Synthetic associations created by rare variants do not explain most GWAS results.

by Naomi R Wray, Shaun M Purcell, Peter M Visscher
Published 2011-01-01

Testing for an unusual distribution of rare variants.

by Benjamin M Neale, Manuel A Rivas, Benjamin F Voight, David Altshuler, Bernie Devlin, Marju Orho-Melander, Sekar Kathiresan, Shaun M Purcell, Kathryn Roeder, Mark J Daly
Published 2011-03-01

mTADA is a framework for identifying risk genes from de novo mutations in multiple traits

by Tan-Hoang Nguyen, Amanda Dobbyn, Ruth C. Brown, Brien P. Riley, Joseph D. Buxbaum, Dalila Pinto, Shaun M. Purcell, Patrick F. Sullivan, Xin He, Eli A. Stahl
Published 2020-06-01

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

by Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin C Y Ng, International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler, Mark J Daly
Published 2009-06-01

The genetic structure of the Swedish population.

by Keith Humphreys, Alexander Grankvist, Monica Leu, Per Hall, Jianjun Liu, Samuli Ripatti, Karola Rehnström, Leif Groop, Lars Klareskog, Bo Ding, Henrik Grönberg, Jianfeng Xu, Nancy L Pedersen, Paul Lichtenstein, Morten Mattingsdal, Ole A Andreassen, Colm O'Dushlaine, Shaun M Purcell, Pamela Sklar, Patrick F Sullivan, Christina M Hultman, Juni Palmgren, Patrik K E Magnusson
Published 2011-01-01

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

by Hoang T. Nguyen, Julien Bryois, April Kim, Amanda Dobbyn, Laura M. Huckins, Ana B. Munoz-Manchado, Douglas M. Ruderfer, Giulio Genovese, Menachem Fromer, Xinyi Xu, Dalila Pinto, Sten Linnarsson, Matthijs Verhage, August B. Smit, Jens Hjerling-Leffler, Joseph D. Buxbaum, Christina Hultman, Pamela Sklar, Shaun M. Purcell, Kasper Lage, Xin He, Patrick F. Sullivan, Eli A. Stahl
Published 2017-12-01

A Role for Noncoding Variation in Schizophrenia

by Panos Roussos, Amanda C. Mitchell, Georgios Voloudakis, John F. Fullard, Venu M. Pothula, Jonathan Tsang, Eli A. Stahl, Anastasios Georgakopoulos, Douglas M. Ruderfer, Alexander Charney, Yukinori Okada, Katherine A. Siminovitch, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Robert M. Plenge, Soumya Raychaudhuri, Menachem Fromer, Shaun M. Purcell, Kristen J. Brennand, Nikolaos K. Robakis, Eric E. Schadt, Schahram Akbarian, Pamela Sklar
Published 2014-11-01

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

by Esperanza Fernández, Mark O. Collins, René A.W. Frank, Fei Zhu, Maksym V. Kopanitsa, Jess Nithianantharajah, Sarah A. Lemprière, David Fricker, Kathryn A. Elsegood, Catherine L. McLaughlin, Mike D.R. Croning, Colin Mclean, J. Douglas Armstrong, W. David Hill, Ian J. Deary, Giulia Cencelli, Claudia Bagni, Menachem Fromer, Shaun M. Purcell, Andrew J. Pocklington, Jyoti S. Choudhary, Noboru H. Komiyama, Seth G.N. Grant
Published 2017-10-01

Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

by Hassan S. Dashti, Samuel E. Jones, Andrew R. Wood, Jacqueline M. Lane, Vincent T. van Hees, Heming Wang, Jessica A. Rhodes, Yanwei Song, Krunal Patel, Simon G. Anderson, Robin N. Beaumont, David A. Bechtold, Jack Bowden, Brian E. Cade, Marta Garaulet, Simon D. Kyle, Max A. Little, Andrew S. Loudon, Annemarie I. Luik, Frank A. J. L. Scheer, Kai Spiegelhalder, Jessica Tyrrell, Daniel J. Gottlieb, Henning Tiemeier, David W. Ray, Shaun M. Purcell, Timothy M. Frayling, Susan Redline, Deborah A. Lawlor, Martin K. Rutter, Michael N. Weedon, Richa Saxena
Published 2019-03-01

