Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis

by Finn Sellebjerg, Diego Cadavid, Deborah Steiner, Luisa Maria Villar, Richard Reynolds, Daniel Mikol
Published 2016-01-01

Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis

by Leyre Mestre, Leyre Mestre, Francisco Javier Carrillo-Salinas, Miriam Mecha, Miriam Mecha, Ana Feliú, Ana Feliú, Carmen Espejo, Carmen Espejo, Carmen Espejo, José Carlos Álvarez-Cermeño, José Carlos Álvarez-Cermeño, Luisa María Villar, Luisa María Villar, Carmen Guaza, Carmen Guaza
Published 2019-06-01

Whole-Transcriptome Analysis in Peripheral Blood Mononuclear Cells from Patients with Lipid-Specific Oligoclonal IgM Band Characterization Reveals Two Circular RNAs and Two Linear...

by Leire Iparraguirre, Danel Olaverri, Telmo Blasco, Lucía Sepúlveda, Tamara Castillo-Triviño, Mercedes Espiño, Lucienne Costa-Frossard, Álvaro Prada, Luisa María Villar, David Otaegui, Maider Muñoz-Culla
Published 2020-11-01

How oral probiotics affect the severity of an experimental model of progressive multiple sclerosis? Bringing commensal bacteria into the neurodegenerative process

by Leyre Mestre, Francisco J. Carrillo-Salinas, Ana Feliú, Miriam Mecha, Graciela Alonso, Carmen Espejo, Laura Calvo-Barreiro, José L. Luque-García, Héctor Estevez, Luisa María Villar, Carmen Guaza
Published 2020-11-01

Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

by María Muñoz-San Martín, Gemma Reverter, Rene Robles-Cedeño, Maria Buxò, Francisco José Ortega, Imma Gómez, Jordi Tomàs-Roig, Naiara Celarain, Luisa María Villar, Hector Perkal, José Manuel Fernández-Real, Ester Quintana, Lluís Ramió-Torrentà
Published 2019-11-01

Adaptive Features of Natural Killer Cells in Multiple Sclerosis

by Antía Moreira, Antía Moreira, Antía Moreira, Elisenda Alari-Pahissa, Elvira Munteis, Andrea Vera, Ana Zabalza, Mireia Llop, Noelia Villarrubia, Marcel Costa-García, Roberto Álvarez-Lafuente, Luisa María Villar, Miguel López-Botet, Miguel López-Botet, Jose E. Martínez-Rodríguez
Published 2019-10-01

Low serum neurofilament light chain values identify optimal responders to dimethyl fumarate in multiple sclerosis treatment

by Paulette Esperanza Walo-Delgado, Susana Sainz de la Maza, Noelia Villarrubia, Enric Monreal, Silvia Medina, Mercedes Espiño, José Ignacio Fernández-Velasco, Eulalia Rodríguez-Martín, Ernesto Roldán, Daniel Lourido, Alfonso Muriel, Jaime Masjuan-Vallejo, Lucienne Costa-Frossard, Luisa María Villar
Published 2021-04-01

Herpesvirus Antibodies, Vitamin D and Short-Chain Fatty Acids: Their Correlation with Cell Subsets in Multiple Sclerosis Patients and Healthy Controls

by Maria Inmaculada Dominguez-Mozo, Silvia Perez-Perez, Noelia Villarrubia, Lucienne Costa-Frossard, Jose Ignacio Fernandez-Velasco, Isabel Ortega-Madueño, Maria Angel Garcia-Martinez, Estefania Garcia-Calvo, Hector Estevez, Jose Luis Luque Garcia, Maria Josefa Torrejon, Rafael Arroyo, Luisa Maria Villar, Roberto Alvarez-Lafuente
Published 2021-01-01

A New Risk Variant for Multiple Sclerosis at 11q23.3 <i>Locus</i> Is Associated with Expansion of <i>CXCR5+</i> Circulating Regulatory T Cells

by Elia Gil-Varea, Maria Fedetz, Herena Eixarch, Nino Spataro, Luisa María Villar, Elena Urcelay, Albert Saiz, Óscar Fernández, Laura Leyva, Lluís Ramió-Torrentà, Koen Vandenbroeck, David Otaegui, Tamara Castillo-Triviño, Guillermo Izquierdo, Sunny Malhotra, Elena Bosch, Arcadi Navarro, Antonio Alcina, Xavier Montalban, Fuencisla Matesanz, Manuel Comabella
Published 2020-02-01

Evolution of antibody titres against Epstein–Barr virus and human herpesvirus 6A/B and expression of multiple sclerosis-associated retrovirus in the serum of pregnant multiple scle...

by Silvia Pérez-Pérez, Juan Pablo Cuello, Marisa Martínez-Ginés, Beatriz Pardo-Rodríguez, José Manuel García-Domínguez, María Inmaculada Domínguez-Mozo, Alberto Lozano-Ros, María Ángel García-Martínez, Yolanda Higueras, Ariana Meldaña-Rivera, Haydee Goicochea-Briceño, Amalia Tejeda-Velarde, Jose Ignacio Fernández-Velasco, Silvia Medina, Rafael Arroyo, Luisa María Villar, Roberto Álvarez-Lafuente
Published 2021-04-01

Role of B Cell Profile for Predicting Secondary Autoimmunity in Patients Treated With Alemtuzumab

by Paulette Esperanza Walo-Delgado, Enric Monreal, Silvia Medina, Ester Quintana, Susana Sainz de la Maza, José Ignacio Fernández-Velasco, Paloma Lapuente, Manuel Comabella, Lluis Ramió-Torrentà, Xavier Montalban, Luciana Midaglia, Noelia Villarrubia, Angela Carrasco-Sayalero, Eulalia Rodríguez-Martín, Ernesto Roldán, José Meca-Lallana, Roberto Alvarez-Lafuente, Jaime Masjuan, Lucienne Costa-Frossard, Luisa Maria Villar
Published 2021-10-01

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis

by Carmen Picón, Carmen Picón, Amalia Tejeda-Velarde, José Ignacio Fernández-Velasco, Manuel Comabella, Roberto Álvarez-Lafuente, Ester Quintana, Susana Sainz de la Maza, Enric Monreal, Noelia Villarrubia, José Carlos Álvarez-Cermeño, María Inmaculada Domínguez-Mozo, Lluís Ramió-Torrentà, Eulalia Rodríguez-Martín, Ernesto Roldán, Yolanda Aladro, Silvia Medina, Mercedes Espiño, Jaime Masjuan, Clara Matute-Blanch, Marta Muñoz-San Martín, Carmen Espejo, Carmen Guaza, Alfonso Muriel, Lucienne Costa-Frossard, Luisa María Villar
Published 2021-07-01