CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling

by Raul Torres-Ruiz, Sandra Rodriguez-Perales
Published 2015-09-01

CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges

by Marta Martinez-Lage, Pilar Puig-Serra, Pablo Menendez, Raul Torres-Ruiz, Sandra Rodriguez-Perales
Published 2018-11-01

The “Never-Ending” Mouse Models for MLL-Rearranged Acute Leukemia Are Still Teaching Us

by Katrin Ottersbach, Alejandra Sanjuan-Pla, Raúl Torres-Ruíz, Clara Bueno, Talia Velasco-Hernández, Pablo Menendez
Published 2018-08-01

Functional characterization of two enhancers located downstream FOXP2

by Raúl Torres-Ruiz, Antonio Benítez-Burraco, Marta Martínez-Lage, Sandra Rodríguez-Perales, Paloma García-Bellido
Published 2019-05-01

Detection of chromosome instability by interphase FISH in mouse and human tissues

by Raul Torres-Ruiz, Tatiana P. Grazioso, Marta Brandt, Marta Martinez-Lage, Sandra Rodriguez-Perales, Nabil Djouder
Published 2021-09-01

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

by Jennifer Redondo-Antón, MG Fontela, Laura Notario, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Elena Lorente, Pilar Lauzurica
Published 2020-10-01

Fast Diffusion Sustains Plasma Membrane Accumulation of Phosphatase of Regenerating Liver-1

by Patricia Castro-Sánchez, Sara Hernández-Pérez, Oscar Aguilar-Sopeña, Rocia Ramírez-Muñoz, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, Pedro Roda-Navarro
Published 2020-12-01

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

by Barbara Oldrini, Álvaro Curiel-García, Carolina Marques, Veronica Matia, Özge Uluçkan, Osvaldo Graña-Castro, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Jason T. Huse, Massimo Squatrito
Published 2018-04-01

RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment

by Alvaro Torres-Gomez, Jose Luis Sanchez-Trincado, Víctor Toribio, Raul Torres-Ruiz, Sandra Rodríguez-Perales, María Yáñez-Mó, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente
Published 2020-05-01

Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9

by Raul Torres-Ruiz, Marta Martinez-Lage, Maria C. Martin, Aida Garcia, Clara Bueno, Julio Castaño, Juan C. Ramirez, Pablo Menendez, Juan C. Cigudosa, Sandra Rodriguez-Perales
Published 2017-05-01

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

by Julio Castaño, Clara Bueno, Senda Jiménez-Delgado, Heleia Roca-Ho, Mario F. Fraga, Agustín F. Fernandez, Mahito Nakanishi, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Pablo Menéndez
Published 2017-05-01

Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome

by Antonio Benítez-Burraco, Montserrat Barcos-Martínez, Montserrat Barcos-Martínez, Isabel Espejo-Portero, Isabel Espejo-Portero, Maite Fernández-Urquiza, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Ma Salud Jiménez-Romero
Published 2018-06-01

Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

by Paolo Petazzi, Raul Torres-Ruiz, Antonella Fidanza, Heleia Roca-Ho, Francisco Gutierrez-Agüera, Julio Castaño, Sandra Rodriguez-Perales, Rafael Díaz de la Guardia, Belén López-Millán, Anna Bigas, Lesley M. Forrester, Clara Bueno, Pablo Menéndez
Published 2020-06-01

Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

by Juan Miguel Baquero, Carlos Benítez-Buelga, Varshni Rajagopal, Zhao Zhenjun, Raúl Torres-Ruiz, Sarah Müller, Bishoy M. F. Hanna, Olga Loseva, Olov Wallner, Maurice Michel, Sandra Rodríguez-Perales, Helge Gad, Torkild Visnes, Thomas Helleday, Javier Benítez, Ana Osorio
Published 2021-02-01

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency

by Alvaro Muñoz-López, Damià Romero-Moya, Cristina Prieto, Verónica Ramos-Mejía, Antonio Agraz-Doblas, Ignacio Varela, Marcus Buschbeck, Anna Palau, Xonia Carvajal-Vergara, Alessandra Giorgetti, Anthony Ford, Majlinda Lako, Isabel Granada, Neus Ruiz-Xivillé, Sandra Rodríguez-Perales, Raul Torres-Ruíz, Ronald W. Stam, Jose Luis Fuster, Mario F. Fraga, Mahito Nakanishi, Gianni Cazzaniga, Michela Bardini, Isabel Cobo, Gustavo F. Bayon, Agustin F. Fernandez, Clara Bueno, Pablo Menendez
Published 2016-10-01