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

by Brian E. Cade, Jiwon Lee, Tamar Sofer, Heming Wang, Man Zhang, Han Chen, Sina A. Gharib, Daniel J. Gottlieb, Xiuqing Guo, Jacqueline M. Lane, Jingjing Liang, Xihong Lin, Hao Mei, Sanjay R. Patel, Shaun M. Purcell, Richa Saxena, Neomi A. Shah, Daniel S. Evans, Craig L. Hanis, David R. Hillman, Sutapa Mukherjee, Lyle J. Palmer, Katie L. Stone, Gregory J. Tranah, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Gonçalo R. Abecasis, Eric A. Boerwinkle, Adolfo Correa, L. Adrienne Cupples, Robert C. Kaplan, Deborah A. Nickerson, Kari E. North, Bruce M. Psaty, Jerome I. Rotter, Stephen S. Rich, Russell P. Tracy, Ramachandran S. Vasan, James G. Wilson, Xiaofeng Zhu, Susan Redline, TOPMed Sleep Working Group
Published 2021-08-01

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

by Heming Wang, Jacqueline M. Lane, Samuel E. Jones, Hassan S. Dashti, Hanna M. Ollila, Andrew R. Wood, Vincent T. van Hees, Ben Brumpton, Bendik S. Winsvold, Katri Kantojärvi, Teemu Palviainen, Brian E. Cade, Tamar Sofer, Yanwei Song, Krunal Patel, Simon G. Anderson, David A. Bechtold, Jack Bowden, Richard Emsley, Simon D. Kyle, Max A. Little, Andrew S. Loudon, Frank A. J. L. Scheer, Shaun M. Purcell, Rebecca C. Richmond, Kai Spiegelhalder, Jessica Tyrrell, Xiaofeng Zhu, Christer Hublin, Jaakko A. Kaprio, Kati Kristiansson, Sonja Sulkava, Tiina Paunio, Kristian Hveem, Jonas B. Nielsen, Cristen J. Willer, John-Anker Zwart, Linn B. Strand, Timothy M. Frayling, David Ray, Deborah A. Lawlor, Martin K. Rutter, Michael N. Weedon, Susan Redline, Richa Saxena
Published 2019-08-01

Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes

by Ole Kristian Drange, Ole Kristian Drange, Olav Bjerkehagen Smeland, Olav Bjerkehagen Smeland, Alexey A. Shadrin, Per Ivar Finseth, Aree Witoelar, Aree Witoelar, Oleksandr Frei, Psychiatric Genomics Consortium Bipolar Disorder Working Group, Yunpeng Wang, Yunpeng Wang, Sahar Hassani, Sahar Hassani, Srdjan Djurovic, Srdjan Djurovic, Anders M. Dale, Anders M. Dale, Anders M. Dale, Ole A. Andreassen, Ole A. Andreassen, Eli A Stahl, Eli A Stahl, Eli A Stahl, Eli A Stahl, Gerome Breen, Gerome Breen, Gerome Breen, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andrew McQuillin, Andrew McQuillin, Stephan Ripke, Stephan Ripke, Stephan Ripke, Stephan Ripke, Vassily Trubetskoy, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Yunpeng Wang, Yunpeng Wang, Jonathan R I Coleman, Jonathan R I Coleman, Heìleìna A Gaspar, Heìleìna A Gaspar, Christiaan A de Leeuw, Stacy Steinberg, Jennifer M Whitehead Pavlides, Maciej Trzaskowski, Tune H Pers, Tune H Pers, Peter A Holmans, Liam Abbott, Esben Agerbo, Esben Agerbo, Esben Agerbo, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Thomas D Als, Thomas D Als, Thomas D Als, Adebayo Anjorin, Verneri Antilla, Swapnil Awasthi, Judith A Badner, Marie Bækvad-Hansen, Marie Bækvad-Hansen, Jack D Barchas, Nicholas Bass, Michael Bauer, Richard Belliveau, Sarah E Bergen, Carsten Bøcker Pedersen, Carsten Bøcker Pedersen, Carsten Bøcker Pedersen, Erlend Bøen, Marco Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Jonas Bybjerg-Grauholm, Jonas Bybjerg-Grauholm, William Byerley, Miquel Casas, Miquel Casas, Miquel Casas, Miquel Casas, Felecia Cerrato, Pablo Cervantes, Kimberly Chambert, Alexander W Charney, Danfeng Chen, Claire Churchhouse, Claire Churchhouse, Toni-Kim Clarke, William Coryell, David W Craig, Cristiana Cruceanu, Cristiana Cruceanu, David Curtis, David Curtis, Piotr M Czerski, Anders M Dale, Anders M Dale, Anders M Dale, Anders M Dale, Simone de Jong, Simone de Jong, Franziska Degenhardt, Franziska Degenhardt, Jurgen Del-Favero, J Raymond DePaulo, Srdjan Djurovic, Srdjan Djurovic, Amanda L Dobbyn, Amanda L Dobbyn, Ashley Dumont, Torbjørn Elvsåshagen, Torbjørn Elvsåshagen, Valentina Escott-Price, Chun Chieh Fan, Sascha B Fischer, Sascha B Fischer, Matthew Flickinger, Tatiana M Foroud, Liz Forty, Josef Frank, Christine Fraser, Nelson B Freimer, Louise Friseìn, Louise Friseìn, Louise Friseìn, Katrin Gade, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Marianne Giørtz Pedersen, Marianne Giørtz Pedersen, Marianne Giørtz Pedersen, Jaqueline Goldstein, Scott D Gordon, Katherine Gordon-Smith, Elaine K Green, Melissa J Green, Tiffany A Greenwood, Jakob Grove, Jakob Grove, Jakob Grove, Jakob Grove, Weihua Guan, Joseì Guzman Parra, Marian L Hamshere, Martin Hautzinger, Urs Heilbronner, Stefan Herms, Stefan Herms, Stefan Herms, Stefan Herms, Maria Hipolito, Per Hoffmann, Per Hoffmann, Per Hoffmann, Per Hoffmann, Dominic Holland, Dominic Holland, Laura Huckins, Laura Huckins, Steìphane Jamain, Steìphane Jamain, Jessica S Johnson, Jessica S Johnson, Anders Jureìus, Radhika Kandaswamy, Robert Karlsson, James L Kennedy, James L Kennedy, James L Kennedy, James L Kennedy, Sarah Kittel-Schneider, Sarah V Knott, James A Knowles, James A Knowles, Manolis Kogevinas, Anna C Koller, Anna C Koller, Ralph Kupka, Ralph Kupka, Ralph Kupka, Catharina Lavebratt, Jacob Lawrence, William B Lawson, Markus Leber, Phil H Lee, Phil H Lee, Phil H Lee, Shawn E Levy, Jun Z Li, Chunyu Liu, Susanne Lucae, Anna Maaser, Anna Maaser, Donald J MacIntyre, Donald J MacIntyre, Pamela B Mahon, Pamela B Mahon, Wolfgang Maier, Lina Martinsson, Steve McCarroll, Steve McCarroll, Peter McGuffin, Melvin G McInnis, James D McKay, Helena Medeiros, Sarah E Medland, Fan Meng, Fan Meng, Lili Milani, Grant W Montgomery, Derek W Morris, Derek W Morris, Thomas W Mühleisen, Thomas W Mühleisen, Niamh