Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen.

by Jie Liu, Zehua Zuo, Meijuan Zou, Toren Finkel, Shihui Liu
Published 2020-10-01

Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line

by Daniel I. Sullivan, Daniel I. Sullivan, Mao Jiang, Mao Jiang, Angela M. Hinchie, Mark G. Roth, Harinath Bahudhanapati, Harinath Bahudhanapati, Mehdi Nouraie, Mehdi Nouraie, Jie Liu, Jie Liu, Jie Liu, John F. McDyer, Rama K. Mallampalli, Yingze Zhang, Yingze Zhang, Daniel J. Kass, Daniel J. Kass, Toren Finkel, Toren Finkel, Toren Finkel, Jonathan K. Alder, Jonathan K. Alder
Published 2021-02-01

A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs

by Yihan Zhao, Di Wu, Danli Jiang, Xiaoyu Zhang, Ting Wu, Jing Cui, Min Qian, Jean Zhao, Steffi Oesterreich, Wei Sun, Toren Finkel, Gang Li
Published 2020-07-01

Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner

by Maria Paola Santini, Daniela Malide, Gabriel Hoffman, Gaurav Pandey, Valentina D’Escamard, Aya Nomura-Kitabayashi, Ilsa Rovira, Hiroshi Kataoka, Jordi Ochando, Richard P. Harvey, Toren Finkel, Jason C. Kovacic
Published 2020-01-01

MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload

by Julia C. Liu, Jie Liu, Kira M. Holmström, Sara Menazza, Randi J. Parks, Maria M. Fergusson, Zu-Xi Yu, Danielle A. Springer, Charles Halsey, Chengyu Liu, Elizabeth Murphy, Toren Finkel
Published 2016-08-01

TGF-β receptor 1 regulates progenitors that promote browning of white fat

by Umesh D. Wankhade, Ji-Hyeon Lee, Pradeep K. Dagur, Hariom Yadav, Michael Shen, Weiping Chen, Ashok B. Kulkarni, J. Philip McCoy, Toren Finkel, Aaron M. Cypess, Sushil G. Rane
Published 2018-10-01

Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

by Sai P. Pydi, Shanu Jain, Wesley Tung, Yinghong Cui, Lu Zhu, Wataru Sakamoto, Shalini Jain, Brent S. Abel, Monica C. Skarulis, Jie Liu, Thanh Huynh, Karel Pacak, Marc G. Caron, Oksana Gavrilova, Toren Finkel, Jürgen Wess
Published 2019-07-01

Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.

by Ryan Houston, Shiori Sekine, Michael J Calderon, Fayaz Seifuddin, Guanghui Wang, Hiroyuki Kawagishi, Daniela A Malide, Yuesheng Li, Marjan Gucek, Mehdi Pirooznia, Alissa J Nelson, Matthew P Stokes, Jacob Stewart-Ornstein, Steven J Mullett, Stacy G Wendell, Simon C Watkins, Toren Finkel, Yusuke Sekine
Published 2020-11-01

Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression

by J. Julie Wu, Jie Liu, Edmund B. Chen, Jennifer J. Wang, Liu Cao, Nisha Narayan, Marie M. Fergusson, Ilsa I. Rovira, Michele Allen, Danielle A. Springer, Cory U. Lago, Shuling Zhang, Wendy DuBois, Theresa Ward, Rafael deCabo, Oksana Gavrilova, Beverly Mock, Toren Finkel
Published 2013-09-01

A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry

by Yanwen Chen, Travis B. Lear, John W. Evankovich, Mads B. Larsen, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Laura Salminen, Daniel P. Camarco, Karina C. Lockwood, Ferhan Tuncer, Jie Liu, Michael M. Myerburg, John F. McDyer, Yuan Liu, Toren Finkel, Bill B. Chen
Published 2021-06-01

Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit

by Yoram Vodovotz, Neal Barnard, Frank B. Hu, John Jakicic, Liana Lianov, David Loveland, Daniel Buysse, Eva Szigethy, Toren Finkel, Gwendolyn Sowa, Paul Verschure, Kim Williams, Eduardo Sanchez, Wayne Dysinger, Victoria Maizes, Caesar Junker, Edward Phillips, David Katz, Stacey Drant, Richard J. Jackson, Leonardo Trasande, Steven Woolf, Marcel Salive, Jeannette South-Paul, Sarah L. States, Loren Roth, Gary Fraser, Ron Stout, Michael D. Parkinson
Published 2020-12-01