Prophylactic drug management for febrile seizures in children

by Martin Offringa, Richard Newton

Children are not just small adults: the urgent need for high-quality trial evidence in children.

by Terry P Klassen, Lisa Hartling, Jonathan C Craig, Martin Offringa
Published 2008-08-01

Outcome reporting recommendations for clinical trial protocols and reports: a scoping review

by Nancy J. Butcher, Emma J. Mew, Andrea Monsour, An-Wen Chan, David Moher, Martin Offringa
Published 2020-07-01

Publication Trends of Pediatric and Adult Randomized Controlled Trials in General Medical Journals, 2005–2018: A Citation Analysis

by Michael L. Groff, Martin Offringa, Abby Emdin, Quenby Mahood, Patricia C. Parkin, Eyal Cohen
Published 2020-12-01

Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes

by Anna Heath, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Terry P. Klassen, Naveen Poonai, Eleanor Pullenayegum
Published 2020-06-01

Innovative approaches to investigator-initiated, multicentre paediatric clinical trials in Canada

by Martin Offringa, Samina Ali, Naveen Poonai, Lisa Knisley, Serena Hickes, Geert W ’t Jong, Petros Pechlivanoglou, Thierry Lacaze
Published 2019-06-01

Outcome reporting in neonates experiencing withdrawal following opioid exposure in pregnancy: a systematic review

by Flora Shan, Sonya MacVicar, Karel Allegaert, Martin Offringa, Lauren M. Jansson, Sarah Simpson, Wendy Moulsdale, Lauren E. Kelly
Published 2020-03-01

Enzyme replacement therapy in perinatal hypophosphatasia: Case report of a negative outcome and lessons for clinical practice

by Gregory Costain, Aideen M. Moore, Lauren Munroe, Alison Williams, Randi Zlotnik Shaul, Cheryl Rockman-Greenberg, Martin Offringa, Peter Kannu
Published 2018-03-01

Patient and family engagement in the development of core outcome sets for two rare chronic diseases in children

by Shelley M. Vanderhout, Maureen Smith, Nicole Pallone, Kylie Tingley, Michael Pugliese, Pranesh Chakraborty, Sylvia Stockler, Martin Offringa, Nancy Butcher, Stuart G. Nicholls, Beth K. Potter
Published 2021-09-01

The intranasal dexmedetomidine plus ketamine for procedural sedation in children, adaptive randomized controlled non-inferiority multicenter trial (Ketodex): a statistical analysis...

by Anna Heath, Juan David Rios, Eleanor Pullenayegum, Petros Pechlivanoglou, Martin Offringa, Maryna Yaskina, Rick Watts, Shana Rimmer, Terry P. Klassen, Kamary Coriolano, Naveen Poonai, on behalf of the PERC-KIDSCAN Ketodex Study Group
Published 2021-01-01

Primary outcome reporting in adolescent depression clinical trials needs standardization

by Andrea Monsour, Emma J. Mew, Sagar Patel, Alyssandra Chee-a-tow, Leena Saeed, Lucia Santos, Darren B. Courtney, Priya N. Watson, Suneeta Monga, Peter Szatmari, Martin Offringa, Nancy J. Butcher
Published 2020-05-01

Non-steroidal or opioid analgesia use for children with musculoskeletal injuries (the No OUCH study): statistical analysis plan

by Anna Heath, Maryna Yaskina, Gareth Hopkin, Terry P. Klassen, Christopher McCabe, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Naveen Poonai, Samina Ali, on behalf of the KidsCAN PERC Innovative Pediatric Clinical Trials No OUCH Study Group
Published 2020-09-01

Comparative effectiveness of prophylactic therapies for necrotizing enterocolitis in preterm infants: Protocol for a network meta-analysis of randomized trials

by Behnam Sadeghirad, Ivan D Florez, Yaping Chang, Farid Forutan, Dena Zeraatkar, Rebecca L Morgan, Shaneela Shahid, Malgorzata M Bala, Joseph Beyene, Martin Offringa, Thomasin Adams-Webber, Philip M Sherman, Enas El-Gouhary, Gordon H Guyatt, Bradley C Johnston
Published 2018-01-01

