Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice

by Khaled S. Abd-Elrahman, Stephen S. G. Ferguson
Published 2019-04-01

Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer’s disease mouse models

by Khaled S. Abd-Elrahman, Alison Hamilton, Maryam Vasefi, Stephen S. G. Ferguson
Published 2018-04-01

mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington’s disease

by Jéssica M. de Souza, Khaled S. Abd-Elrahman, Fabiola M. Ribeiro, Stephen S. G. Ferguson
Published 2020-08-01

Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation

by Lorena Bianchine Areal, Alison Hamilton, Cristina Martins-Silva, Rita Gomes Wanderley Pires, Stephen S. G. Ferguson
Published 2019-02-01

Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model

by Alison Hamilton, Maryam Vasefi, Cheryl Vander Tuin, Robyn J. McQuaid, Hymie Anisman, Stephen S.G. Ferguson
Published 2016-05-01

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures.

by Fabiana A Caetano, Brennan S Dirk, Joshua H K Tam, P Craig Cavanagh, Maria Goiko, Stephen S G Ferguson, Stephen H Pasternak, Jimmy D Dikeakos, John R de Bruyn, Bryan Heit
Published 2015-12-01