Mechanistic insights into the inhibition of NTCP by myrcludex B

by Joanne M. Donkers, Monique D. Appelman, Stan F.J. van de Graaf
Published 2019-10-01

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

by Monique D Appelman, Anindita Chakraborty, Ulrike Protzer, Jane A McKeating, Stan F J van de Graaf
Published 2017-01-01

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

by Sandra M.W. van de Wiel, D. Rudi de Waart, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Published 2018-01-01

Thiopurines correct the effects of autophagy impairment on intestinal healing – a potential role for ARHGAP18/RhoA

by Marileen M. C. Prins, Francesca P. Giugliano, Manon van Roest, Stan F. J. van de Graaf, Pim J. Koelink, Manon E. Wildenberg
Published 2021-04-01

An Exon-Specific Small Nuclear U1 RNA (ExSpeU1) Improves Hepatic OTC Expression in a Splicing-Defective <i>spf</i>/<i>ash</i> Mouse Model of Ornithine Transcarbamylase Deficiency

by Dario Balestra, Mattia Ferrarese, Silvia Lombardi, Nicole Ziliotto, Alessio Branchini, Naomi Petersen, Piter Bosma, Mirko Pinotti, Stan F. J. van de Graaf
Published 2020-11-01

A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I

by Dario Balestra, Daniela Scalet, Mattia Ferrarese, Silvia Lombardi, Nicole Ziliotto, Chrystal C. Croes, Naomi Petersen, Piter Bosma, Federico Riccardi, Franco Pagani, Mirko Pinotti, Stan F. J. van de Graaf
Published 2020-03-01

Mutational analysis of ATP8B1 in patients with chronic pancreatitis.

by Wendy L van der Woerd, Désirée Y van Haaften-Visser, Stan F J van de Graaf, Claude Férec, Emmanuelle Masson, Janneke M Stapelbroek, Peter Bugert, Heiko Witt, Roderick H J Houwen
Published 2013-01-01

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces ObesitySummary

by Joanne M. Donkers, Reinout L.P. Roscam Abbing, Michel van Weeghel, Johannes H.M. Levels, Anita Boelen, Alfred H. Schinkel, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Published 2020-01-01

The Lipid Raft Component Stomatin Interacts with the Na⁺ Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake

by Monique D. Appelman, Marion J.D. Robin, Esther W.M. Vogels, Christie Wolzak, Winnie G. Vos, Harmjan R. Vos, Robert M. Van Es, Boudewijn M.T. Burgering, Stan F.J. Van de Graaf
Published 2020-04-01

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+‐Taurocholate Cotransporting Polypeptide

by Marion J.D. Robin, Monique D. Appelman, Harmjan R. Vos, Robert M. van Es, James C. Paton, Adrienne W. Paton, Boudewijn Burgering, Peter Fickert, Jarom Heijmans, Stan F.J. van de Graaf
Published 2018-12-01