Longitudinal stability of urinary extracellular vesicle protein patterns within and between individuals

by Leyla A. Erozenci, Sander R. Piersma, Thang V. Pham, Irene V. Bijnsdorp, Connie R. Jimenez
Published 2021-08-01

Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

by Irene V. Bijnsdorp, Olga Maxouri, Aarzo Kardar, Tim Schelfhorst, Sander R. Piersma, Thang V. Pham, Andre Vis, R. Jeroen van Moorselaar, Connie R. Jimenez
Published 2017-12-01

Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells

by Dennis Poel, Lenka N.C. Boyd, Robin Beekhof, Tim Schelfhorst, Thang V. Pham, Sander R. Piersma, Jaco C. Knol, Connie R. Jimenez, Henk M.W. Verheul, Tineke E. Buffart
Published 2019-09-01

Peptide-mediated ‘miniprep’ isolation of extracellular vesicles is suitable for high-throughput proteomics

by Jaco C. Knol, Inge de Reus, Tim Schelfhorst, Robin Beekhof, Meike de Wit, Sander R. Piersma, Thang V. Pham, Egbert F. Smit, Henk M.W. Verheul, Connie R. Jiménez
Published 2016-06-01

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer

by Franziska Böttger, Ekaterina A. Semenova, Ji-Ying Song, Giustina Ferone, Jan van der Vliet, Miranda Cozijnsen, Rajith Bhaskaran, Lorenzo Bombardelli, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Anton Berns
Published 2019-06-01

Effects of Cancer Presence and Therapy on the Platelet Proteome

by Maudy Walraven, Siamack Sabrkhany, Jaco C. Knol, Henk Dekker, Inge de Reus, Sander R. Piersma, Thang V. Pham, Arjan W. Griffioen, Henk J. Broxterman, Mirjam Oude Egbrink, Henk M. W. Verheul, Connie R. Jimenez
Published 2021-07-01

Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy

by Maike Schuldt, Larissa M. Dorsch, Jaco C. Knol, Thang V. Pham, Tim Schelfhorst, Sander R. Piersma, Cris dos Remedios, Cris dos Remedios, Michelle Michels, Connie R. Jimenez, Diederik W. D. Kuster, Jolanda van der Velden
Published 2021-03-01

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

by Tessa Ya Sung Le Large, Btissame El Hassouni, Niccola Funel, Bart Kok, Sander R. Piersma, Thang V. Pham, Kenneth P. Olive, Geert Kazemier, Hanneke W.M. van Laarhoven, Connie R. Jimenez, Maarten F. Bijlsma, Elisa Giovannetti
Published 2019-05-01

Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding

by Rui-Jún Eveline Li, Aram de Haas, Ernesto Rodríguez, Hakan Kalay, Anouk Zaal, Connie R. Jimenez, Sander R. Piersma, Thang V. Pham, Alex A. Henneman, Richard R. de Goeij-de Haas, Sandra J. van Vliet, Yvette van Kooyk
Published 2021-04-01

Phosphoproteomic Characterization of Primary AML Samples and Relevance for Response Toward FLT3-inhibitors

by David G. J. Cucchi, Carolien Van Alphen, Sonja Zweegman, Bo Van Kuijk, Zinia J. Kwidama, Adil al Hinai, Alexander A. Henneman, Jaco C. Knol, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Jacqueline Cloos, Jeroen J. W. M. Janssen
Published 2021-07-01

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

by Robin Beekhof, Carolien vanAlphen, Alex A Henneman, Jaco C Knol, Thang V Pham, Frank Rolfs, Mariette Labots, Evan Henneberry, Tessa YS Le Large, Richard R deHaas, Sander R Piersma, Valentina Vurchio, Andrea Bertotti, Livio Trusolino, Henk MW Verheul, Connie R Jimenez
Published 2019-04-01

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

by Robin Beekhof, Carolien vanAlphen, Alex A Henneman, Jaco C Knol, Thang V Pham, Frank Rolfs, Mariette Labots, Evan Henneberry, Tessa YS Le Large, Richard R deHaas, Sander R Piersma, Valentina Vurchio, Andrea Bertotti, Livio Trusolino, Henk MW Verheul, Connie R Jimenez
Published 2019-05-01

