2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels

by Rafel Simó-Vicens, Rafel Simó-Vicens, Sofia H. Bomholtz, Sofia H. Bomholtz, Ulrik S. Sørensen, Bo H. Bentzen, Bo H. Bentzen
Published 2018-12-01

The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

by Jonas Goldin Diness, Jeppe Egedal Kirchhoff, Tobias Speerschneider, Tobias Speerschneider, Lea Abildgaard, Nils Edvardsson, Nils Edvardsson, Ulrik S. Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Bo Hjorth Bentzen
Published 2020-02-01

Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

by Jonas Goldin Diness, Lea Abildgaard, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Mark Alexander Skarsfeldt, Mark Alexander Skarsfeldt, Nils Edvardsson, Nils Edvardsson, Ulrik S. Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Bo Hjorth Bentzen
Published 2020-05-01

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

by Jeppe Egedal Kirchhoff, Mark Alexander Skarsfeldt, Kalai Mangai Muthukumarasamy, Rafel Simó-Vicens, Rafel Simó-Vicens, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Lea Abildgaard, Thomas Jespersen, Ulrik S. Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Bo Hjorth Bentzen, Jonas Goldin Diness
Published 2019-06-01

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

by Bo Hjorth Bentzen, Bo Hjorth Bentzen, Sofia Hammami Bomholtz, Sofia Hammami Bomholtz, Rafel Simó-Vicens, Rafel Simó-Vicens, Lasse Folkersen, Lea Abildgaard, Tobias Speerschneider, Tobias Speerschneider, Kalai Mangai Muthukumarasamy, Nils Edvardsson, Nils Edvardsson, Ulrik S. Sørensen, Morten Grunnet, Jonas Goldin Diness
Published 2020-05-01