Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.

by Timothy A Vickers, Susan M Freier, Huynh-Hoa Bui, Andrew Watt, Stanley T Crooke
Published 2014-01-01

Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration

by Sarah D. Diermeier, Kung-Chi Chang, Susan M. Freier, Junyan Song, Osama El Demerdash, Alexander Krasnitz, Frank Rigo, C. Frank Bennett, David L. Spector
Published 2016-09-01

Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB.

by Vidisha Tripathi, Zhen Shen, Arindam Chakraborty, Sumanprava Giri, Susan M Freier, Xiaolin Wu, Yongqing Zhang, Myriam Gorospe, Supriya G Prasanth, Ashish Lal, Kannanganattu V Prasanth
Published 2013-03-01

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.

by Lulu Huang, Sagar S Damle, Sheri Booten, Priyam Singh, Mahyar Sabripour, Jeff Hsu, Minji Jo, Melanie Katz, Andy Watt, Christopher E Hart, Susan M Freier, Brett P Monia, Shuling Guo
Published 2015-01-01

A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability.

by Mahdieh Jadaliha, Omid Gholamalamdari, Wei Tang, Yang Zhang, Ana Petracovici, Qinyu Hao, Aamira Tariq, Tae Gyoon Kim, Sarah E Holton, Deepak K Singh, Xiao Ling Li, Susan M Freier, Stefan Ambs, Rohit Bhargava, Ashish Lal, Supriya G Prasanth, Jian Ma, Kannanganattu V Prasanth
Published 2018-11-01

Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients.

by Niels H Skotte, Amber L Southwell, Michael E Østergaard, Jeffrey B Carroll, Simon C Warby, Crystal N Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T Watt, Susan M Freier, Gene Hung, Punit P Seth, C Frank Bennett, Eric E Swayze, Michael R Hayden
Published 2014-01-01

Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer

by Sudhanshu Shukla, Xiang Zhang, Yashar S. Niknafs, Lanbo Xiao, Rohit Mehra, Marcin Cieślik, Ashley Ross, Edward Schaeffer, Bhavna Malik, Shuling Guo, Susan M. Freier, Huynh-Hoa Bui, Javed Siddiqui, Xiaojun Jing, Xuhong Cao, Saravana M. Dhanasekaran, Felix Y. Feng, Arul M. Chinnaiyan, Rohit Malik
Published 2016-08-01