Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.

by V Chandana Epa, Olan Dolezal, Larissa Doughty, Xiaowen Xiao, Christian Jost, Andreas Plückthun, Timothy E Adams
Published 2013-01-01

Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK.

by Sandeep Chhabra, Nicholas Barlow, Olan Dolezal, Meghan K Hattarki, Janet Newman, Thomas S Peat, Bim Graham, James D Swarbrick
Published 2013-01-01

A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6.

by Remy Robert, Laurent Juglair, Ee X Lim, Caroline Ang, Carl J H Wang, Gregor Ebert, Olan Dolezal, Charles R Mackay
Published 2017-01-01

Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor.

by Sandeep Chhabra, Olan Dolezal, Brett M Collins, Janet Newman, Jamie S Simpson, Ian G Macreadie, Ross Fernley, Thomas S Peat, James D Swarbrick
Published 2012-01-01

Kinetic Characterization of a Panel of High-Affinity Monoclonal Antibodies Targeting Ricin and Recombinant Re-Formatting for Biosensor Applications

by Michelle Cummins, Con Dogovski, Remy Robert, Malcolm Alderton, Damien Chong, David Proll, Luisa Pontes-Braz, Anna Raicevic, Meghan Hattarki, Stewart Nuttall, Olan Dolezal
Published 2014-05-01

Shark Variable New Antigen Receptor (VNAR) Single Domain Antibody Fragments: Stability and Diagnostic Applications

by Stewart Nuttall, Matthew A. Perugini, Iveth González, Joanne L. Casey, Abdulmonem Sanalla, Miles Barraclough, Con Dogovski, Julie Angerosa, Kathy Parisi, Olan Dolezal, Katherine Griffiths, Michael Foley
Published 2013-01-01

Fragment screening for a protein-protein interaction inhibitor to WDR5

by Matthew L. Dennis, Benjamin J. Morrow, Olan Dolezal, Anthony N. Cuzzupe, Alexandra E. Stupple, Janet Newman, John Bentley, Meghan Hattarki, Stewart D. Nuttall, Richard C. Foitzik, Ian P. Street, Paul A. Stupple, Brendon J. Monahan, Thomas. S. Peat
Published 2019-11-01

Correction: Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

by Thomas S. Peat, David I. Rhodes, Nick Vandegraaff, Giang Le, Jessica A. Smith, Lisa J. Clark, Eric D. Jones, Jonathan A. V. Coates, Neeranat Thienthong, Janet Newman, Olan Dolezal, Roger Mulder, John H. Ryan, G. Paul Savage, Craig L. Francis, John J. Deadman
Published 2013-01-01

Correction: Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.

by Thomas S. Peat, David I. Rhodes, Nick Vandegraaff, Giang Le, Jessica A. Smith, Lisa J. Clark, Eric D. Jones, Jonathan A. V. Coates, Neeranat Thienthong, Janet Newman, Olan Dolezal, Roger Mulder, John H. Ryan, G. Paul Savage, Craig L. Francis, John J. Deadman
Published 2013-01-01

Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design.

by Thomas S Peat, David I Rhodes, Nick Vandegraaff, Giang Le, Jessica A Smith, Lisa J Clark, Eric D Jones, Jonathan A V Coates, Neeranat Thienthong, Janet Newman, Olan Dolezal, Roger Mulder, John H Ryan, G Paul Savage, Craig L Francis, John J Deadman
Published 2012-01-01