Membrane lipids define small extracellular vesicle subtypes secreted by mesenchymal stromal cells

by Ruenn Chai Lai, Sai Kiang Lim
Published 2019-02-01

Exosome: A Novel and Safer Therapeutic Refinement of Mesenchymal Stem Cell

by Ronne Wee Yeh Yeo, Ruenn Chai Lai, Kok Hian Tan, Sai Kiang Lim
Published 2013-01-01

Topical Application of Mesenchymal Stem Cell Exosomes Alleviates the Imiquimod Induced Psoriasis-Like Inflammation

by Bin Zhang, Ruenn Chai Lai, Wei Kian Sim, Andre Boon Hwa Choo, Ellen Birgit Lane, Sai Kiang Lim
Published 2021-01-01

Assessment of Tumorigenic Potential in Mesenchymal-Stem/Stromal-Cell-Derived Small Extracellular Vesicles (MSC-sEV)

by Thong Teck Tan, Ruenn Chai Lai, Jayanthi Padmanabhan, Wei Kian Sim, Andre Boon Hwa Choo, Sai Kiang Lim
Published 2021-04-01

Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane

by Soon Sim Tan, Yijun Yin, Tricia Lee, Ruenn Chai Lai, Ronne Wee Yeh Yeo, Bin Zhang, Andre Choo, Sai Kiang Lim
Published 2013-12-01

Human mesenchymal stem cell-derived exosomes promote orderly cartilage regeneration in an immunocompetent rat osteochondral defect model

by Shipin Zhang, Keng Lin Wong, Wern Cui Chu, Ruenn Chai Lai, James Hoi Po Hui, Eng Hin Lee, Sai Kiang Lim, Wei Seong Toh
Published 2016-10-01

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA

by Ruenn Chai Lai, Soon Sim Tan, Ronne Wee Yeh Yeo, Andre Boon Hwa Choo, Agnes T. Reiner, Yan Su, Yang Shen, Zhiyan Fu, Lezhava Alexander, Siu Kwan Sze, Sai Kiang Lim
Published 2016-02-01

Systemic Mesenchymal Stem Cell-Derived Exosomes Reduce Myocardial Infarct Size: Characterization With MRI in a Porcine Model

by Christopher J. Charles, Christopher J. Charles, Christopher J. Charles, Renee R. Li, Renee R. Li, Teresa Yeung, Teresa Yeung, Stephane M. Ibraham Mazlan, Stephane M. Ibraham Mazlan, Ruenn Chai Lai, Dominique P. V. de Kleijn, Sai Kiang Lim, Sai Kiang Lim, A. Mark Richards, A. Mark Richards
Published 2020-11-01

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

by Kenneth W. Witwer, Bas W.M. Van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, Mario Gimona, Andrew F. Hill, Dominique De Kleijn, Mickey Koh, Ruenn Chai Lai, S. Alex Mitsialis, Luis A. Ortiz, Eva Rohde, Takashi Asada, Wei Seong Toh, Daniel J. Weiss, Lei Zheng, Bernd Giebel, Sai Kiang Lim
Published 2019-12-01