Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus.

by Hongshuo Song, Bhavna Hora, Tanmoy Bhattacharya, Nilu Goonetilleke, Michael K P Liu, Kevin Wiehe, Hui Li, Shilpa S Iyer, Andrew J McMichael, Alan S Perelson, Feng Gao
Published 2014-01-01

A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies

by Donglai Liu, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, Guido Ferrari, Andrew J. McMichael, Tanmoy Bhattacharya, Alan S. Perelson, Feng Gao
Published 2017-10-01

Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection.

by Holger B Kramer, Kerry J Lavender, Li Qin, Andrea R Stacey, Michael K P Liu, Katalin di Gleria, Alison Simmons, Nancy Gasper-Smith, Barton F Haynes, Andrew J McMichael, Persephone Borrow, Benedikt M Kessler
Published 2010-05-01

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.

by Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K P Liu, Emma L Turnbull, Jesus F Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D Tomaras, Barton F Haynes, Clive M Gray, Persephone Borrow, Mario Roederer, Andrew J McMichael, Kent J Weinhold
Published 2011-02-01