Recent advances in understanding inhibitor of apoptosis proteins [version 1; referees: 2 approved]

by Najoua Lalaoui, David Lawrence Vaux
Published 2018-12-01

TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT.

by Najoua Lalaoui, Aymeric Morlé, Delphine Mérino, Guillaume Jacquemin, Elisabetta Iessi, Alexandre Morizot, Sarah Shirley, Bruno Robert, Eric Solary, Carmen Garrido, Olivier Micheau
Published 2011-01-01

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

by Diane Moujalled, Pradnya Gangatirkar, Maria Kauppi, Jason Corbin, Marion Lebois, James M. Murphy, Najoua Lalaoui, Joanne M. Hildebrand, John Silke, Warren S. Alexander, Emma C. Josefsson
Published 2021-01-01

Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.

by Elisabetta Iessi, Luciana Zischler, Aurélie Etringer, Marion Bergeret, Aymeric Morlé, Guillaume Jacquemin, Alexandre Morizot, Sarah Shirley, Najoua Lalaoui, Selene L Elifio-Esposito, Stefano Fais, Carmen Garrido, Eric Solary, Olivier Micheau
Published 2015-01-01

MK2 Inhibition Induces p53-Dependent Senescence in Glioblastoma Cells

by Athena F. Phoa, Ariadna Recasens, Fadi M. S. Gurgis, Tara A. Betts, Sharleen V. Menezes, Diep Chau, Kristiina Nordfors, Joonas Haapasalo, Hannu Haapasalo, Terrance G. Johns, Brett W. Stringer, Bryan W. Day, Michael E. Buckland, Najoua Lalaoui, Lenka Munoz
Published 2020-03-01

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

by Charis E. Teh, Najoua Lalaoui, Reema Jain, Antonia N. Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M. Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A. O’Reilly, Dale I. Godfrey, Gordon K. Smyth, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, Daniel H. D. Gray
Published 2016-11-01

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

by Emma J. Petrie, Jarrod J. Sandow, Wil I.L. Lehmann, Lung-Yu Liang, Diane Coursier, Samuel N. Young, Wilhelmus J.A. Kersten, Cheree Fitzgibbon, André L. Samson, Annette V. Jacobsen, Kym N. Lowes, Amanda E. Au, Hélène Jousset Sabroux, Najoua Lalaoui, Andrew I. Webb, Guillaume Lessene, Gerard Manning, Isabelle S. Lucet, James M. Murphy
Published 2019-09-01

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

by Ajithkumar Vasanthakumar, Yang Liao, Peggy Teh, Maria F. Pascutti, Anna E. Oja, Alexandra L. Garnham, Renee Gloury, Jessica C. Tempany, Tom Sidwell, Eloy Cuadrado, Paul Tuijnenburg, Taco W. Kuijpers, Najoua Lalaoui, Lisa A. Mielke, Vanessa L. Bryant, Philip D. Hodgkin, John Silke, Gordon K. Smyth, Martijn A. Nolte, Wei Shi, Axel Kallies
Published 2017-09-01

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice

by James A Rickard, Holly Anderton, Nima Etemadi, Ueli Nachbur, Maurice Darding, Nieves Peltzer, Najoua Lalaoui, Kate E Lawlor, Hannah Vanyai, Cathrine Hall, Aleks Bankovacki, Lahiru Gangoda, Wendy Wei-Lynn Wong, Jason Corbin, Chunzi Huang, Edward S Mocarski, James M Murphy, Warren S Alexander, Anne K Voss, David L Vaux, William J Kaiser, Henning Walczak, John Silke
Published 2014-12-01

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

by Andre L. Samson, Ying Zhang, Niall D. Geoghegan, Xavier J. Gavin, Katherine A. Davies, Michael J. Mlodzianoski, Lachlan W. Whitehead, Daniel Frank, Sarah E. Garnish, Cheree Fitzgibbon, Anne Hempel, Samuel N. Young, Annette V. Jacobsen, Wayne Cawthorne, Emma J. Petrie, Maree C. Faux, Kristy Shield-Artin, Najoua Lalaoui, Joanne M. Hildebrand, John Silke, Kelly L. Rogers, Guillaume Lessene, Edwin D. Hawkins, James M. Murphy
Published 2020-06-01