Applications of the CRISPR-Cas9 system in cancer biology

by Sanchez-Rivera, Francisco Javier, Jacks, Tyler E.
Published 2018

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

by Weintraub, Abraham S., Buenrostro, Jason D., Cheng, Christine S., Regev, Aviv, Young, Richard A., Soto Feliciano, Yadira M., Bartlebaugh, Jordan M. E., Sanchez-Rivera, Francisco Javier, Bhutkar, Arjun, Jacks, Tyler E., Hemann, Michael, Liu, Yunpeng,S.M.Massachusetts Institute of Technology
Published 2018

Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival

by Gocheva, Vasilena, Naba, Alexandra, Bhutkar, Arjun, Guardia, Talia, Miller, Kathryn, Li, Carman Man Chung, Dayton, Talya L., Sanchez-Rivera, Francisco Javier, Kim-Kiselak, Caroline, Jailkhani, Noor, Winslow, Monte Meier, Del Rosario, Amanda M., Hynes, Richard O., Jacks, Tyler E.
Published 2018

In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis

by Taylor, Martin S., Sicinska, Ewa T., Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam J., Tsichlis, Philip N., Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Oberli, Matthias, Sanchez-Rivera, Francisco Javier, Park, Yoona K., Liang, Xu, Eng, George M., Azimi, Roxana S., Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Lees, Jacqueline, Langer, Robert S., Hynes, Richard O., Chen, Jianzhu, Bhutkar, Arjun, Jacks, Tyler E., Yilmaz, Omer
Published 2018

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

by Mazur, Pawel K., Herner, Alexander, Mello, Stephano S., Wirth, Matthias, Hausmann, Simone, Lofgren, Shane M., Kuschma, Timo, Hahn, Stephan A., Vangala, Deepak, Trajkovic-Arsic, Marija, Gupta, Aayush, Heid, Irina, Noel, Peter B., Braren, Rickmer, Erkan, Mert, Kleeff, Jorg, Sipos, Bence, Sayles, Leanne C., Heikenwalder, Mathias, Hessmann, Elizabeth, Ellenrieder, Volker, Esposito, Irene, Bradner, James E., Khatri, Purvesh, Sweet-Cordero, E Alejandro, Attardi, Laura D., Schmid, Roland M., Schneider, Guenter, Sage, Julien, Siveke, Jens T., Sanchez-Rivera, Francisco Javier, Jacks, Tyler E.
Published 2017

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

by Sayin, Volkan I., Singh, Simranjit X., LeBoeuf, Sarah E., Karakousi, Triantafyllia R., Martinez, Britney, Bronson, Roderick T., Prigge, Justin R., Schmidt, Edward E., Thomas, Craig J., Goparaju, Chandra, Davies, Angela, Dolgalev, Igor, Heguy, Adriana, Allaj, Viola, Poirier, John T., Moreira, Andre L., Rudin, Charles M., Pass, Harvey I., Papagiannakopoulos, Thales, Davidson, Shawn M., Bauer, Matthew R., Ellis, Donald Christian, Bhutkar, Arjun, Sanchez-Rivera, Francisco Javier, Subbaraj, Lakshmipriya, Vander Heiden, Matthew G., Jacks, Tyler E., Romero, Rodrigo,Ph. D.Massachusetts Institute of Technology
Published 2018

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

by Katajisto, Pekka, Tammela, Tuomas, Cetinbas, Naniye, Wu, Katherine, Helenius, Katja Piritta, Park, Yoona K, Azimi, Roxana S., Kerper, Natanya R., Wesselhoeft IV, Robert Alexander, Gu, Xin, Schmidt, Leah Marie, Cornwall-Brady, Milton R., Yilmaz, Omer, Xue, Wen, Bhutkar, Arjun, Jacks, Tyler E, Sanchez-Rivera, Francisco Jav, Joshi, Nik
Published 2018