Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain

by Edoardo Parrella, Valter D. Longo
Published 2010-01-01

Intermittent and Periodic Fasting, Hormones, and Cancer Prevention

by Giulia Salvadori, Mario Giuseppe Mirisola, Valter D. Longo
Published 2021-09-01

Significant and systematic expression differentiation in long-lived yeast strains.

by Chao Cheng, Paola Fabrizio, Huanying Ge, Min Wei, Valter D Longo, Lei M Li
Published 2007-10-01

Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.

by Mario G Mirisola, Giusi Taormina, Paola Fabrizio, Min Wei, Jia Hu, Valter D Longo
Published 2014-02-01

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9.

by Min Wei, Paola Fabrizio, Jia Hu, Huanying Ge, Chao Cheng, Lei Li, Valter D Longo
Published 2008-01-01

Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.

by Min Wei, Paola Fabrizio, Federica Madia, Jia Hu, Huanying Ge, Lei M Li, Valter D Longo
Published 2009-05-01

Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.

by Paola Fabrizio, Shawn Hoon, Mehrnaz Shamalnasab, Abdulaye Galbani, Min Wei, Guri Giaever, Corey Nislow, Valter D Longo
Published 2010-07-01

Fasting enhances the response of glioma to chemo- and radiotherapy.

by Fernando Safdie, Sebastian Brandhorst, Min Wei, Weijun Wang, Changhan Lee, Saewon Hwang, Peter S Conti, Thomas C Chen, Valter D Longo
Published 2012-01-01

Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers

by Maira Di Tano, Franca Raucci, Claudio Vernieri, Irene Caffa, Roberta Buono, Maura Fanti, Sebastian Brandhorst, Giuseppe Curigliano, Alessio Nencioni, Filippo de Braud, Valter D. Longo
Published 2020-05-01

Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

by Priya Rangan, Inyoung Choi, Min Wei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral Maesincee, Vanessa Ocon, Maya Abdulridha, Valter D. Longo
Published 2019-03-01

Correction: Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy.

by Stefano Di Biase, Hong Seok Shim, Kyung Hwa Kim, Manlio Vinciguerra, Francesca Rappa, Min Wei, Sebastian Brandhorst, Francesco Cappello, Hamed Mirzaei, Changhan Lee, Valter D Longo
Published 2017-05-01

Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy.

by Stefano Di Biase, Hong Seok Shim, Kyung Hwa Kim, Manlio Vinciguerra, Francesca Rappa, Min Wei, Sebastian Brandhorst, Francesco Cappello, Hamed Mirzaei, Changhan Lee, Valter D Longo
Published 2017-03-01

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

by In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Michalsen, Anne H. Cross, Todd E. Morgan, Min Wei, Friedemann Paul, Markus Bock, Valter D. Longo
Published 2016-06-01

Correction to: Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a f...

by Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans, Hanno Pijl
Published 2020-11-01

Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimickin...

by Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans, Hanno Pijl
Published 2020-06-01

Safety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment

by Francesca Valdemarin, Irene Caffa, Angelica Persia, Anna Laura Cremonini, Lorenzo Ferrando, Luca Tagliafico, Alberto Tagliafico, Ana Guijarro, Federico Carbone, Stefano Ministrini, Maria Bertolotto, Pamela Becherini, Tommaso Bonfiglio, Chiara Giannotti, Amr Khalifa, Moustafa Ghanem, Michele Cea, Marzia Sucameli, Roberto Murialdo, Valentina Barbero, Raffaella Gradaschi, Francesca Bruzzone, Consuelo Borgarelli, Matteo Lambertini, Claudio Vernieri, Gabriele Zoppoli, Valter D. Longo, Fabrizio Montecucco, Samir G. Sukkar, Alessio Nencioni
Published 2021-08-01

Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial

by Stefanie de Groot, Rieneke T. Lugtenberg, Danielle Cohen, Marij J. P. Welters, Ilina Ehsan, Maaike P. G. Vreeswijk, Vincent T. H. B. M. Smit, Hiltje de Graaf, Joan B. Heijns, Johanneke E. A. Portielje, Agnes J. van de Wouw, Alex L. T. Imholz, Lonneke W. Kessels, Suzan Vrijaldenhoven, Arnold Baars, Elma Meershoek-Klein Kranenbarg, Marjolijn Duijm-de Carpentier, Hein Putter, Jacobus J. M. van der Hoeven, Johan W. R. Nortier, Valter D. Longo, Hanno Pijl, Judith R. Kroep, Dutch Breast Cancer Research Group (BOOG)
Published 2020-06-01