Subverting lysosomal function in Trypanosoma brucei

by Sam Alsford
Published 2015-08-01

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis

by Sam Alsford
Published 2014-07-01

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes.

by Lucy Glover, Sam Alsford, David Horn
Published 2013-03-01

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes.

by Martin Zoltner, Ka Fai Leung, Sam Alsford, David Horn, Mark C Field
Published 2015-10-01

Correction: Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes.

by Martin Zoltner, Ka Fai Leung, Sam Alsford, David Horn, Mark C Field
Published 2015-11-01

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

by Rachel B Currier, Anneli Cooper, Hollie Burrell-Saward, Annette MacLeod, Sam Alsford
Published 2018-01-01

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei.

by Sam Alsford, Rachel B Currier, José Afonso Guerra-Assunção, Taane G Clark, David Horn
Published 2014-05-01

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.

by James A Thomas, Nicola Baker, Sebastian Hutchinson, Caia Dominicus, Anna Trenaman, Lucy Glover, Sam Alsford, David Horn
Published 2018-11-01

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.

by Jennifer A Stortz, Tiago D Serafim, Sam Alsford, Jonathan Wilkes, Fernando Fernandez-Cortes, Graham Hamilton, Emma Briggs, Leandro Lemgruber, David Horn, Jeremy C Mottram, Richard McCulloch
Published 2017-07-01

NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.

by Kelly N DuBois, Sam Alsford, Jennifer M Holden, Johanna Buisson, Michal Swiderski, Jean-Mathieu Bart, Alexander V Ratushny, Yakun Wan, Philippe Bastin, J David Barry, Miguel Navarro, David Horn, John D Aitchison, Michael P Rout, Mark C Field
Published 2012-01-01