Biomarkers for type 2 diabetes

by Markku Laakso
Published 2019-09-01

Effect of lifestyle intervention on the risk of incident diabetes in individuals with impaired fasting glucose and low or high genetic risk for the development of type 2 diabetes i...

by Ursula Schwab, Maria Lankinen, Markku Laakso
Published 2021-09-01

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

by Jussi Pihlajamäki, Helena Gylling, Tatu A. Miettinen, Markku Laakso
Published 2004-03-01

Association of C-Reactive Protein, Interleukin-1 Receptor Antagonist and Adiponectin with the Metabolic Syndrome

by Esko Kumpusalo, Hannu Kautiainen, Mauno Vanhala, Juha Saltevo, Markku Laakso
Published 2007-01-01

Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men.

by Jagadish Vangipurapu, Alena Stančáková, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso
Published 2015-01-01

Finnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the ME...

by Maria Fizelova, Raimo Jauhiainen, Alena Stančáková, Johanna Kuusisto, Markku Laakso
Published 2016-01-01

Gender Differences Relating to Metabolic Syndrome and Proinflammation in Finnish Subjects with Elevated Blood Pressure

by Tiina Ahonen, Juha Saltevo, Markku Laakso, Hannu Kautiainen, Esko Kumpusalo, Mauno Vanhala
Published 2009-01-01

Reverse GWAS: Using genetics to identify and model phenotypic subtypes.

by Andy Dahl, Na Cai, Arthur Ko, Markku Laakso, Päivi Pajukanta, Jonathan Flint, Noah Zaitlen
Published 2019-04-01

Simvastatin profoundly impairs energy metabolism in primary human muscle cells

by Selina Mäkinen, Neeta Datta, Yen H Nguyen, Petro Kyrylenko, Markku Laakso, Heikki A Koistinen
Published 2020-12-01

Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells

by Maykel López Rodríguez, Dorota Kaminska, Kati Lappalainen, Jussi Pihlajamäki, Minna U. Kaikkonen, Markku Laakso
Published 2017-07-01

Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells.

by Nagendra Yaluri, Shalem Modi, Maykel López Rodríguez, Alena Stančáková, Johanna Kuusisto, Tarja Kokkola, Markku Laakso
Published 2015-01-01

Markers of tissue-specific insulin resistance predict the worsening of hyperglycemia, incident type 2 diabetes and cardiovascular disease.

by Mária Fízel'ová, Henna Cederberg, Alena Stančáková, Raimo Jauhiainen, Jagadish Vangipurapu, Johanna Kuusisto, Markku Laakso
Published 2014-01-01

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

by Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Piia Simonen, Johanna Kuusisto, Markku Laakso, Tatu A. Miettinen
Published 2010-08-01

Novel biomarkers associated with incident heart failure in 10 106 Finnish men

by Raimo Jauhiainen, Matti Jauhiainen, Jagadish Vangipurapu, Teemu Kuulasmaa, Mika Ala‐Korpela, Markku Laakso, Johanna Kuusisto
Published 2021-02-01

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

by Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Jyrki Ågren, Markku Laakso, Radhakrishnan A. Rajaratnam, Rainer Rauramaa, Tatu A. Miettinen
Published 2004-09-01

Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease

by Šárka Lehtonen, Ida Höytyläinen, Jenni Voutilainen, Tuuli-Maria Sonninen, Johanna Kuusisto, Markku Laakso, Riikka H. Hämäläinen, Minna Oksanen, Jari Koistinaho
Published 2018-07-01

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

by Markku Laakso, Johanna Kuusisto, Alena Stančáková, Teemu Kuulasmaa, Päivi Pajukanta, Aldons J. Lusis, Francis S. Collins, Karen L. Mohlke, Michael Boehnke
Published 2017-03-01

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

by Apolline Gallois, Joel Mefford, Arthur Ko, Amaury Vaysse, Hanna Julienne, Mika Ala-Korpela, Markku Laakso, Noah Zaitlen, Päivi Pajukanta, Hugues Aschard
Published 2019-10-01

Long-Term Effects of Placental Growth on Overweight and Body Composition

by Johan G. Eriksson, Jill Gelow, Kent L. Thornburg, Clive Osmond, Markku Laakso, Matti Uusitupa, Virpi Lindi, Eero Kajantie, David J. P. Barker
Published 2012-01-01

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.

by Benedicte Jørgenrud, Mikko Jalanko, Tiina Heliö, Pertti Jääskeläinen, Mika Laine, Mika Hilvo, Markku S Nieminen, Markku Laakso, Tuulia Hyötyläinen, Matej Orešič, Johanna Kuusisto
Published 2015-01-01