What makes the hepatitis C virus evolve?

by Thomas R O'Brien, Rune Hartmann, Ludmila Prokunina-Olsson
Published 2019-09-01

Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms.

by Hye Kyung Kim, Ludmila Prokunina-Olsson, Stephen J Chanock
Published 2012-01-01

Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes.

by Ludmila Prokunina-Olsson, Lee M Kaplan, Eric E Schadt, Francis S Collins
Published 2009-09-01

Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4).

by Felix M Key, Benjamin Peter, Megan Y Dennis, Emilia Huerta-Sánchez, Wei Tang, Ludmila Prokunina-Olsson, Rasmus Nielsen, Aida M Andrés
Published 2014-10-01

A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences

by Daniel Svensson, Matilda Rentoft, Anna M. Dahlin, Emma Lundholm, Pall I. Olason, Andreas Sjödin, Carin Nylander, Beatrice S. Melin, Johan Trygg, Erik Johansson, Ludmila Prokunina-Olsson
Published 2020-01-01

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

by Megan Y Dennis, Silvia Paracchini, Thomas S Scerri, Ludmila Prokunina-Olsson, Julian C Knight, Richard Wade-Martins, Penny Coggill, Stephan Beck, Eric D Green, Anthony P Monaco
Published 2009-03-01

A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.

by Kerstin B Meyer, Ana-Teresa Maia, Martin O'Reilly, Maya Ghoussaini, Radhika Prathalingam, Patricia Porter-Gill, Stefan Ambs, Ludmila Prokunina-Olsson, Jason Carroll, Bruce A J Ponder
Published 2011-07-01

Vitamin D Status and Virologic Response to HCV Therapy in the HALT-C and VIRAHEP-C Trials.

by Erikka Loftfield, Thomas R O'Brien, Ruth M Pfeiffer, Charles D Howell, Ron Horst, Ludmila Prokunina-Olsson, Stephanie J Weinstein, Demetrius Albanes, Timothy R Morgan, Neal D Freedman
Published 2016-01-01

Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity

by A. Rouf Banday, Olusegun O. Onabajo, Seraph Han-Yin Lin, Adeola Obajemu, Joselin M. Vargas, Krista A. Delviks-Frankenberry, Philippe Lamy, Ariunaa Bayanjargal, Clara Zettelmeyer, Oscar Florez-Vargas, Vinay K. Pathak, Lars Dyrskjøt, Ludmila Prokunina-Olsson
Published 2021-03-01

Interferon Lambda 4 Genotype Is Not Associated with Recurrence of Oral or Genital Herpes.

by Krystle A Lang Kuhs, Mark H Kuniholm, Ruth M Pfeiffer, Sabrina Chen, Seema Desai, Brian R Edlin, Marion G Peters, Michael Plankey, Gerald B Sharp, Howard D Strickler, Maria C Villacres, Thomas C Quinn, Stephen J Gange, Ludmila Prokunina-Olsson, Ruth M Greenblatt, Thomas R O'Brien
Published 2015-01-01

Intracellular Accumulation of IFN-λ4 Induces ER Stress and Results in Anti-Cirrhotic but Pro-HCV Effects

by Olusegun O. Onabajo, Fang Wang, Mei-Hsuan Lee, Oscar Florez-Vargas, Adeola Obajemu, Chizu Tanikawa, Joselin M. Vargas, Shu-Fen Liao, Shu-Fen Liao, Ci Song, Yu-Han Huang, Chen-Yang Shen, A. Rouf Banday, Thomas R. O’Brien, Zhibin Hu, Koichi Matsuda, Ludmila Prokunina-Olsson
Published 2021-08-01

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

by Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Anna-Leigh Brown, Alexander Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David E. Kleiner, Stephen M. Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
Published 2019-03-01

Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studiesResearch...

by Andriy Derkach, Isaac Otim, Ruth M. Pfeiffer, Olusegun O. Onabajo, Ismail D. Legason, Hadijah Nabalende, Martin D. Ogwang, Patrick Kerchan, Ambrose O. Talisuna, Leona W. Ayers, Steven J. Reynolds, Francis Nkrumah, Janet Neequaye, Kishor Bhatia, Thor G. Theander, Ludmila Prokunina-Olsson, Louise Turner, James J. Goedert, Thomas Lavstsen, Sam M. Mbulaiteye
Published 2019-01-01

Evaluating the Causal Link Between Malaria Infection and Endemic Burkitt Lymphoma in Northern Uganda: A Mendelian Randomization Study

by Ismail D. Legason, Ruth M. Pfeiffer, Krizia-Ivana Udquim, Andrew W. Bergen, Mateus H. Gouveia, Samuel Kirimunda, Isaac Otim, Eric Karlins, Patrick Kerchan, Hadijah Nabalende, Ariunaa Bayanjargal, Benjamin Emmanuel, Paul Kagwa, Ambrose O. Talisuna, Kishor Bhatia, Meredith Yeager, Robert J. Biggar, Leona W. Ayers, Steven J. Reynolds, James J. Goedert, Martin D. Ogwang, Joseph F. Fraumeni, Jr, Ludmila Prokunina-Olsson, Sam M. Mbulaiteye
Published 2017-11-01

