Plasticity of Synaptic Transmission in Human Stem Cell-Derived Neural Networks

by Yi Dong, Man Xiong, Yuejun Chen, Yezheng Tao, Xiang Li, Anita Bhattacharyya, Su-Chun Zhang
Published 2020-02-01

Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo

by Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J. Maragakis, Guo-li Ming, Hong Chen, Su-Chun Zhang
Published 2017-04-01

Impaired lipid metabolism in astrocytes underlies degeneration of cortical projection neurons in hereditary spastic paraplegia

by Yongchao Mou, Yi Dong, Zhenyu Chen, Kyle R. Denton, Michael O. Duff, Craig Blackstone, Su-Chun Zhang, Xue-Jun Li
Published 2020-12-01

Intracerebral Transplantation of Differentiated Human Embryonic Stem Cells to Hemiparkinsonian Monkeys

by Marina E. Emborg M.D., Ph.D., Zhijian Zhang, Valerie Joers, Kevin Brunner, Viktorya Bondarenko, Sachiko Ohshima, Su-Chun Zhang
Published 2013-05-01

Generation of Integration-free and Region-Specific Neural Progenitors from Primate Fibroblasts

by Jianfeng Lu, Huisheng Liu, Cindy Tzu-Ling Huang, Hong Chen, Zhongwei Du, Yan Liu, Mohammad Amin Sherafat, Su-Chun Zhang
Published 2013-05-01

Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds

by Yingnan Yin, Andrew J. Petersen, Cheryl Soref, William D. Richards, Tenneille Ludwig, Seth Taapken, Erich Berndt, Su-Chun Zhang, Anita Bhattacharyya
Published 2019-01-01

Induced Pluripotent Stem Cell-Derived Neural Cells Survive and Mature in the Nonhuman Primate Brain

by Marina E. Emborg, Yan Liu, Jiajie Xi, Xiaoqing Zhang, Yingnan Yin, Jianfeng Lu, Valerie Joers, Christine Swanson, James E. Holden, Su-Chun Zhang
Published 2013-03-01

Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

by Liqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann, Jeffrey R. Jones, Ernest Fraenkel, David A. Weitz, Su-Chun Zhang, Albee Messing, Mel B. Feany
Published 2018-05-01

Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons

by Hai-Qin Huo, Zhuang-Yin Qu, Fang Yuan, Lixiang Ma, Lin Yao, Min Xu, Yao Hu, Jing Ji, Anita Bhattacharyya, Su-Chun Zhang, Yan Liu
Published 2018-04-01

Widespread sequence variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins.

by Lisheng Peng, Michael Adler, Ann Demogines, Andrew Borrell, Huisheng Liu, Liang Tao, William H Tepp, Su-Chun Zhang, Eric A Johnson, Sara L Sawyer, Min Dong
Published 2014-07-01

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

by Giulia E. Tyzack, Claire E. Hall, Christopher R. Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F. Meyer, Giampietro Schiavo, Su-Chun Zhang, George M. Gibbons, Jia Newcombe, Rickie Patani, András Lakatos
Published 2017-10-01

Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells

by Xiang Li, Yezheng Tao, Robert Bradley, Zhongwei Du, Yunlong Tao, Linghai Kong, Yi Dong, Jeffrey Jones, Yuanwei Yan, Cole R.K. Harder, Lindsay Morgan Friedman, Magd Bilal, Brianna Hoffmann, Su-Chun Zhang
Published 2018-10-01

[ 18F]FEPPA PET imaging for monitoring CD68-positive microglia/macrophage neuroinflammation in nonhuman primates

by Matthew Zammit, Yunlong Tao, Miles E. Olsen, Jeanette Metzger, Scott C. Vermilyea, Kathryn Bjornson, Maxim Slesarev, Walter F. Block, Kerri Fuchs, Sean Phillips, Viktorya Bondarenko, Su-Chun Zhang, Marina E. Emborg, Bradley T. Christian
Published 2020-08-01

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes

by Jeffrey R. Jones, Linghai Kong, Michael G. Hanna, IV, Brianna Hoffman, Robert Krencik, Robert Bradley, Tracy Hagemann, Jeea Choi, Matthew Doers, Marina Dubovis, Mohammad Amin Sherafat, Anita Bhattacharyya, Christina Kendziorski, Anjon Audhya, Albee Messing, Su-Chun Zhang
Published 2018-10-01

Real-Time Intraoperative MRI Intracerebral Delivery of Induced Pluripotent Stem Cell-Derived Neurons

by Scott C. Vermilyea, Jianfeng Lu, Miles Olsen, Scott Guthrie, Yunlong Tao, Eva M. Fekete, Marissa K. Riedel, Kevin Brunner, Carissa Boettcher, Viktorya Bondarenko, Ethan Brodsky, Walter F. Block, Andrew Alexander, Su-Chun Zhang, Marina E. Emborg M.D., Ph.D.
Published 2017-04-01

Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury

by ChenZi Gong, Xiaolong Zheng, FangLiang Guo, YaNan Wang, Song Zhang, Jing Chen, XueJiao Sun, Sayed Zulfiqar Ali Shah, YiFeng Zheng, Xiao Li, Yatao Yin, Qian Li, XiaoLin Huang, Tiecheng Guo, Xiaohua Han, Su-Chun Zhang, Wei Wang, Hong Chen
Published 2021-03-01

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

by Minna Oksanen, Andrew J. Petersen, Nikolay Naumenko, Katja Puttonen, Šárka Lehtonen, Max Gubert Olivé, Anastasia Shakirzyanova, Stina Leskelä, Timo Sarajärvi, Matti Viitanen, Juha O. Rinne, Mikko Hiltunen, Annakaisa Haapasalo, Rashid Giniatullin, Pasi Tavi, Su-Chun Zhang, Katja M. Kanninen, Riikka H. Hämäläinen, Jari Koistinaho
Published 2017-12-01