Depletion of Luminal Pyridine Nucleotides in the Endoplasmic Reticulum Activates Autophagy with the Involvement of mTOR Pathway

by Orsolya Kapuy, Gábor Bánhegyi
Published 2013-01-01

GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy.

by Marianna Holczer, Gábor Bánhegyi, Orsolya Kapuy
Published 2016-01-01

mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study

by Orsolya Kapuy, P.K. Vinod, Gábor Bánhegyi
Published 2014-01-01

Therapeutic Approach of KRAS Mutant Tumours by the Combination of Pharmacologic Ascorbate and Chloroquine

by Orsolya Kapuy, Kinga Makk-Merczel, András Szarka
Published 2021-04-01

Autophagy-dependent survival is controlled with a unique regulatory network upon various cellular stress events

by Orsolya Kapuy, Marianna Holczer, Margita Márton, Tamás Korcsmáros
Published 2021-03-01

NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.

by Margita Márton, Nikolett Tihanyi, Pál Gyulavári, Gábor Bánhegyi, Orsolya Kapuy
Published 2018-01-01

A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

by Marianna Holczer, Margita Márton, Anita Kurucz, Gábor Bánhegyi, Orsolya Kapuy
Published 2015-01-01

Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response

by Orsolya Kapuy, Diána Papp, Tibor Vellai, Gábor Bánhegyi, Tamás Korcsmáros
Published 2018-03-01

A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress

by Marianna Holczer, Bence Hajdú, Tamás Lőrincz, András Szarka, Gábor Bánhegyi, Orsolya Kapuy
Published 2019-11-01

Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress

by Marianna Holczer, Boglárka Besze, Veronika Zámbó, Miklós Csala, Gábor Bánhegyi, Orsolya Kapuy
Published 2018-01-01

A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway

by Margita Márton, Anita Kurucz, Beáta Lizák, Éva Margittai, Gábor Bánhegyi, Orsolya Kapuy
Published 2017-01-01