Immune gene expression profiling reveals heterogeneity in luminal breast tumors

by Bin Zhu, Lap Ah Tse, Difei Wang, Hela Koka, Tongwu Zhang, Mustapha Abubakar, Priscilla Lee, Feng Wang, Cherry Wu, Koon Ho Tsang, Wing-cheong Chan, Sze Hong Law, Mengjie Li, Wentao Li, Suyang Wu, Zhiguang Liu, Bixia Huang, Han Zhang, Eric Tang, Zhengyan Kan, Soohyeon Lee, Yeon Hee Park, Seok Jin Nam, Mingyi Wang, Xuezheng Sun, Kristine Jones, Bin Zhu, Amy Hutchinson, Belynda Hicks, Ludmila Prokunina-Olsson, Jianxin Shi, Montserrat Garcia-Closas, Stephen Chanock, Xiaohong R. Yang
Published 2019-12-01

Genetic signatures of gene flow and malaria-driven natural selection in sub-Saharan populations of the "endemic Burkitt Lymphoma belt".

by Mateus H Gouveia, Andrew W Bergen, Victor Borda, Kelly Nunes, Thiago P Leal, Martin D Ogwang, Edward D Yeboah, James E Mensah, Tobias Kinyera, Isaac Otim, Hadijah Nabalende, Ismail D Legason, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Patrick Kerchan, Kishor Bhatia, Steven J Reynolds, Richard B Birtwum, Andrew A Adjei, Yao Tettey, Evelyn Tay, Robert Hoover, Ruth M Pfeiffer, Robert J Biggar, James J Goedert, Ludmila Prokunina-Olsson, Michael Dean, Meredith Yeager, M Fernanda Lima-Costa, Ann W Hsing, Sarah A Tishkoff, Stephen J Chanock, Eduardo Tarazona-Santos, Sam M Mbulaiteye
Published 2019-03-01

Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background.

by Idan Menashe, Jonine D Figueroa, Montserrat Garcia-Closas, Nilanjan Chatterjee, Nuria Malats, Antoni Picornell, Dennis Maeder, Qi Yang, Ludmila Prokunina-Olsson, Zhaoming Wang, Francisco X Real, Kevin B Jacobs, Dalsu Baris, Michael Thun, Demetrius Albanes, Mark P Purdue, Manolis Kogevinas, Amy Hutchinson, Yi-Ping Fu, Wei Tang, Laurie Burdette, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina García-Closas, Josep Lloreta, Alison Johnson, Molly Schwenn, Alan Schned, Gerald Andriole, Amanda Black, Eric J Jacobs, Ryan W Diver, Susan M Gapstur, Stephanie J Weinstein, Jarmo Virtamo, Neil E Caporaso, Maria Teresa Landi, Joseph F Fraumeni, Stephen J Chanock, Debra T Silverman, Nathaniel Rothman
Published 2012-01-01

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.

by Hisani N Horne, Charles C Chung, Han Zhang, Kai Yu, Ludmila Prokunina-Olsson, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, John L Hopper, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, Kenneth Muir, Artitaya Lophatananon, Peter A Fasching, Matthias W Beckmann, Olivia Fletcher, Nichola Johnson, Elinor J Sawyer, Ian Tomlinson, Barbara Burwinkel, Frederik Marme, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Henrik Flyger, Javier Benitez, Anna González-Neira, Hoda Anton-Culver, Susan L Neuhausen, Hermann Brenner, Volker Arndt, Alfons Meindl, Rita K Schmutzler, Hiltrud Brauch, Ute Hamann, Heli Nevanlinna, Sofia Khan, Keitaro Matsuo, Hiroji Iwata, Thilo Dörk, Natalia V Bogdanova, Annika Lindblom, Sara Margolin, Arto Mannermaa, Veli-Matti Kosma, Georgia Chenevix-Trench, kConFab/AOCS Investigators, Anna H Wu, David Ven den Berg, Ann Smeets, Hui Zhao, Jenny Chang-Claude, Anja Rudolph, Paolo Radice, Monica Barile, Fergus J Couch, Celine Vachon, Graham G Giles, Roger L Milne, Christopher A Haiman, Loic Le Marchand, Mark S Goldberg, Soo H Teo, Nur A M Taib, Vessela Kristensen, Anne-Lise Borresen-Dale, Wei Zheng, Martha Shrubsole, Robert Winqvist, Arja Jukkola-Vuorinen, Irene L Andrulis, Julia A Knight, Peter Devilee, Caroline Seynaeve, Montserrat García-Closas, Kamila Czene, Hatef Darabi, Antoinette Hollestelle, John W M Martens, Jingmei Li, Wei Lu, Xiao-Ou Shu, Angela Cox, Simon S Cross, William Blot, Qiuyin Cai, Mitul Shah, Craig Luccarini, Caroline Baynes, Patricia Harrington, Daehee Kang, Ji-Yeob Choi, Mikael Hartman, Kee Seng Chia, Maria Kabisch, Diana Torres, Anna Jakubowska, Jan Lubinski, Suleeporn Sangrajrang, Paul Brennan, Susan Slager, Drakoulis Yannoukakos, Chen-Yang Shen, Ming-Feng Hou, Anthony Swerdlow, Nick Orr, Jacques Simard, Per Hall, Paul D P Pharoah, Douglas F Easton, Stephen J Chanock, Alison M Dunning, Jonine D Figueroa
Published 2016-01-01

