X‐linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery

by Jianbiao Zhou, Xiao Lu, Tuan Zea Tan, Wee‐Joo Chng
Published 2018-01-01

BET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemia

by Yafeng Zhou, Jianbiao Zhou, Xiao Lu, Tuan-Zea Tan, Wee-Joo Chng
Published 2018-07-01

DNA Methylation Profiling of Breast Cancer Cell Lines along the Epithelial Mesenchymal Spectrum—Implications for the Choice of Circulating Tumour DNA Methylation Markers

by Anh Viet-Phuong Le, Marcin Szaumkessel, Tuan Zea Tan, Jean-Paul Thiery, Erik W. Thompson, Alexander Dobrovic
Published 2018-08-01

Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse

by Rabeah A. Al-Temaimi, Tuan Zea Tan, Makia J. Marafie, Jean Paul Thiery, Philip Quirke, Fahd Al-Mulla
Published 2016-04-01

Correction: Sundararajan, V., et al. SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2. <i>Cancers</i> 2020, <i>12</i>, 1140

by Vignesh Sundararajan, Ming Tan, Tuan Zea Tan, Qing You Pang, Jieru Ye, Vin Yee Chung, Ruby Yun-Ju Huang
Published 2020-12-01

SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2

by Vignesh Sundararajan, Ming Tan, Tuan Zea Tan, Qing You Pang, Jieru Ye, Vin Yee Chung, Ruby Yun-Ju Huang
Published 2020-05-01

Analysis of gene expression signatures identifies prognostic and functionally distinct ovarian clear cell carcinoma subtypes

by Tuan Zea Tan, Jieru Ye, Chung Vin Yee, Diana Lim, Natalie Yan Li Ngoi, David Shao Peng Tan, Ruby Yun-Ju Huang
Published 2019-12-01

Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity

by Stéphane Terry, Stéphanie Buart, Tuan Zea Tan, Gwendoline Gros, Muhammad Zaeem Noman, James B. Lorens, Fathia Mami-Chouaib, Jean Paul Thiery, Salem Chouaib
Published 2017-02-01

Molecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clusters.

by Meng Ling Choong, Shan Ho Tan, Tuan Zea Tan, Sravanthy Manesh, Anna Ngo, Jacklyn W Y Yong, Henry He Yang, May Ann Lee
Published 2014-01-01

RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair

by Lavina Sierra Tay, Vaidehi Krishnan, Haresh Sankar, Yu Lin Chong, Linda Shyue Huey Chuang, Tuan Zea Tan, Arun Mouli Kolinjivadi, Dennis Kappei, Yoshiaki Ito
Published 2018-08-01

The FZD7‐TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma

by Ming Tan, Mohammad Asad, Valerie Heong, Meng Kang Wong, Tuan Zea Tan, Jieru Ye, Kuee Theng Kuay, Jean Paul Thiery, Clare Scott, Ruby Yun‐Ju Huang
Published 2019-04-01

EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway.

by Dominic Chih-Cheng Voon, Huajing Wang, Jason Kin Wai Koo, Juin Hsien Chai, Yit Teng Hor, Tuan Zea Tan, Yeh-Shiu Chu, Seiichi Mori, Yoshiaki Ito
Published 2013-01-01

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

by Jianbiao Zhou, Sabrina Hui-Min Toh, Zit-Liang Chan, Jessie Yiying Quah, Jing-Yuan Chooi, Tuan Zea Tan, Phyllis S. Y. Chong, Qi Zeng, Wee-Joo Chng
Published 2018-03-01

Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective

by Mei Shan Ong, Shuo Deng, Clarissa Esmeralda Halim, Wanpei Cai, Tuan Zea Tan, Ruby Yun-Ju Huang, Gautam Sethi, Shing Chuan Hooi, Alan Prem Kumar, Celestial T. Yap
Published 2020-01-01

Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

by Malina Xiao, Meriem Hasmim, Audrey Lequeux, Kris Van Moer, Tuan Zea Tan, Christine Gilles, Brett G. Hollier, Jean Paul Thiery, Guy Berchem, Bassam Janji, Muhammad Zaeem Noman
Published 2021-03-01

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

by Jianbiao Zhou, Chonglei Bi, Ying Qing Ching, Jing-Yuan Chooi, Xiao Lu, Jessie Yiying Quah, Sabrina Hui-Min Toh, Zit-Liang Chan, Tuan Zea Tan, Phyllis SY Chong, Wee-Joo Chng
Published 2017-07-01

Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis

by Arpita Datta, Shuo Deng, Vennila Gopal, Kenneth Chun-Hong Yap, Clarissa Esmeralda Halim, Mun Leng Lye, Mei Shan Ong, Tuan Zea Tan, Gautam Sethi, Shing Chuan Hooi, Alan Prem Kumar, Celestial T. Yap
Published 2021-04-01

Blocking Aerobic Glycolysis by Targeting Pyruvate Dehydrogenase Kinase in Combination with EGFR TKI and Ionizing Radiation Increases Therapeutic Effect in Non-Small Cell Lung Cance...

by Sissel E. Dyrstad, Maria L. Lotsberg, Tuan Zea Tan, Ina K. N. Pettersen, Silje Hjellbrekke, Deusdedit Tusubira, Agnete S. T. Engelsen, Thomas Daubon, Arnaud Mourier, Jean Paul Thiery, Olav Dahl, James B. Lorens, Karl Johan Tronstad, Gro V. Røsland
Published 2021-02-01

Erratum: Iyer, A., et al. Integrative Analysis and Machine Learning Based Characterization of Single Circulating Tumor Cells. <i>J. Clin. Med.</i> 2020, <i>9</i>, 1206

by Arvind Iyer, Krishan Gupta, Shreya Sharma, Kishore Hari, Yi Fang Lee, Neevan Ramalingam, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Balaram Vishnu Subramani, Burhanuddin Sabuwala, Tuan Zea Tan, Jean Paul Thiery, Mohit Kumar Jolly, Naveen Ramalingam, Debarka Sengupta
Published 2021-01-01

Integrative Analysis and Machine Learning based Characterization of Single Circulating Tumor Cells

by Arvind Iyer, Krishan Gupta, Shreya Sharma, Kishore Hari, Yi Fang Lee, Neevan Ramalingam, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Balaram Vishnu Subramani, Burhanuddin Sabuwala, Tuan Zea Tan, Jean Paul Thiery, Mohit Kumar Jolly, Naveen Ramalingam, Debarka Sengupta
Published 2020-04-01