Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

by Jonas Goldin Diness, Lea Abildgaard, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Mark Alexander Skarsfeldt, Mark Alexander Skarsfeldt, Nils Edvardsson, Nils Edvardsson, Ulrik S. Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Bo Hjorth Bentzen
Published 2020-05-01

Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.

by Maria A Tejada, Kathleen Stople, Sofia Hammami Bomholtz, Anne-Kristine Meinild, Asser Nyander Poulsen, Dan A Klaerke
Published 2014-01-01

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

by Jeppe Egedal Kirchhoff, Mark Alexander Skarsfeldt, Kalai Mangai Muthukumarasamy, Rafel Simó-Vicens, Rafel Simó-Vicens, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Lea Abildgaard, Thomas Jespersen, Ulrik S. Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Bo Hjorth Bentzen, Jonas Goldin Diness
Published 2019-06-01

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

by Bo Hjorth Bentzen, Bo Hjorth Bentzen, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Rafel Simó-Vicens, Rafel Simó-Vicens, Lasse Folkersen, Lea Abildgaard, Tobias Speerschneider, Tobias Speerschneider, Kalai Mangai Muthukumarasamy, Nils Edvardsson, Nils Edvardsson, Ulrik S. Sørensen, Morten Grunnet, Jonas Goldin Diness
Published 2020-05-01

PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

by Annette Buur Steffensen, Sofia Hammami Bomholtz, Martin Nybo Andersen, Jesper Velgaard Olsen, Nancy Mutsaers, Pia Rengtved Lundegaard, Alicia Lundby, Nicole Schmitt
Published 2018-06-01