Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes

by Amir Ariff, Amir Ariff, Phillip E. Melton, Phillip E. Melton, Shaun P. Brennecke, Shaun P. Brennecke, Eric K. Moses, Eric K. Moses, Eric K. Moses
Published 2019-03-01

Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes

by Stephanie Bridgeman, Wendy Northrop, Gaewyn Ellison, Thiru Sabapathy, Phillip E. Melton, Philip Newsholme, Cyril D. S. Mamotte
Published 2019-04-01

Epigenetics, heritability and longitudinal analysis

by Haakon E. Nustad, Marcio Almeida, Angelo J. Canty, Marissa LeBlanc, Christian M. Page, Phillip E. Melton
Published 2018-09-01

Genome-wide association study of autistic-like traits in a general population study of young adults

by Rachel Maree Jones, Gemma eCadby, Phillip eMelton, Lawrence eAbraham, Andrew eWhitehouse, Eric eMoses
Published 2013-10-01

Maternal Smoking During Pregnancy Induces Persistent Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

by Sebastian Rauschert, Phillip E. Melton, Phillip E. Melton, Graham Burdge, Jeffrey M. Craig, Jeffrey M. Craig, Keith M. Godfrey, Keith M. Godfrey, Joanna D. Holbrook, Karen Lillycrop, Trevor A. Mori, Lawrence J. Beilin, Wendy H. Oddy, Craig Pennell, Rae-Chi Huang
Published 2019-09-01

In Epigenomic Studies, Including Cell-Type Adjustments in Regression Models Can Introduce Multicollinearity, Resulting in Apparent Reversal of Direction of Association

by Sheila J. Barton, Sheila J. Barton, Phillip E. Melton, Phillip E. Melton, Philip Titcombe, Philip Titcombe, Robert Murray, Sebastian Rauschert, Karen A. Lillycrop, Karen A. Lillycrop, Rae-Chi Huang, Joanna D. Holbrook, Keith M. Godfrey, Keith M. Godfrey, Keith M. Godfrey
Published 2019-09-01

Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury.

by Wissam Chiha, Chrisna J LeVaillant, Carole A Bartlett, Alex W Hewitt, Phillip E Melton, Melinda Fitzgerald, Alan R Harvey
Published 2018-01-01

Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes.

by Hannah E J Yong, Phillip E Melton, Matthew P Johnson, Katy A Freed, Bill Kalionis, Padma Murthi, Shaun P Brennecke, Rosemary J Keogh, Eric K Moses
Published 2015-01-01

Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts

by Rachel M. Jones, Phillip E. Melton, Mark Pinese, Alexander J. Rea, Evan Ingley, Mandy L. Ballinger, International Sarcoma Kindred Study, David J. Wood, David M. Thomas, Eric K. Moses
Published 2019-05-01

Western oropharyngeal and gut microbial profiles are associated with allergic conditions in Chinese immigrant children

by Jing Guo, Quanjun Lv, Amir Ariff, Xiaoping Zhang, Christopher S. Peacock, Yong Song, Xiajie Wen, Aarti Saiganesh, Phillip E. Melton, Gary A. Dykes, Eric K. Moses, Peter N. LE Souëf, Fengmin Lu, Guicheng Zhang
Published 2019-08-01

Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study[S]

by Gemma Cadby, Phillip E. Melton, Nina S. McCarthy, Corey Giles, Natalie A. Mellett, Kevin Huynh, Joseph Hung, John Beilby, Marie-Pierre Dubé, Gerald F. Watts, John Blangero, Peter J. Meikle, Eric K. Moses
Published 2020-04-01

Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars

by Mansour A. Alghamdi, Hilary J. Wallace, Phillip E. Melton, Eric K. Moses, Andrew Stevenson, Laith N. AL-Eitan, Suzanne Rea, Janine M. Duke, Patricia L. Danielsen, Cecilia M. Prêle, Fiona M. Wood, Mark W. Fear
Published 2020-06-01

