Sugar-Recognizing Ubiquitin Ligases: Action Mechanisms and Physiology

by Yukiko Yoshida, Tsunehiro Mizushima, Keiji Tanaka
Published 2019-02-01

Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition

by Minsoo Kim, Ryota Otsubo, Hanako Morikawa, Akira Nishide, Kenji Takagi, Chihiro Sasakawa, Tsunehiro Mizushima
Published 2014-08-01

An archaeal homolog of proteasome assembly factor functions as a proteasome activator.

by Kentaro Kumoi, Tadashi Satoh, Kazuyoshi Murata, Takeshi Hiromoto, Tsunehiro Mizushima, Yukiko Kamiya, Masanori Noda, Susumu Uchiyama, Hirokazu Yagi, Koichi Kato
Published 2013-01-01

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.

by Taichi Kumanomidou, Kazuya Nishio, Kenji Takagi, Tomomi Nakagawa, Atsuo Suzuki, Takashi Yamane, Fuminori Tokunaga, Kazuhiro Iwai, Arisa Murakami, Yukiko Yoshida, Keiji Tanaka, Tsunehiro Mizushima
Published 2015-01-01

Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism

by Yuta Horie, Takafumi Suzuki, Jin Inoue, Tatsuro Iso, Geoffrey Wells, Terry W. Moore, Tsunehiro Mizushima, Albena T. Dinkova-Kostova, Takuma Kasai, Takashi Kamei, Seizo Koshiba, Masayuki Yamamoto
Published 2021-05-01

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization

by Hiroaki Fujita, Akira Tokunaga, Satoshi Shimizu, Amanda L. Whiting, Francisco Aguilar-Alonso, Kenji Takagi, Erik Walinda, Yoshiteru Sasaki, Taketo Shimokawa, Tsunehiro Mizushima, Izuru Ohki, Mariko Ariyoshi, Hidehito Tochio, Federico Bernal, Masahiro Shirakawa, Kazuhiro Iwai
Published 2018-04-01

p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

by Shun Kageyama, Sigurdur Runar Gudmundsson, Yu-Shin Sou, Yoshinobu Ichimura, Naoki Tamura, Saiko Kazuno, Takashi Ueno, Yoshiki Miura, Daisuke Noshiro, Manabu Abe, Tsunehiro Mizushima, Nobuaki Miura, Shujiro Okuda, Hozumi Motohashi, Jin-A Lee, Kenji Sakimura, Tomoyuki Ohe, Nobuo N. Noda, Satoshi Waguri, Eeva-Liisa Eskelinen, Masaaki Komatsu
Published 2021-01-01

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

by Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi, Takafumi Suzuki, Tsunehiro Mizushima, Kenji Takagi, Yuki Hirose, Masayuki Nagahashi, Tetsuro Iso, Toshiaki Fukutomi, Maki Ohishi, Keiko Endo, Takefumi Uemura, Yasumasa Nishito, Shujiro Okuda, Miki Obata, Tsuguka Kouno, Riyo Imamura, Yukio Tada, Rika Obata, Daisuke Yasuda, Kyoko Takahashi, Tsutomu Fujimura, Jingbo Pi, Myung-Shik Lee, Takashi Ueno, Tomoyuki Ohe, Tadahiko Mashino, Toshifumi Wakai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Hozumi Motohashi, Satoshi Waguri, Tomoyoshi Soga, Masayuki Yamamoto, Keiji Tanaka, Masaaki Komatsu
Published 2016-06-01