Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity

by Joana B Pereira, Rik Ossenkoppele, Sebastian Palmqvist, Tor Olof Strandberg, Ruben Smith, Eric Westman, Oskar Hansson
Published 2019-12-01

Is intracranial volume a suitable proxy for brain reserve?

by Anna Catharina van Loenhoud, Colin Groot, Jacob William Vogel, Wiesje Maria van der Flier, Rik Ossenkoppele
Published 2018-09-01

Tau-related grey matter network breakdown across the Alzheimer’s disease continuum

by Wiesje Pelkmans, Rik Ossenkoppele, Ellen Dicks, Olof Strandberg, Frederik Barkhof, Betty M. Tijms, Joana B. Pereira, Oskar Hansson
Published 2021-08-01

Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer’s disease: a cohort study

by Niklas Mattsson, Rik Ossenkoppele, Ruben Smith, Olof Strandberg, Tomas Ohlsson, Jonas Jögi, Sebastian Palmqvist, Erik Stomrud, Oskar Hansson
Published 2018-08-01

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

by Nicolai Franzmeier, Julia Neitzel, Anna Rubinski, Ruben Smith, Olof Strandberg, Rik Ossenkoppele, Oskar Hansson, Michael Ewers, Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2020-01-01

[11C]PIB amyloid quantification: effect of reference region selection

by Fiona Heeman, Janine Hendriks, Isadora Lopes Alves, Rik Ossenkoppele, Nelleke Tolboom, Bart N. M. van Berckel, Adriaan A. Lammertsma, Maqsood Yaqub, on behalf of the AMYPAD Consortium
Published 2020-10-01

Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar?

by Carolyn A. Fredericks, Jesse A. Brown, Jersey Deng, Abigail Kramer, Rik Ossenkoppele, Katherine Rankin, Joel H. Kramer, Bruce L. Miller, Gil D. Rabinovici, William W. Seeley
Published 2019-01-01

Amyloid‐β PET and CSF in an autopsy‐confirmed cohort

by Juhan Reimand, Baayla D. C. Boon, Lyduine E. Collij, Charlotte E. Teunissen, Annemieke J. M. Rozemuller, Bart N. M. vanBerckel, Philip Scheltens, Rik Ossenkoppele, Femke Bouwman
Published 2020-11-01

Discordant amyloid-β PET and CSF biomarkers and its clinical consequences

by Arno de Wilde, Juhan Reimand, Charlotte E. Teunissen, Marissa Zwan, Albert D. Windhorst, Ronald Boellaard, Wiesje M. van der Flier, Philip Scheltens, Bart N. M. van Berckel, Femke Bouwman, Rik Ossenkoppele
Published 2019-09-01

Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer’s disease spectrum

by Tessa Timmers, Rik Ossenkoppele, Emma E. Wolters, Sander C. J. Verfaillie, Denise Visser, Sandeep S. V. Golla, Frederik Barkhof, Philip Scheltens, Ronald Boellaard, Wiesje M. van der Flier, Bart N. M. van Berckel
Published 2019-07-01

PET and CSF amyloid-β status are differently predicted by patient features: information from discordant cases

by Juhan Reimand, Arno de Wilde, Charlotte E. Teunissen, Marissa Zwan, Albert D. Windhorst, Ronald Boellaard, Frederik Barkhof, Wiesje M. van der Flier, Philip Scheltens, Bart N. M. van Berckel, Rik Ossenkoppele, Femke Bouwman
Published 2019-12-01

Widespread disruption of functional brain organization in early-onset Alzheimer's disease.

by Sofie M Adriaanse, Maja A A Binnewijzend, Rik Ossenkoppele, Betty M Tijms, Wiesje M van der Flier, Teddy Koene, Lieke L Smits, Alle Meije Wink, Philip Scheltens, Bart N M van Berckel, Frederik Barkhof
Published 2014-01-01