A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

by Rohina Rubicz, Robert Yolken, Eugene Drigalenko, Melanie A Carless, Thomas D Dyer, Lara Bauman, Phillip E Melton, Jack W Kent, John B Harley, Joanne E Curran, Matthew P Johnson, Shelley A Cole, Laura Almasy, Eric K Moses, Nikhil V Dhurandhar, Ellen Kraig, John Blangero, Charles T Leach, Harald H H Göring
Published 2013-01-01

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adultsResearch in context

by Priyanka Parmar, Estelle Lowry, Giovanni Cugliari, Matthew Suderman, Rory Wilson, Ville Karhunen, Toby Andrew, Petri Wiklund, Matthias Wielscher, Simonetta Guarrera, Alexander Teumer, Benjamin Lehne, Lili Milani, Niek de Klein, Pashupati P. Mishra, Phillip E. Melton, Pooja R. Mandaviya, Silva Kasela, Jana Nano, Weihua Zhang, Yan Zhang, Andre G. Uitterlinden, Annette Peters, Ben Schöttker, Christian Gieger, Denise Anderson, Dorret I. Boomsma, Hans J. Grabe, Salvatore Panico, Jan H. Veldink, Joyce B.J. van Meurs, Leonard van den Berg, Lawrence J. Beilin, Lude Franke, Marie Loh, Marleen M.J. van Greevenbroek, Matthias Nauck, Mika Kähönen, Mikko A. Hurme, Olli T. Raitakari, Oscar H. Franco, P.Eline Slagboom, Pim van der Harst, Sonja Kunze, Stephan B. Felix, Tao Zhang, Wei Chen, Trevor A. Mori, Amelie Bonnefond, Bastiaan T. Heijmans, Taulant Muka, Jaspal S. Kooner, Krista Fischer, Melanie Waldenberger, Philippe Froguel, Rae-Chi Huang, Terho Lehtimäki, Wolfgang Rathmann, Caroline L. Relton, Giuseppe Matullo, Hermann Brenner, Niek Verweij, Shengxu Li, John C. Chambers, Marjo-Riitta Järvelin, Sylvain Sebert
Published 2018-12-01

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

by Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers, Alvin T. Kho, Ritu Roy, Lu Gao, Isabella Annesi-Maesano, Pooja Jain, Michelle Plusquin, Manolis Kogevinas, Catherine Allard, Florianne O. Vehmeijer, Nabila Kazmi, Lucas A. Salas, Faisal I. Rezwan, Hongmei Zhang, Sylvain Sebert, Darina Czamara, Sheryl L. Rifas-Shiman, Phillip E. Melton, Debbie A. Lawlor, Göran Pershagen, Carrie V. Breton, Karen Huen, Nour Baiz, Luigi Gagliardi, Tim S. Nawrot, Eva Corpeleijn, Patrice Perron, Liesbeth Duijts, Ellen Aagaard Nohr, Mariona Bustamante, Susan L. Ewart, Wilfried Karmaus, Shanshan Zhao, Christian M. Page, Zdenko Herceg, Marjo-Riitta Jarvelin, Jari Lahti, Andrea A. Baccarelli, Denise Anderson, Priyadarshini Kachroo, Caroline L. Relton, Anna Bergström, Brenda Eskenazi, Munawar Hussain Soomro, Paolo Vineis, Harold Snieder, Luigi Bouchard, Vincent W. Jaddoe, Thorkild I. A. Sørensen, Martine Vrijheid, S. Hasan Arshad, John W. Holloway, Siri E. Håberg, Per Magnus, Terence Dwyer, Elisabeth B. Binder, Dawn L. DeMeo, Judith M. Vonk, John Newnham, Kelan G. Tantisira, Inger Kull, Joseph L. Wiemels, Barbara Heude, Jordi Sunyer, Wenche Nystad, Monica C. Munthe-Kaas, Katri Räikkönen, Emily Oken, Rae-Chi Huang, Scott T. Weiss, Josep Maria Antó, Jean Bousquet, Ashish Kumar, Cilla Söderhäll, Catarina Almqvist, Andres Cardenas, Olena Gruzieva, Cheng-Jian Xu, Sarah E. Reese, Juha Kere, Petter Brodin, Olivia Solomon, Matthias Wielscher, Nina Holland, Akram Ghantous, Marie-France Hivert, Janine F. Felix, Gerard H. Koppelman, Stephanie J. London, Erik Melén
Published 2020-03-01

