Delivery of IL-35 by Lactococcus lactis Ameliorates Collagen-Induced Arthritis in Mice

by Massimo Maddaloni, Irina Kochetkova, Carol Hoffman, David W. Pascual
Published 2018-11-01

IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE).

by Agnieszka Rynda, Massimo Maddaloni, Javier Ochoa-Repáraz, Gayle Callis, David W Pascual
Published 2010-01-01

Milk-based nutraceutical for treating autoimmune arthritis via the stimulation of IL-10- and TGF-β-producing CD39+ regulatory T cells.

by Massimo Maddaloni, Irina Kochetkova, SangMu Jun, Gayle Callis, Theresa Thornburg, David W Pascual
Published 2015-01-01

Loss of sialic acid binding domain redirects protein σ1 to enhance M cell-directed vaccination.

by Dagmara Zlotkowska, Massimo Maddaloni, Carol Riccardi, Nancy Walters, Kathryn Holderness, Gayle Callis, Agnieszka Rynda-Apple, David W Pascual
Published 2012-01-01

Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.

by Herman F Staats, Jeffrey R Fielhauer, Afton L Thompson, Alice A Tripp, Ashley E Sobel, Massimo Maddaloni, Soman N Abraham, David W Pascual
Published 2011-01-01

Stimulation of regulatory T cells with Lactococcus lactis expressing enterotoxigenic E. coli colonization factor antigen 1 retains salivary flow in a genetic model of Sjögren’s syn...

by Ali Akgul, Massimo Maddaloni, Sang Mu Jun, Andrew S. Nelson, Vanessa Aguilera Odreman, Carol Hoffman, Ella Bhagyaraj, Alexandria Voigt, Jeffrey R. Abbott, Cuong Q. Nguyen, David W. Pascual
Published 2021-04-01