Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers

by Pranavi Garlapati, Jinjie Ling, Paul J. Chiao, Jie Fu
Published 2021-06-01

Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.

by Alakesh Bera, Shujie Zhao, Lin Cao, Paul J Chiao, James W Freeman
Published 2013-01-01

Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling

by Christophe Glorieux, Xiaojun Xia, Yong-Qiao He, Yumin Hu, Kelly Cremer, Annie Robert, Junchen Liu, Fen Wang, Jianhua Ling, Paul J. Chiao, Peng Huang
Published 2021-01-01

Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis.

by Zhe Chang, Huaiqiang Ju, Jianhua Ling, Zhuonan Zhuang, Zhongkui Li, Huamin Wang, Jason B Fleming, James W Freeman, Dihua Yu, Peng Huang, Paul J Chiao
Published 2014-01-01

SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium.

by Ya'an Kang, Jianhua Ling, Rei Suzuki, David Roife, Xavier Chopin-Laly, Mark J Truty, Deyali Chatterjee, Huamin Wang, Ryan M Thomas, Matthew H Katz, Paul J Chiao, Jason B Fleming
Published 2014-01-01

Induction of Apoptosis in Tumor-Associated Endothelial Cells and Therapy of Orthotopic Human Pancreatic Carcinoma in Nude Mice

by Kenji Yokoi, Sun-Jin Kim, Premal Thaker, Sertac Yazici, Do-Hyun Nam, Junqin He, Takamitsu Sasaki, Paul J. Chiao, Guido M. Sclabas, James L. Abbruzzese, Stanley R. Hamilton, Isaiah J. Fidler
Published 2005-07-01

Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma

by Huai-Qiang Ju, Haoqiang Ying, Tian Tian, Jianhua Ling, Jie Fu, Yu Lu, Min Wu, Lifeng Yang, Abhinav Achreja, Gang Chen, Zhuonan Zhuang, Huamin Wang, Deepak Nagrath, Jun Yao, Mien-Chie Hung, Ronald A. DePinho, Peng Huang, Rui-Hua Xu, Paul J. Chiao
Published 2017-02-01