Amyloid-β Load Is Related to Worries, but Not to Severity of Cognitive Complaints in Individuals With Subjective Cognitive Decline: The SCIENCe Project

by Sander C. J. Verfaillie, Sander C. J. Verfaillie, Sander C. J. Verfaillie, Tessa Timmers, Tessa Timmers, Tessa Timmers, Rosalinde E. R. Slot, Rosalinde E. R. Slot, Chris W. J. van der Weijden, Chris W. J. van der Weijden, Linda M. P. Wesselman, Linda M. P. Wesselman, Niels D. Prins, Niels D. Prins, Sietske A. M. Sikkes, Sietske A. M. Sikkes, Sietske A. M. Sikkes, Maqsood Yaqub, Maqsood Yaqub, Annemiek Dols, Annemiek Dols, Annemiek Dols, Adriaan A. Lammertsma, Adriaan A. Lammertsma, Philip Scheltens, Philip Scheltens, Rik Ossenkoppele, Rik Ossenkoppele, Rik Ossenkoppele, Bart N. M. van Berckel, Bart N. M. van Berckel, Wiesje M. van der Flier, Wiesje M. van der Flier, Wiesje M. van der Flier
Published 2019-01-01

Tau PET correlates with different Alzheimer’s disease‐related features compared to CSF and plasma p‐tau biomarkers

by Rik Ossenkoppele, Juhan Reimand, Ruben Smith, Antoine Leuzy, Olof Strandberg, Sebastian Palmqvist, Erik Stomrud, Henrik Zetterberg, the Alzheimer's Disease Neuroimaging Initiative, Philip Scheltens, Jeffrey L Dage, Femke Bouwman, Kaj Blennow, Niklas Mattsson‐Carlgren, Shorena Janelidze, Oskar Hansson
Published 2021-08-01

Hippocampal [18F]flortaucipir BPND corrected for possible spill-in of the choroid plexus retains strong clinico-pathological relationships

by Emma E Wolters, Rik Ossenkoppele, Sandeep SV Golla, Sander CJ Verfaillie, Tessa Timmers, Denise Visser, Hayel Tuncel, Emma M Coomans, Albert D Windhorst, Philip Scheltens, Wiesje M van der Flier, Ronald Boellaard, Bart NM van Berckel
Published 2020-01-01

Time to Amyloid Positivity and Preclinical Changes in Brain Metabolism, Atrophy, and Cognition: Evidence for Emerging Amyloid Pathology in Alzheimer's Disease

by Philip S. Insel, Philip S. Insel, Philip S. Insel, Rik Ossenkoppele, Devon Gessert, William Jagust, William Jagust, Susan Landau, Susan Landau, Oskar Hansson, Oskar Hansson, Michael W. Weiner, Michael W. Weiner, Niklas Mattsson, Niklas Mattsson, Niklas Mattsson, for the Alzheimer's Disease Neuroimaging Initiative
Published 2017-05-01

Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease

by Ellen H. Singleton, Yolande A. L. Pijnenburg, Carole H. Sudre, Colin Groot, Elena Kochova, Frederik Barkhof, Renaud La Joie, Howard J. Rosen, William W. Seeley, Bruce Miller, M. Jorge Cardoso, Janne Papma, Philip Scheltens, Gil D. Rabinovici, Rik Ossenkoppele
Published 2020-11-01

Differential trajectories of hypometabolism across cognitively-defined Alzheimer’s disease subgroups

by Colin Groot, Shannon L. Risacher, J.Q. Alida Chen, Ellen Dicks, Andrew J. Saykin, Christine L. Mac Donald, Jesse Mez, Emily H. Trittschuh, Shubhabrata Mukherjee, Frederik Barkhof, Philip Scheltens, Wiesje M. van der Flier, Rik Ossenkoppele, Paul K. Crane
Published 2021-01-01

A novel partial volume correction method for accurate quantification of [18F] flortaucipir in the hippocampus

by Emma E. Wolters, Sandeep S. V. Golla, Tessa Timmers, Rik Ossenkoppele, Chris W. J. van der Weijden, Philip Scheltens, Lothar Schwarte, Robert C. Schuit, Albert D. Windhorst, Frederik Barkhof, Maqsood Yaqub, Adriaan A. Lammertsma, Ronald Boellaard, Bart N. M. van Berckel
Published 2018-08-01

Disease progression modelling from preclinical Alzheimer’s disease (AD) to AD dementia

by Soo Hyun Cho, Sookyoung Woo, Changsoo Kim, Hee Jin Kim, Hyemin Jang, Byeong C. Kim, Si Eun Kim, Seung Joo Kim, Jun Pyo Kim, Young Hee Jung, Samuel Lockhart, Rik Ossenkoppele, Susan Landau, Duk L. Na, Michael Weiner, Seonwoo Kim, Sang Won Seo
Published 2021-02-01