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

by Mitchell J. Machiela, Weiyin Zhou, Eric Karlins, Joshua N. Sampson, Neal D. Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B. Jacobs, Christian C. Abnet, Melinda C. Aldrich, Christopher Amos, Laufey T. Amundadottir, Alan A. Arslan, Laura E. Beane-Freeman, Sonja I. Berndt, Amanda Black, William J. Blot, Cathryn H. Bock, Paige M. Bracci, Louise A. Brinton, H Bas Bueno-de-Mesquita, Laurie Burdett, Julie E. Buring, Mary A. Butler, Federico Canzian, Tania Carreón, Kari G. Chaffee, I-Shou Chang, Nilanjan Chatterjee, Chu Chen, Constance Chen, Kexin Chen, Charles C. Chung, Linda S. Cook, Marta Crous Bou, Michael Cullen, Faith G. Davis, Immaculata De Vivo, Ti Ding, Jennifer Doherty, Eric J. Duell, Caroline G. Epstein, Jin-Hu Fan, Jonine D. Figueroa, Joseph F. Fraumeni, Christine M. Friedenreich, Charles S. Fuchs, Steven Gallinger, Yu-Tang Gao, Susan M. Gapstur, Montserrat Garcia-Closas, Mia M. Gaudet, J. Michael Gaziano, Graham G. Giles, Elizabeth M. Gillanders, Edward L. Giovannucci, Lynn Goldin, Alisa M. Goldstein, Christopher A. Haiman, Goran Hallmans, Susan E. Hankinson, Curtis C. Harris, Roger Henriksson, Elizabeth A. Holly, Yun-Chul Hong, Robert N. Hoover, Chao A. Hsiung, Nan Hu, Wei Hu, David J. Hunter, Amy Hutchinson, Mazda Jenab, Christoffer Johansen, Kay-Tee Khaw, Hee Nam Kim, Yeul Hong Kim, Young Tae Kim, Alison P. Klein, Robert Klein, Woon-Puay Koh, Laurence N. Kolonel, Charles Kooperberg, Peter Kraft, Vittorio Krogh, Robert C. Kurtz, Andrea LaCroix, Qing Lan, Maria Teresa Landi, Loic Le Marchand, Donghui Li, Xiaolin Liang, Linda M. Liao, Dongxin Lin, Jianjun Liu, Jolanta Lissowska, Lingeng Lu, Anthony M. Magliocco, Nuria Malats, Keitaro Matsuo, Lorna H. McNeill, Robert R. McWilliams, Beatrice S. Melin, Lisa Mirabello, Lee Moore, Sara H. Olson, Irene Orlow, Jae Yong Park, Ana Patiño-Garcia, Beata Peplonska, Ulrike Peters, Gloria M. Petersen, Loreall Pooler, Jennifer Prescott, Ludmila Prokunina-Olsson, Mark P. Purdue, You-Lin Qiao, Preetha Rajaraman, Francisco X. Real, Elio Riboli, Harvey A. Risch, Benjamin Rodriguez-Santiago, Avima M. Ruder, Sharon A. Savage, Fredrick Schumacher, Ann G. Schwartz, Kendra L. Schwartz, Adeline Seow, Veronica Wendy Setiawan, Gianluca Severi, Hongbing Shen, Xin Sheng, Min-Ho Shin, Xiao-Ou Shu, Debra T. Silverman, Margaret R. Spitz, Victoria L. Stevens, Rachael Stolzenberg-Solomon, Daniel Stram, Ze-Zhong Tang, Philip R. Taylor, Lauren R. Teras, Geoffrey S. Tobias, David Van Den Berg, Kala Visvanathan, Sholom Wacholder, Jiu-Cun Wang, Zhaoming Wang, Nicolas Wentzensen, William Wheeler, Emily White, John K. Wiencke, Brian M. Wolpin, Maria Pik Wong, Chen Wu, Tangchun Wu, Xifeng Wu, Yi-Long Wu, Jay S. Wunder, Lucy Xia, Hannah P. Yang, Pan-Chyr Yang, Kai Yu, Krista A. Zanetti, Anne Zeleniuch-Jacquotte, Wei Zheng, Baosen Zhou, Regina G. Ziegler, Luis A. Perez-Jurado, Neil E. Caporaso, Nathaniel Rothman, Margaret Tucker, Michael C. Dean, Meredith Yeager, Stephen J. Chanock
Published 2016-06-01