Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies

by Alessandra Zarantonello, Henrik Pedersen, Nick S Laursen, Gregers R Andersen
Published 2021-02-01

Isolation and Characterization of Nanobodies against a Zinc-Transporting P-Type ATPase

by Elena Longhin, Christina Grønberg, Qiaoxia Hu, Annette Susanne Duelli, Kasper Røjkjær Andersen, Nick Stub Laursen, Pontus Gourdon
Published 2018-11-01

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System

by Nick S. Laursen, Dennis V. Pedersen, Heidi Gytz, Alessandra Zarantonello, Jens Magnus Bernth Jensen, Annette G. Hansen, Steffen Thiel, Gregers R. Andersen
Published 2020-07-01

Structural signatures in EPR3 define a unique class of plant carbohydrate receptors

by Jaslyn E. M. M. Wong, Kira Gysel, Thea G. Birkefeldt, Maria Vinther, Artur Muszyński, Parastoo Azadi, Nick S. Laursen, John T. Sullivan, Clive W. Ronson, Jens Stougaard, Kasper R. Andersen
Published 2020-07-01

Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction

by Frederic Jabs, Melanie Plum, Nick S. Laursen, Rasmus K. Jensen, Brian Mølgaard, Michaela Miehe, Marco Mandolesi, Michèle M. Rauber, Wolfgang Pfützner, Thilo Jakob, Christian Möbs, Gregers R. Andersen, Edzard Spillner
Published 2018-01-01

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

by Dennis V. Pedersen, Trine A. F. Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram, Rasmus K. Jensen, Sofia M. M. Mazarakis, Margot Revel, Carine El Sissy, Steen V. Petersen, Kresten Lindorff-Larsen, Steffen Thiel, Nick S. Laursen, Véronique Fremeaux-Bacchi, Gregers R. Andersen
Published 2019-08-01