Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences

by Dhanushika Ratnayake, Morgan Newman, Michael Lardelli
Published 2018-03-01

The zebrafish orthologue of familial Alzheimer's disease gene PRESENILIN 2 is required for normal adult melanotic skin pigmentation.

by Haowei Jiang, Morgan Newman, Michael Lardelli
Published 2018-01-01

Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production

by Morgan Newman, Nhi Hin, Stephen Pederson, Michael Lardelli
Published 2019-05-01

Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease.

by Morgan Newman, Lena Halter, Anne Lim, Michael Lardelli
Published 2017-01-01

No observed effect on brain vasculature of Alzheimer’s disease-related mutations in the zebrafish presenilin 1 gene

by Karissa Barthelson, Morgan Newman, Cameron J. Nowell, Michael Lardelli
Published 2021-01-01

Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s dis...

by Karissa Barthelson, Stephen Martin Pederson, Morgan Newman, Michael Lardelli
Published 2020-10-01

Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2.

by Haowei Jiang, Stephen Martin Pederson, Morgan Newman, Yang Dong, Karissa Barthelson, Michael Lardelli
Published 2020-01-01

Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer’s disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM fun...

by Yang Dong, Morgan Newman, Stephen M. Pederson, Karissa Barthelson, Nhi Hin, Michael Lardelli
Published 2021-03-01

Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer’s Disease

by Amanda L. Lumsden, Amanda L. Lumsden, Jack T. Rogers, Shohreh Majd, Morgan Newman, Greg T. Sutherland, Giuseppe Verdile, Michael Lardelli
Published 2018-08-01

Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome

by Karissa Barthelson, Lachlan Baer, Yang Dong, Melanie Hand, Zac Pujic, Morgan Newman, Geoffrey J. Goodhill, Geoffrey J. Goodhill, Robert I. Richards, Stephen M. Pederson, Michael Lardelli
Published 2021-05-01

The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes.

by Mathew J Sharman, Seyyed H Moussavi Nik, Mengqi M Chen, Daniel Ong, Linda Wijaya, Simon M Laws, Kevin Taddei, Morgan Newman, Michael Lardelli, Ralph N Martins, Giuseppe Verdile
Published 2013-01-01

Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2.

by Nhi Hin, Morgan Newman, Jan Kaslin, Alon M Douek, Amanda Lumsden, Seyed Hani Moussavi Nik, Yang Dong, Xin-Fu Zhou, Noralyn B Mañucat-Tan, Alastair Ludington, David L Adelson, Stephen Pederson, Michael Lardelli
Published 2020-01-01