CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects.

by Joyce K Hu, Jordan C Crampton, Michela Locci, Shane Crotty
Published 2016-01-01

Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies.

by Lindsay Crickard, Tahar Babas, Sidharth Seth, Peter Silvera, Lilia Koriazova, Shane Crotty
Published 2012-01-01

IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation.

by Danelle Eto, Christopher Lao, Daniel DiToro, Burton Barnett, Tania C Escobar, Robin Kageyama, Isharat Yusuf, Shane Crotty
Published 2011-03-01

OX40 facilitates control of a persistent virus infection.

by Tobias Boettler, Friedrich Moeckel, Yang Cheng, Maximilian Heeg, Shahram Salek-Ardakani, Shane Crotty, Michael Croft, Matthias G von Herrath
Published 2012-09-01

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

by Jeong Hyun Lee, Laura Toy, Justin T. Kos, Yana Safonova, William R. Schief, Colin Havenar-Daughton, Corey T. Watson, Shane Crotty
Published 2021-09-01

Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf

by Fengyin Li, Zhouhao Zeng, Shaojun Xing, Jodi A. Gullicksrud, Qiang Shan, Jinyong Choi, Vladimir P. Badovinac, Shane Crotty, Weiqun Peng, Hai-Hui Xue
Published 2018-12-01

Correction: Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.

by Ricardo da Silva Antunes, Sinu Paul, John Sidney, Daniela Weiskopf, Jennifer M Dan, Elizabeth Phillips, Simon Mallal, Shane Crotty, Alessandro Sette, Cecilia S Lindestam Arlehamn
Published 2018-01-01

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.

by Ricardo da Silva Antunes, Sinu Paul, John Sidney, Daniela Weiskopf, Jennifer M Dan, Elizabeth Phillips, Simon Mallal, Shane Crotty, Alessandro Sette, Cecilia S Lindestam Arlehamn
Published 2017-01-01

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

by Diane G. Carnathan, Diane G. Carnathan, Diane G. Carnathan, Kirti Kaushik, Ali H. Ellebedy, Ali H. Ellebedy, Ali H. Ellebedy, Chiamaka A. Enemuo, Etse H. Gebru, Pallavi Dhadvai, Mohammed Ata Ur Rasheed, Mohammed Ata Ur Rasheed, Matthias G. Pauthner, Matthias G. Pauthner, Gabriel Ozorowski, Gabriel Ozorowski, Rafi Ahmed, Rafi Ahmed, Dennis R. Burton, Dennis R. Burton, Dennis R. Burton, Andrew B. Ward, Andrew B. Ward, Guido Silvestri, Guido Silvestri, Guido Silvestri, Shane Crotty, Shane Crotty, Shane Crotty, Michela Locci, Michela Locci, Michela Locci
Published 2020-06-01

Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.

by Michael H Matho, Andrew Schlossman, Xiangzhi Meng, Mohammed Rafii-El-Idrissi Benhnia, Thomas Kaever, Mark Buller, Konstantin Doronin, Scott Parker, Bjoern Peters, Shane Crotty, Yan Xiang, Dirk M Zajonc
Published 2015-09-01

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells.

by Samantha Reiss, Amy E Baxter, Kimberly M Cirelli, Jennifer M Dan, Antigoni Morou, Audrey Daigneault, Nathalie Brassard, Guido Silvestri, Jean-Pierre Routy, Colin Havenar-Daughton, Shane Crotty, Daniel E Kaufmann
Published 2017-01-01

Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E.

by Michael H Matho, Natalia de Val, Gregory M Miller, Joshua Brown, Andrew Schlossman, Xiangzhi Meng, Shane Crotty, Bjoern Peters, Yan Xiang, Linda C Hsieh-Wilson, Andrew B Ward, Dirk M Zajonc
Published 2014-12-01

Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

by Dalia E. Gaddis, Lindsey E. Padgett, Runpei Wu, Chantel McSkimming, Veronica Romines, Angela M. Taylor, Coleen A. McNamara, Mitchell Kronenberg, Shane Crotty, Michael J. Thomas, Mary G. Sorci-Thomas, Catherine C. Hedrick
Published 2018-03-01

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

by Sunglim Cho, Hyang-Mi Lee, I-Shing Yu, Youn Soo Choi, Hsi-Yuan Huang, Somaye Sadat Hashemifar, Ling-Li Lin, Mei-Chi Chen, Nikita D. Afanasiev, Aly Azeem Khan, Shu-Wha Lin, Alexander Y. Rudensky, Shane Crotty, Li-Fan Lu
Published 2018-07-01

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

by Amit A. Upadhyay, Robert C. Kauffman, Amber N. Wolabaugh, Alice Cho, Nirav B. Patel, Samantha M. Reiss, Colin Havenar-Daughton, Reem A. Dawoud, Gregory K. Tharp, Iñaki Sanz, Bali Pulendran, Shane Crotty, F. Eun-Hyung Lee, Jens Wrammert, Steven E. Bosinger
Published 2018-03-01

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

by Daniel W. Kulp, Jon M. Steichen, Matthias Pauthner, Xiaozhen Hu, Torben Schiffner, Alessia Liguori, Christopher A. Cottrell, Colin Havenar-Daughton, Gabriel Ozorowski, Erik Georgeson, Oleksandr Kalyuzhniy, Jordan R. Willis, Michael Kubitz, Yumiko Adachi, Samantha M. Reiss, Mia Shin, Natalia de Val, Andrew B. Ward, Shane Crotty, Dennis R. Burton, William R. Schief
Published 2017-11-01

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization

by Colin Havenar-Daughton, Diane G. Carnathan, Archana V. Boopathy, Amit A. Upadhyay, Ben Murrell, Samantha M. Reiss, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Pallavi Dhadvai, Federico Viviano, Kirti Kaushik, Jinal N. Bhiman, Bryan Briney, Dennis R. Burton, Steven E. Bosinger, William R. Schief, Darrell J. Irvine, Guido Silvestri, Shane Crotty
Published 2019-11-01

AI-guided discovery of the invariant host response to viral pandemics

by Debashis Sahoo, Gajanan D. Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire, Vanessa Castillo, Courtney Tindle, MacKenzie Fuller, Sahar Taheri, Thomas F. Rogers, Nathan Beutler, Sydney I. Ramirez, Stephen A. Rawlings, Victor Pretorius, Davey M. Smith, Dennis R. Burton, Laura E. Crotty Alexander, Jason Duran, Shane Crotty, Jennifer M. Dan, Soumita Das, Pradipta Ghosh
Published 2021-06-01

Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2

by Jorge A. Masso-Silva, Jorge A. Masso-Silva, Alexander Moshensky, Alexander Moshensky, John Shin, John Shin, Jarod Olay, Jarod Olay, Sedtavut Nilaad, Sedtavut Nilaad, Ira Advani, Ira Advani, Christine M. Bojanowski, Christine M. Bojanowski, Christine M. Bojanowski, Shane Crotty, Wei Tse Li, Weg M. Ongkeko, Sunit Singla, Laura E. Crotty Alexander, Laura E. Crotty Alexander
Published 2021-05-01

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

by P J Klasse, Thomas J Ketas, Christopher A Cottrell, Gabriel Ozorowski, Gargi Debnath, Diawoye Camara, Erik Francomano, Pavel Pugach, Rajesh P Ringe, Celia C LaBranche, Marit J van Gils, Christine A Bricault, Dan H Barouch, Shane Crotty, Guido Silvestri, Sudhir Kasturi, Bali Pulendran, Ian A Wilson, David C Montefiori, Rogier W Sanders, Andrew B Ward, John P Moore
Published 2018-02-01