Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay

by Vanessa Benham, Blair Bullard, Thomas S. Dexheimer, Matthew P. Bernard, Richard R. Neubig, Karen T. Liby, Jamie J. Bernard
Published 2019-07-01

A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein.

by Joseph Carver, Thomas S Dexheimer, Dennis Hsu, Meng-Tzu Weng, Jordan L Smith, Rajarshi Guha, Ajit Jadhav, Anton Simeonov, Ji Luo
Published 2014-01-01

Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in <i>NRAS</i>-Mutant Melanoma Cell Lines

by Kathryn M. Appleton, Charuta C. Palsuledesai, Sean A. Misek, Maja Blake, Joseph Zagorski, Kathleen A. Gallo, Thomas S. Dexheimer, Richard R. Neubig
Published 2021-04-01

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.

by Jonathan A Lee, Paul Shinn, Susan Jaken, Sarah Oliver, Francis S Willard, Steven Heidler, Robert B Peery, Jennifer Oler, Shaoyou Chu, Noel Southall, Thomas S Dexheimer, Jeffrey Smallwood, Ruili Huang, Rajarshi Guha, Ajit Jadhav, Karen Cox, Christopher P Austin, Anton Simeonov, G Sitta Sittampalam, Saba Husain, Natalie Franklin, David J Wild, Jeremy J Yang, Jeffrey J Sutherland, Craig J Thomas
Published 2015-01-01