maternal mRNAs and loss of developmental potential.

by Anna Kosubek, Ludger Klein-Hitpass, Katrin Rademacher, Bernhard Horsthemke, Gerhart U Ryffel
Published 2010-01-01

Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures

by Hans-Ulrich Steinau, Heinz-Herbert Homann, Jörg Hauser, Michael Chromik, Oliver Müller, Ludger Klein-Hitpass, Adrien Daigeler, Marcus Lehnhardt
Published 2008-10-01

Epitope-Specific Tolerance Modes Differentially Specify Susceptibility to Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis

by Lei Wang, Julia Winnewisser, Christine Federle, Gregor Jessberger, Klaus-Armin Nave, Hauke B. Werner, Bruno Kyewski, Ludger Klein, Maria Hinterberger
Published 2017-11-01

Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.

by Maher Hanoun, Lewin Eisele, Masako Suzuki, John M Greally, Andreas Hüttmann, Semra Aydin, René Scholtysik, Ludger Klein-Hitpass, Ulrich Dührsen, Jan Dürig
Published 2012-01-01

Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.

by Astrid Liedert, Viktoria Röntgen, Thorsten Schinke, Peggy Benisch, Regina Ebert, Franz Jakob, Ludger Klein-Hitpass, Jochen K Lennerz, Michael Amling, Anita Ignatius
Published 2014-01-01

A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia

by Alexa N. Lauer, Rene Scholtysik, Andreas Beineke, Christoph Georg Baums, Kristin Klose, Peter Valentin-Weigand, Hiroshi Ishikawa, Horst Schroten, Ludger Klein-Hitpass, Christian Schwerk
Published 2021-03-01

Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia

by Patricia Johansson, Laura Dierichs, Ludger Klein-Hitpass, Anke K. Bergmann, Michael Möllmann, Sascha Menninger, Peter Habenberger, Bert Klebl, Jens T. Siveke, Ulrich Dührsen, Axel Choidas, Jan Dürig
Published 2020-10-01

Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing

by Patricia Johansson, Ludger Klein-Hitpass, Bettina Budeus, Matthias Kuhn, Chris Lauber, Michael Seifert, Ingo Roeder, Roman Pförtner, Martin Stuschke, Ulrich Dührsen, Anja Eckstein, Jan Dürig, Ralf Küppers
Published 2020-04-01

Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression.

by Stefanie Jeruschke, Kay Jeruschke, Andrew DiStasio, Sinem Karaterzi, Anja K Büscher, Perihan Nalbant, Ludger Klein-Hitpass, Peter F Hoyer, Jürgen Weiss, Rolf W Stottmann, Stefanie Weber
Published 2015-01-01

The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.

by Peggy Benisch, Tatjana Schilling, Ludger Klein-Hitpass, Sönke P Frey, Lothar Seefried, Nadja Raaijmakers, Melanie Krug, Martina Regensburger, Sabine Zeck, Thorsten Schinke, Michael Amling, Regina Ebert, Franz Jakob
Published 2012-01-01

Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia.

by Maria Göbel, Lewin Eisele, Michael Möllmann, Andreas Hüttmann, Patricia Johansson, René Scholtysik, Manuela Bergmann, Raymonde Busch, Hartmut Döhner, Michael Hallek, Till Seiler, Stephan Stilgenbauer, Ludger Klein-Hitpass, Ulrich Dührsen, Jan Dürig
Published 2013-01-01

Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function

by Christopher Schröder, Elsa Leitão, Stefan Wallner, Gerd Schmitz, Ludger Klein-Hitpass, Anupam Sinha, Karl-Heinz Jöckel, Stefanie Heilmann-Heimbach, Per Hoffmann, Markus M. Nöthen, Michael Steffens, Peter Ebert, Sven Rahmann, Bernhard Horsthemke
Published 2017-07-01

Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation

by Matouš Vobořil, Tomáš Brabec, Jan Dobeš, Iva Šplíchalová, Jiří Březina, Adéla Čepková, Martina Dobešová, Aigerim Aidarova, Jan Kubovčiak, Oksana Tsyklauri, Ondřej Štěpánek, Vladimír Beneš, Radislav Sedláček, Ludger Klein, Michal Kolář, Dominik Filipp
Published 2020-05-01

Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma tr...

by Stephanie T. Jünger, Martin Mynarek, Inken Wohlers, Evelyn Dörner, Anja zur Mühlen, Natalia Velez-Char, Katja von Hoff, Stefan Rutkowski, Monika Warmuth-Metz, Rolf-Dieter Kortmann, Beate Timmermann, Sven Rahmann, Ludger Klein-Hitpass, Andre O. von Bueren, Torsten Pietsch
Published 2019-11-01

Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7

by Bettina Wöchtl, Florian Gunzer, Wilhelm Gerner, Hagen Gasse, Michaela Koch, Zoltán Bagó, Martin Ganter, Herbert Weissenböck, Nora Dinhopl, Sina M. Coldewey, Alexandra von Altrock, Karl-Heinz Waldmann, Armin Saalmüller, Kurt Zimmermann, Jörg Steinmann, Jan Kehrmann, Ludger Klein-Hitpass, Jochen Blom, Ralf Ehricht, Ines Engelmann, Isabel Hennig-Pauka
Published 2017-05-01

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions

by Antje Sucker, Fang Zhao, Natalia Pieper, Christina Heeke, Raffaela Maltaner, Nadine Stadtler, Birgit Real, Nicola Bielefeld, Sebastian Howe, Benjamin Weide, Ralf Gutzmer, Jochen Utikal, Carmen Loquai, Helen Gogas, Ludger Klein-Hitpass, Michael Zeschnigk, Astrid M. Westendorf, Mirko Trilling, Susanne Horn, Bastian Schilling, Dirk Schadendorf, Klaus G. Griewank, Annette Paschen
Published 2017-05-01

Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia

by Maurizio Mangolini, Frederik Götte, Andrew Moore, Tim Ammon, Madlen Oelsner, Gloria Lutzny-Geier, Ludger Klein-Hitpass, James C. Williamson, Paul J. Lehner, Jan Dürig, Michael Möllmann, Lívia Rásó-Barnett, Katherine Hughes, Antonella Santoro, Simón Méndez-Ferrer, Robert A. J. Oostendorp, Ursula Zimber-Strobl, Christian Peschel, Daniel J. Hodson, Marc Schmidt-Supprian, Ingo Ringshausen
Published 2018-09-01