Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson’s disease

by Luisa Seguella, Giovanni Sarnelli, Giuseppe Esposito
Published 2020-01-01

S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells

by Luisa Seguella, Riccardo Capuano, Mirella Pesce, Giuseppe Annunziata, Marcella Pesce, Barbara de Conno, Giovanni Sarnelli, Laura Aurino, Giuseppe Esposito
Published 2019-07-01

Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional DyspepsiaSummary

by Giovanni Sarnelli, Marcella Pesce, Luisa Seguella, Jie Lu, Eleonora Efficie, Jan Tack, Fatima Domenica Elisa De Palma, Alessandra D’Alessandro, Giuseppe Esposito
Published 2021-01-01

Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macroph...

by Alessandro Del Re, Chiara Corpetti, Marcella Pesce, Luisa Seguella, Luca Steardo, Irene Palenca, Sara Rurgo, Barbara De Conno, Giovanni Sarnelli, Giuseppe Esposito
Published 2021-09-01

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia

by Giovanni Sarnelli, Luisa Seguella, Marcella Pesce, Jie Lu, Stefano Gigli, Eugenia Bruzzese, Roberta Lattanzi, Alessandra D’Alessandro, Rosario Cuomo, Luca Steardo, Giuseppe Esposito
Published 2018-03-01

Engineered <i>Lactobacillus paracasei</i> Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice

by Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Jie Lu, Chiara Corpetti, Alessandro Del Re, Fatima Domenica Elisa De Palma, Giovanni Esposito, Walter Sanseverino, Giovanni Sarnelli
Published 2021-03-01

HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system

by Giuseppe Esposito, Elena Capoccia, Stefano Gigli, Marcella Pesce, Eugenia Bruzzese, Alessandra D’Alessandro, Carla Cirillo, Alessandro di Cerbo, Rosario Cuomo, Luisa Seguella, Luca Steardo, Giovanni Sarnelli
Published 2017-08-01

High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors

by Luisa Seguella, Mirella Pesce, Riccardo Capuano, Fabrizio Casano, Marcella Pesce, Chiara Corpetti, Martina Vincenzi, Daniela Maftei, Roberta Lattanzi, Alessandro Del Re, Giovanni Sarnelli, Brian D. Gulbransen, Giuseppe Esposito
Published 2021-05-01

A Palmitoylethanolamide Producing Lactobacillus paracasei Improves Clostridium difficile Toxin A-Induced Colitis

by Giuseppe Esposito, Giuseppe Esposito, Chiara Corpetti, Marcella Pesce, Luisa Seguella, Giuseppe Annunziata, Alessandro Del Re, Martina Vincenzi, Roberta Lattanzi, Jie Lu, Walter Sanseverino, Giovanni Sarnelli, Giovanni Sarnelli, Giovanni Sarnelli
Published 2021-04-01

Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activate...

by Giovanni Sarnelli, Alessandra D'Alessandro, Teresa Iuvone, Elena Capoccia, Stefano Gigli, Marcella Pesce, Luisa Seguella, Nicola Nobile, Giovanni Aprea, Francesco Maione, Giovanni Domenico de Palma, Rosario Cuomo, Luca Steardo, Giuseppe Esposito
Published 2016-01-01