The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse ModelsSummary

by Yoku Hayakawa, James G. Fox, Timothy C. Wang
Published 2017-05-01

Chronic inflammation, the tumor microenvironment and carcinogenesis

by Tamas A. Gonda, Shuiping Tu, Timothy C. Wang
Published 2009-09-01

Spectral characterization and unmixing of intrinsic contrast in intact normal and diseased gastric tissues using hyperspectral two-photon microscopy.

by Lauren E Grosberg, Andrew J Radosevich, Samuel Asfaha, Timothy C Wang, Elizabeth M C Hillman
Published 2011-01-01

Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus

by Yoku Hayakawa MD,, PhD, James G. Fox DVM,, PhD, Timothy C. Wang, MD
Published 2017-07-01

Mouse Models of Gastric Cancer

by Timothy C. Wang, Sureshkumar Muthupalani, Daniel L. Worthley, Tamas Gonda, James G. Fox, Yoku Hayakawa
Published 2013-01-01

Krüppel-like factor 4 regulates intestinal epithelial cell morphology and polarity.

by Tianxin Yu, Xi Chen, Wen Zhang, Juan Li, Ren Xu, Timothy C Wang, Walden Ai, Chunming Liu
Published 2012-01-01

Expression of Kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healing.

by Juan Li, Hai Zheng, Junfeng Wang, Fang Yu, Rebecca J Morris, Timothy C Wang, Shiang Huang, Walden Ai
Published 2012-01-01

Rapid gastrointestinal loss of Clostridial Clusters IV and XIVa in the ICU associates with an expansion of gut pathogens.

by Alexandra E Livanos, Erik J Snider, Susan Whittier, David H Chong, Timothy C Wang, Julian A Abrams, Daniel E Freedberg
Published 2018-01-01

Helicobacter pylori Infection Induces Anemia, Depletes Serum Iron Storage, and Alters Local Iron-Related and Adult Brain Gene Expression in Male INS-GAS Mice.

by Monika Burns, Sureshkumar Muthupalani, Zhongming Ge, Timothy C Wang, Vasudevan Bakthavatchalu, Catriona Cunningham, Kathleen Ennis, Michael Georgieff, James G Fox
Published 2015-01-01

Helicobacter pylori infection and low dietary iron alter behavior, induce iron deficiency anemia, and modulate hippocampal gene expression in female C57BL/6 mice.

by Monika Burns, Aldo Amaya, Caroline Bodi, Zhongming Ge, Vasudevan Bakthavatchalu, Kathleen Ennis, Timothy C Wang, Michael Georgieff, James G Fox
Published 2017-01-01

Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia

by Peiman Habibollahi, Todd Waldron, Pedram Heidari, Hoon Sung Cho, David Alcantara, Lee Josephson, Timothy C. Wang, Anil K. Rustgi, Umar Mahmood
Published 2014-05-01

Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK ActivationSummary

by Weiwei Sheng, Ermanno Malagola, Henrik Nienhüser, Zhengyu Zhang, Woosook Kim, Leah Zamechek, Antonia Sepulveda, Masahiro Hata, Yoku Hayakawa, Chun-Mei Zhao, Duan Chen, Timothy C. Wang
Published 2020-01-01

Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma.

by Cassandra L Miller, Sureshkumar Muthupalani, Zeli Shen, Frauke Drees, Zhongming Ge, Yan Feng, Xiaowei Chen, Guanyu Gong, Karan K Nagar, Timothy C Wang, Frank B Gertler, James G Fox
Published 2016-01-01

Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer

by Xiaowei Chen, Yoshihiro Takemoto, Huan Deng, Moritz Middelhoff, Richard A. Friedman, Timothy H. Chu, Michael J. Churchill, Yan Ma, Karan K. Nagar, Yagnesh H. Tailor, Siddhartha Mukherjee, Timothy C. Wang
Published 2017-03-01

Notch signaling drives development of Barrett’s metaplasia from Dclk1-positive epithelial tuft cells in the murine gastric mucosa

by Bettina Kunze, Moritz Middelhoff, H. Carlo Maurer, Tatiana Agibalova, Akanksha Anand, Anne-Marie Bührer, Hsin-Yu Fang, Theresa Baumeister, Katja Steiger, Julia Strangmann, Roland M. Schmid, Timothy C. Wang, Michael Quante
Published 2021-02-01

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer

by Dongfeng Qu, Nathaniel Weygant, Jiannan Yao, Parthasarathy Chandrakesan, William L. Berry, Randal May, Kamille Pitts, Sanam Husain, Stan Lightfoot, Min Li, Timothy C. Wang, Guangyu An, Cynthia Clendenin, Ben Z. Stanger, Courtney W. Houchen
Published 2019-01-01

Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms

by Heuijoon Park, Sonali Lad, Kelsey Boland, Kelly Johnson, Nyssa Readio, Guangchun Jin, Samuel Asfaha, Kelly S. Patterson, Ashok Singh, Xiangdong Yang, Douglas Londono, Anupama Singh, Carol Trempus, Derek Gordon, Timothy C. Wang, Rebecca J. Morris
Published 2018-12-01

Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCsSummary

by Na Fu, Feijing Wu, Zhengyu Jiang, Woosook Kim, Tuo Ruan, Ermanno Malagola, Yosuke Ochiai, Osmel Companioni Nápoles, Giovanni Valenti, Ruth A. White, Bryana R. Belin, Leah B. Zamechek, Jonathan S. LaBella, Timothy C. Wang
Published 2021-01-01

Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells.

by J Dinesh Kumar, Chris Holmberg, Sandhir Kandola, Islay Steele, Peter Hegyi, Laszlo Tiszlavicz, Rosalind Jenkins, Robert J Beynon, David Peeney, Olivier T Giger, Ahlam Alqahtani, Timothy C Wang, Trevor T Charvat, Mark Penfold, Graham J Dockray, Andrea Varro
Published 2014-01-01

Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

by Moritz Middelhoff, Henrik Nienhüser, Giovanni Valenti, H. Carlo Maurer, Yoku Hayakawa, Ryota Takahashi, Woosook Kim, Zhengyu Jiang, Ermanno Malagola, Krystle Cuti, Yagnesh Tailor, Leah B. Zamechek, Bernhard W. Renz, Michael Quante, Kelley S. Yan, Timothy C. Wang
Published 2020-01-01