Principles of Immunotherapy: Implications for Treatment Strategies in Cancer and Infectious Diseases

by Krupa Naran, Trishana Nundalall, Shivan Chetty, Stefan Barth, Stefan Barth
Published 2018-12-01

Human Granzyme B Based Targeted Cytolytic Fusion Proteins

by Precious Hlongwane, Neelakshi Mungra, Suresh Madheswaran, Olusiji A. Akinrinmade, Shivan Chetty, Stefan Barth
Published 2018-06-01

HIV-1 Subtype C Mosaic Gag Expressed by BCG and MVA Elicits Persistent Effector T Cell Responses in a Prime-Boost Regimen in Mice.

by Tsungai Ivai Jongwe, Ros Chapman, Nicola Douglass, Shivan Chetty, Gerald Chege, Anna-Lise Williamson
Published 2016-01-01

Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins

by Mehmet Kemal Tur, Adebukola K. Daramola, Stefan Gattenlöhner, Marco Herling, Shivan Chetty, Stefan Barth
Published 2017-10-01

CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases

by Olusiji A. Akinrinmade, Shivan Chetty, Adebukola K. Daramola, Mukit-ul Islam, Theo Thepen, Stefan Barth
Published 2017-09-01

Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells

by Sandra Jordaan, Olusiji A. Akinrinmade, Thomas Nachreiner, Christian Cremer, Krupa Naran, Shivan Chetty, Stefan Barth
Published 2018-03-01

Human MAP Tau Based Targeted Cytolytic Fusion Proteins

by Olusiji A. Akinrinmade, Sandra Jordaan, Dmitrij Hristodorov, Radoslav Mladenov, Neelakshi Mungra, Shivan Chetty, Stefan Barth
Published 2017-06-01

Designing the Sniper: Improving Targeted Human Cytolytic Fusion Proteins for Anti-Cancer Therapy via Molecular Simulation

by Anna Bochicchio, Sandra Jordaan, Valeria Losasso, Shivan Chetty, Rodrigo Casasnovas Perera, Emiliano Ippoliti, Stefan Barth, Paolo Carloni
Published 2017-02-01

Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality.

by Shivan Chetty, Pamla Govender, Jennifer Zupkosky, Mona Pillay, Musie Ghebremichael, Mahomed-Yunus S Moosa, Thumbi Ndung'u, Filippos Porichis, Victoria O Kasprowicz
Published 2015-01-01

Prospective monitoring reveals dynamic levels of T cell immunity to Mycobacterium tuberculosis in HIV infected individuals.

by Jessica E Mitchell, Shivan Chetty, Pamla Govender, Mona Pillay, Manjeetha Jaggernath, Anne Kasmar, Thumbi Ndung'u, Paul Klenerman, Bruce D Walker, Victoria O Kasprowicz
Published 2012-01-01

A molecular assay for sensitive detection of pathogen-specific T-cells.

by Victoria O Kasprowicz, Jessica E Mitchell, Shivan Chetty, Pamla Govender, Kuan-Hsiang Gary Huang, Helen A Fletcher, Daniel P Webster, Sebastian Brown, Anne Kasmar, Kerry Millington, Cheryl L Day, Nompumelelo Mkhwanazi, Cheryl McClurg, Fundisiwe Chonco, Ajit Lalvani, Bruce D Walker, Thumbi Ndung'u, Paul Klenerman
Published 2011-01-01