A pragmatic randomized controlled trial of multi-dose oral ondansetron for pediatric gastroenteritis (the DOSE-AGE study): statistical analysis plan

by Anna Heath, Juan David Rios, Sarah Williamson-Urquhart, Petros Pechlivanoglou, Martin Offringa, Christopher McCabe, Gareth Hopkin, Amy C. Plint, Andrew Dixon, Darcy Beer, Serge Gouin, Gary Joubert, Terry P. Klassen, Stephen B. Freedman, on behalf of the PERC-KIDSCAN DOSE-AGE Study Group
Published 2020-08-01

Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT)

by Nancy J. Butcher, Andrea Monsour, Emma J. Mew, Peter Szatmari, Agostino Pierro, Lauren E. Kelly, Mufiza Farid-Kapadia, Alyssandra Chee-a-tow, Leena Saeed, Suneeta Monga, Wendy Ungar, Caroline B. Terwee, Sunita Vohra, Dean Fergusson, Lisa M. Askie, Paula R. Williamson, An-Wen Chan, David Moher, Martin Offringa
Published 2019-03-01

Establishing core outcome sets for phenylketonuria (PKU) and medium-chain Acyl-CoA dehydrogenase (MCAD) deficiency in children: study protocol for systematic reviews and Delphi sur...

by Beth K. Potter, Brian Hutton, Tammy J. Clifford, Nicole Pallone, Maureen Smith, Sylvia Stockler, Pranesh Chakraborty, Pauline Barbeau, Chantelle M. Garritty, Michael Pugliese, Alvi Rahman, Becky Skidmore, Laure Tessier, Kylie Tingley, Doug Coyle, Cheryl R. Greenberg, Lawrence Korngut, Alex MacKenzie, John J. Mitchell, Stuart Nicholls, Martin Offringa, Andreas Schulze, Monica Taljaard, In collaboration with the Canadian Inherited Metabolic Diseases Research Network
Published 2017-12-01

Outcomes in pediatric studies of medium-chain acyl-coA dehydrogenase (MCAD) deficiency and phenylketonuria (PKU): a review

by Michael Pugliese, Kylie Tingley, Andrea Chow, Nicole Pallone, Maureen Smith, Alvi Rahman, Pranesh Chakraborty, Michael T. Geraghty, Julie Irwin, Laure Tessier, Stuart G. Nicholls, Martin Offringa, Nancy J. Butcher, Ryan Iverson, Tammy J. Clifford, Sylvia Stockler, Brian Hutton, Karen Paik, Jessica Tao, Becky Skidmore, Doug Coyle, Kathleen Duddy, Sarah Dyack, Cheryl R. Greenberg, Shailly Jain Ghai, Natalya Karp, Lawrence Korngut, Jonathan Kronick, Alex MacKenzie, Jennifer MacKenzie, Bruno Maranda, John J. Mitchell, Murray Potter, Chitra Prasad, Andreas Schulze, Rebecca Sparkes, Monica Taljaard, Yannis Trakadis, Jagdeep Walia, Beth K. Potter, Canadian Inherited Metabolic Diseases Research Network
Published 2020-01-01

The bilirubin albumin ratio in the management of hyperbilirubinemia in preterm infants to improve neurodevelopmental outcome: a randomized controlled trial--BARTrial.

by Christian V Hulzebos, Peter H Dijk, Deirdre E van Imhoff, Arend F Bos, Enrico Lopriore, Martin Offringa, Selma A J Ruiter, Koen N J A van Braeckel, Paul F M Krabbe, Elise H Quik, Letty van Toledo-Eppinga, Debbie H G M Nuytemans, Aleid G van Wassenaer-Leemhuis, Manon J N Benders, Karen K M Korbeeck-van Hof, Richard A van Lingen, Liesbeth J M Groot Jebbink, Djien Liem, Petri Mansvelt, Jan Buijs, Paul Govaert, Ineke van Vliet, Twan L M Mulder, Cecile Wolfs, Willem P F Fetter, Celeste Laarman, BARTrial Study Group
Published 2014-01-01