Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts

by Thierry Besson, Corinne Fruit
Published 2021-07-01

Microwave-Assisted Sequential One-Pot Synthesis of 8-Substituted Pyrazolo[1,5-<i>a</i>][1,3,5]triazines

by Jonathan Elie, Corinne Fruit, Thierry Besson
Published 2021-06-01

Diaryliodoniums Salts as Coupling Partners for Transition-Metal Catalyzed <i>C</i>- and <i>N</i>-Arylation of Heteroarenes

by Alexandra Pacheco-Benichou, Thierry Besson, Corinne Fruit
Published 2020-04-01

26th Annual GP2A Medicinal Chemistry Conference &amp; 32nd Journées Franco-Belges de Pharmacochimie

by Patrick Dallemagne, Christophe Rochais, Pascal Marchand, Thierry Besson
Published 2019-05-01

Copper-Catalyzed C–H Arylation of Fused-Pyrimidinone Derivatives Using Diaryliodonium Salts

by Alexandra Pacheco-Benichou, Eugénie Ivendengani, Ioannis K. Kostakis, Thierry Besson, Corinne Fruit
Published 2021-12-01

Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases

by Damien Hédou, Julien Godeau, Nadège Loaëc, Laurent Meijer, Corinne Fruit, Thierry Besson
Published 2016-04-01

Microwave-Assisted Synthesis of Potential Bioactive Benzo-, Pyrido- or Pyrazino-thieno[3,2-<i>d</i>]pyrimidin-4-amine Analogs of MPC-6827

by Yvonnick Loidreau, Marie-Renée Nourrisson, Corinne Fruit, Cécile Corbière, Pascal Marchand, Thierry Besson
Published 2020-08-01

Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation

by Damien Hédou, Carole Dubouilh-Benard, Nadège Loaëc, Laurent Meijer, Corinne Fruit, Thierry Besson
Published 2016-06-01

Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald–Hartwig Coupling

by Joana F. Campos, Manon Cailler, Remi Claudel, Benjamin Prot, Thierry Besson, Sabine Berteina-Raboin
Published 2021-02-01

Exploring Kinase Inhibition Properties of 9<i>H</i>-pyrimido[5,4-<i>b</i>]- and [4,5-<i>b</i>]indol-4-amine Derivatives

by Yvonnick Loidreau, Carole Dubouilh-Benard, Marie-Renée Nourrisson, Nadège Loaëc, Laurent Meijer, Thierry Besson, Pascal Marchand
Published 2020-05-01

Synthesis of 2-Mercapto-(2-Oxoindolin-3-Ylidene)Acetonitriles from 3-(4-Chloro-5H-1,2,3-Dithiazol-5-Ylidene)Indolin-2-ones

by Boris Letribot, Régis Delatouche, Hervé Rouillard, Antoine Bonnet, Jean-René Chérouvrier, Lisianne Domon, Thierry Besson, Valérie Thiéry
Published 2018-06-01

Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II

by Alicia Foucourt, Damien Hédou, Carole Dubouilh-Benard, Angélique Girard, Thierry Taverne, Anne-Sophie Casagrande, Laurent Désiré, Bertrand Leblond, Thierry Besson
Published 2014-09-01

Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I

by Alicia Foucourt, Damien Hédou, Carole Dubouilh-Benard, Laurent Désiré, Anne-Sophie Casagrande, Bertrand Leblond, Nadège Loäec, Laurent Meijer, Thierry Besson
Published 2014-09-01

Development of Kinase Inhibitors via Metal-Catalyzed C–H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies

by Florence Couly, Marine Harari, Carole Dubouilh-Benard, Laetitia Bailly, Emilie Petit, Julien Diharce, Pascal Bonnet, Laurent Meijer, Corinne Fruit, Thierry Besson
Published 2018-08-01