Omics Analysis of Educated Platelets in Cancer and Benign Disease of the Pancreas

by Giulia Mantini, Laura L. Meijer, Ilias Glogovitis, Sjors G. J. G. In ‘t Veld, Rosita Paleckyte, Mjriam Capula, Tessa Y. S. Le Large, Luca Morelli, Thang V. Pham, Sander R. Piersma, Adam E. Frampton, Connie R. Jimenez, Geert Kazemier, Danijela Koppers-Lalic, Thomas Wurdinger, Elisa Giovannetti
Published 2021-12-01

Neutrophil degranulation interconnects over-represented biological processes in atrial fibrillation

by Makiri Kawasaki, Eva R. Meulendijks, Nicoline W. E. van den Berg, Fransisca A. Nariswari, Jolien Neefs, Robin Wesselink, Sarah W. E. Baalman, Aldo Jongejan, Tim Schelfhorst, Sander R. Piersma, Thang V. Pham, Wim J. P. van Boven, Antoine H. G. Driessen, Connie R. Jimenez, Joris R. de Groot
Published 2021-02-01

Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome

by Mariette Labots, Thang V. Pham, Richard J. Honeywell, Jaco C. Knol, Robin Beekhof, Richard de Goeij-de Haas, Henk Dekker, Maarten Neerincx, Sander R. Piersma, Johannes C. van der Mijn, Donald L. van der Peet, Martijn R. Meijerink, Godefridus J. Peters, Nicole C.T. van Grieken, Connie R. Jiménez, Henk M.W. Verheul
Published 2020-02-01

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

by Iris E Glykofridis, Jaco C Knol, Jesper A Balk, Denise Westland, Thang V Pham, Sander R Piersma, Sinéad M Lougheed, Sepide Derakhshan, Puck Veen, Martin A Rooimans, Saskia E van Mil, Franziska Böttger, Pino J Poddighe, Irma van de Beek, Jarno Drost, Fried JT Zwartkruis, Renee X de Menezes, Hanne EJ Meijers-Heijboer, Arjan C Houweling, Connie R Jimenez, Rob MF Wolthuis
Published 2021-01-01

Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

by Inger van Steenoven, Marleen J. A. Koel-Simmelink, Leonie J. M. Vergouw, Betty M. Tijms, Sander R. Piersma, Thang V. Pham, Claire Bridel, Gian-Luca Ferri, Cristina Cocco, Barbara Noli, Paul F. Worley, Mei-Fang Xiao, Desheng Xu, Patrick Oeckl, Markus Otto, Wiesje M. van der Flier, Frank Jan de Jong, Connie R. Jimenez, Afina W. Lemstra, Charlotte E. Teunissen
Published 2020-06-01

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

by Tiansheng Zhu, Yi Zhu, Yue Xuan, Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, Tim Schelfhorst, Richard R.G.D. Haas, Irene V. Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, Mo Hu, Yue Zhou, Winan J. Van Houdt, Tessa Y.S. Le Large, Jacqueline Cloos, Anna Wojtuszkiewicz, Danijela Koppers-Lalic, Franziska Böttger, Chantal Scheepbouwer, Ruud H. Brakenhoff, Geert J.L.H. van Leenders, Jan N.M. Ijzermans, John W.M. Martens, Renske D.M. Steenbergen, Nicole C. Grieken, Sathiyamoorthy Selvarajan, Sangeeta Mantoo, Sze S. Lee, Serene J.Y. Yeow, Syed M.F. Alkaff, Nan Xiang, Yaoting Sun, Xiao Yi, Shaozheng Dai, Wei Liu, Tian Lu, Zhicheng Wu, Xiao Liang, Man Wang, Yingkuan Shao, Xi Zheng, Kailun Xu, Qin Yang, Yifan Meng, Cong Lu, Jiang Zhu, Jin'e Zheng, Bo Wang, Sai Lou, Yibei Dai, Chao Xu, Chenhuan Yu, Huazhong Ying, Tony K. Lim, Jianmin Wu, Xiaofei Gao, Zhongzhi Luan, Xiaodong Teng, Peng Wu, Shi'ang Huang, Zhihua Tao, Narayanan G. Iyer, Shuigeng Zhou, Wenguang Shao, Henry Lam, Ding Ma, Jiafu Ji, Oi L. Kon, Shu Zheng, Ruedi Aebersold, Connie R. Jimenez, Tiannan Guo
Published 2020-04-01