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

by Leanne K. Küpers, Claire Monnereau, Gemma C. Sharp, Paul Yousefi, Lucas A. Salas, Akram Ghantous, Christian M. Page, Sarah E. Reese, Allen J. Wilcox, Darina Czamara, Anne P. Starling, Alexei Novoloaca, Samantha Lent, Ritu Roy, Cathrine Hoyo, Carrie V. Breton, Catherine Allard, Allan C. Just, Kelly M. Bakulski, John W. Holloway, Todd M. Everson, Cheng-Jian Xu, Rae-Chi Huang, Diana A. van der Plaat, Matthias Wielscher, Simon Kebede Merid, Vilhelmina Ullemar, Faisal I. Rezwan, Jari Lahti, Jenny van Dongen, Sabine A. S. Langie, Tom G. Richardson, Maria C. Magnus, Ellen A. Nohr, Zongli Xu, Liesbeth Duijts, Shanshan Zhao, Weiming Zhang, Michelle Plusquin, Dawn L. DeMeo, Olivia Solomon, Joosje H. Heimovaara, Dereje D. Jima, Lu Gao, Mariona Bustamante, Patrice Perron, Robert O. Wright, Irva Hertz-Picciotto, Hongmei Zhang, Margaret R. Karagas, Ulrike Gehring, Carmen J. Marsit, Lawrence J. Beilin, Judith M. Vonk, Marjo-Riitta Jarvelin, Anna Bergström, Anne K. Örtqvist, Susan Ewart, Pia M. Villa, Sophie E. Moore, Gonneke Willemsen, Arnout R. L. Standaert, Siri E. Håberg, Thorkild I. A. Sørensen, Jack A. Taylor, Katri Räikkönen, Ivana V. Yang, Katerina Kechris, Tim S. Nawrot, Matt J. Silver, Yun Yun Gong, Lorenzo Richiardi, Manolis Kogevinas, Augusto A. Litonjua, Brenda Eskenazi, Karen Huen, Hamdi Mbarek, Rachel L. Maguire, Terence Dwyer, Martine Vrijheid, Luigi Bouchard, Andrea A. Baccarelli, Lisa A. Croen, Wilfried Karmaus, Denise Anderson, Maaike de Vries, Sylvain Sebert, Juha Kere, Robert Karlsson, Syed Hasan Arshad, Esa Hämäläinen, Michael N. Routledge, Dorret I. Boomsma, Andrew P. Feinberg, Craig J. Newschaffer, Eva Govarts, Matthieu Moisse, M. Daniele Fallin, Erik Melén, Andrew M. Prentice, Eero Kajantie, Catarina Almqvist, Emily Oken, Dana Dabelea, H. Marike Boezen, Phillip E. Melton, Rosalind J. Wright, Gerard H. Koppelman, Letizia Trevisi, Marie-France Hivert, Jordi Sunyer, Monica C. Munthe-Kaas, Susan K. Murphy, Eva Corpeleijn, Joseph Wiemels, Nina Holland, Zdenko Herceg, Elisabeth B. Binder, George Davey Smith, Vincent W. V. Jaddoe, Rolv T. Lie, Wenche Nystad, Stephanie J. London, Debbie A. Lawlor, Caroline L. Relton, Harold Snieder, Janine F. Felix
Published 2019-04-01