Mullins, Hoang Nguyen, Hoang Nguyen, Caroline M Nievergelt, Caroline M Nievergelt, Annelie Nordin Adolfsson, Evaristus A Nwulia, Claire O’Donovan, Loes M Olde Loohuis, Anil P S Ori, Lilijana Oruc, Urban Ösby, Roy H Perlis, Roy H Perlis, Amy Perry, Andrea Pfennig, James B Potash, Shaun M Purcell, Shaun M Purcell, Eline J Regeer, Andreas Reif, Ceìline S Reinbold, Ceìline S Reinbold, John P Rice, Fabio Rivas, Margarita Rivera, Margarita Rivera, Panos Roussos, Panos Roussos, Panos Roussos, Douglas M Ruderfer, Euijung Ryu, Cristina Saìnchez-Mora, Cristina Saìnchez-Mora, Cristina Saìnchez-Mora, Alan F Schatzberg, William A Scheftner, Nicholas J Schork, Cynthia Shannon Weickert, Cynthia Shannon Weickert, Tatyana Shehktman, Paul D Shilling, Engilbert Sigurdsson, Claire Slaney, Olav B Smeland, Olav B Smeland, Olav B Smeland, Janet L Sobell, Christine Søholm Hansen, Christine Søholm Hansen, Anne T Spijker, David St Clair, Michael Steffens, John S Strauss, John S Strauss, Fabian Streit, Jana Strohmaier, Szabolcs Szelinger, Robert C Thompson, Thorgeir E Thorgeirsson, Jens Treutlein, Helmut Vedder, Weiqing Wang, Weiqing Wang, Stanley J Watson, Thomas W Weickert, Thomas W Weickert, Stephanie H Witt, Simon Xi, Wei Xu, Wei Xu, Allan H Young, Peter Zandi, Peng Zhang, Sebastian Zollner, Rolf Adolfsson, Ingrid Agartz, Ingrid Agartz, Ingrid Agartz, Martin Alda, Martin Alda, Lena Backlund, Bernhard T Baune, Frank Bellivier, Frank Bellivier, Frank Bellivier, Frank Bellivier, Wade H Berrettini, Joanna M Biernacka, Douglas H R Blackwood, Michael Boehnke, Anders D Børglum, Anders D Børglum, Anders D Børglum, Aiden Corvin, Nicholas Craddock, Mark J Daly, Mark J Daly, Udo Dannlowski, ToÞnu Esko, ToÞnu Esko, ToÞnu Esko, ToÞnu Esko, Bruno Etain, Bruno Etain, Bruno Etain, Bruno Etain, Mark Frye, Janice M Fullerton, Janice M Fullerton, Elliot S Gershon, Elliot S Gershon, Michael Gill, Fernando Goes, Maria Grigoroiu-Serbanescu, Joanna Hauser, David M Hougaard, David M Hougaard, Christina M Hultman, Ian Jones, Lisa A Jones, Reneì S Kahn, Reneì S Kahn, George Kirov, Mikael Landeìn, Mikael Landeìn, Marion Leboyer, Marion Leboyer, Marion Leboyer, Cathryn M Lewis, Cathryn M Lewis, Cathryn M Lewis, Qingqin S Li, Jolanta Lissowska, Nicholas G Martin, Nicholas G Martin, Fermin Mayoral, Susan L McElroy, Andrew M McIntosh, Andrew M McIntosh, Francis J McMahon, Ingrid Melle, Ingrid Melle, Andres Metspalu, Andres Metspalu, Philip B Mitchell, Gunnar Morken, Gunnar Morken, Ole Mors, Ole Mors, Preben Bo Mortensen, Preben Bo Mortensen, Preben Bo Mortensen, Preben Bo Mortensen, Bertram Müller-Myhsok, Bertram Müller-Myhsok, Bertram Müller-Myhsok, Richard M Myers, Benjamin M Neale, Benjamin M Neale, Benjamin M Neale, Vishwajit Nimgaonkar, Merete Nordentoft, Merete Nordentoft, Markus M Nöthen, Markus M Nöthen, Michael C O’Donovan, Ketil J Oedegaard, Ketil J Oedegaard, Michael J Owen, Sara A Paciga, Carlos Pato, Carlos Pato, Michele T Pato, Danielle Posthuma, Danielle Posthuma, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Marta Ribaseìs, Marta Ribaseìs, Marta Ribaseìs, Marcella Rietschel, Guy A Rouleau, Guy A Rouleau, Martin Schalling, Peter R Schofield, Peter R Schofield, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Alessandro Serretti, Jordan W Smoller, Jordan W Smoller, Jordan W Smoller, Hreinn Stefansson, Kari Stefansson, Kari Stefansson, Eystein Stordal, Eystein Stordal, Patrick F Sullivan, Patrick F Sullivan, Patrick F Sullivan, Gustavo Turecki, Arne E Vaaler, Eduard Vieta, John B Vincent, Thomas Werge, Thomas Werge, Thomas Werge, John I Nurnberger, Naomi R Wray, Naomi R Wray, Arianna Di Florio, Arianna Di Florio, Howard J Edenberg, Sven Cichon, Sven Cichon, Sven Cichon, Sven Cichon, Roel A Ophoff, Roel A Ophoff, Roel A Ophoff, Laura J Scott, Ole A Andreassen, Ole A Andreassen, John Kelsoe, John Kelsoe, Pamela Sklar, Pamela Sklar, Pamela Sklar, Pamela Sklar
Published 2019-03-01