GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation

by Steve Poirier, Maya Mamarbachi, Wan-Ting Chen, Amy S. Lee, Gaetan Mayer
Published 2015-12-01

Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal Domain.

by Steve Poirier, Hocine Ait Hamouda, Louis Villeneuve, Annie Demers, Gaétan Mayer
Published 2016-01-01

The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice.

by Francois Leblond, Steve Poirier, Carol Yu, Natacha Duquette, Gaetan Mayer, Eric Thorin
Published 2014-01-01

Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.

by Nabil G Seidah, Steve Poirier, Maxime Denis, Rex Parker, Bowman Miao, Claudio Mapelli, Annik Prat, Hanny Wassef, Jean Davignon, Katherine A Hajjar, Gaétan Mayer
Published 2012-01-01