Recent advances in understanding myelofibrosis and essential thrombocythemia [version 1; referees: 2 approved]

by William Vainchenker, Stefan N. Constantinescu, Isabelle Plo
Published 2016-04-01

Functional Consequences of Mutations in Myeloproliferative Neoplasms

by Stefan N. Constantinescu, William Vainchenker, Gabriel Levy, Nicolas Papadopoulos
Published 2021-06-01

JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitors.

by Alexandra Dusa, Céline Mouton, Christian Pecquet, Murielle Herman, Stefan N Constantinescu
Published 2010-01-01

JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders [version 1; referees: 2 approved]

by William Vainchenker, Emilie Leroy, Laure Gilles, Caroline Marty, Isabelle Plo, Stefan N. Constantinescu
Published 2018-01-01

Neurobiology of Vascular Dementia

by Ana-Maria Enciu, Stefan N. Constantinescu, Laurenţiu M. Popescu, Dafin F. Mureşanu, Bogdan O. Popescu
Published 2011-01-01

A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation.

by Rodolphe Besancenot, Ronan Chaligné, Carole Tonetti, Florence Pasquier, Caroline Marty, Yann Lécluse, William Vainchenker, Stefan N Constantinescu, Stéphane Giraudier
Published 2010-09-01

Glycines from the APP GXXXG/GXXXA transmembrane motifs promote formation of pathogenic Aβ oligomers in cells

by Marie eDecock, Serena eStanga, Jean-Noël eOctave, Ilse eDewachter, Steven O Smith, Stefan N Constantinescu, Pascal eKienlen-Campard
Published 2016-05-01

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

by Florian Perrin, Nicolas Papadopoulos, Nuria Suelves, Rémi Opsomer, Devkee M. Vadukul, Céline Vrancx, Steven O. Smith, Didier Vertommen, Pascal Kienlen-Campard, Stefan N. Constantinescu
Published 2021-02-01

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

by Florian Perrin, Nicolas Papadopoulos, Nuria Suelves, Rémi Opsomer, Devkee M. Vadukul, Céline Vrancx, Steven O. Smith, Didier Vertommen, Pascal Kienlen-Campard, Stefan N. Constantinescu
Published 2020-12-01

Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN

by Camélia Benlabiod, Maira da Costa Cacemiro, Audrey Nédélec, Valérie Edmond, Delphine Muller, Philippe Rameau, Laure Touchard, Patrick Gonin, Stefan N. Constantinescu, Hana Raslova, Jean-Luc Villeval, William Vainchenker, Isabelle Plo, Caroline Marty
Published 2020-09-01

Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms

by Lise Secardin, Cintia Gomez Limia, Suzana da Silva-Benedito, Larissa Lordier, Mira El-Khoury, Caroline Marty, Jean-Christophe Ianotto, Hana Raslova, Stefan N. Constantinescu, Martín Hernán Bonamino, William Vainchenker, Barbara Monte-Mor, Antonio Di Stefano, Isabelle Plo
Published 2021-07-01

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

by Adam J. Mead, Shabnam Kharazi, Deborah Atkinson, Iain Macaulay, Christian Pecquet, Stephen Loughran, Michael Lutteropp, Petter Woll, Onima Chowdhury, Sidinh Luc, Natalija Buza-Vidas, Helen Ferry, Sally-Ann Clark, Nicolas Goardon, Paresh Vyas, Stefan N. Constantinescu, Ewa Sitnicka, Claus Nerlov, Sten Eirik W. Jacobsen
Published 2013-06-01

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions

by Peter Valent, Alberto Orfao, Stefan Kubicek, Philipp Staber, Torsten Haferlach, Michael Deininger, Karoline Kollmann, Thomas Lion, Irene Virgolini, Georg Winter, Oliver Hantschel, Lukas Kenner, Johannes Zuber, Florian Grebien, Richard Moriggl, Gregor Hoermann, Olivier Hermine, Michael Andreeff, Christoph Bock, Tariq Mughal, Stefan N. Constantinescu, Robert Kralovics, Veronika Sexl, Radek Skoda, Giulio Superti-Furga, Ulrich Jäger
Published 2021-03-01